Abbreviation: J. Diabetes Endocrinol.
Start Year: 2010
Page 1 of 3, showing 20 records out of 52 total, starting on record 1, ending on 20
DOI: 10.5897/JDE2017.0111[Article Number: 05FA62065644]
This study was designed to demonstrate the relationship between 25-hydroxy vitamin D (25(OH)D) levels and insulin resistance (IR) in normal pregnancy and in gestational diabetes mellitus (GDM). The study included 103 pregnant women classified into two main groups: normal pregnant (n= 48) and GDM (n= 55). Further classification for each group was carried out based on 25(OH)D status (deficient, insufficient and... Read more.
DOI: 10.5897/JDE2017.0110[Article Number: 40AEE5D65219]
It is well established that diabetic patients with poor glycemic control have increased susceptibility to infections, but glucose levels have not been directly associated with this increase. The assessment of the effects of glycosylated hemoglobin (A1 c) on the body’s ability to fight infections may be useful directly in establishing a link between elevated blood sugar and the risk of infections. A total of 127... Read more.
DOI: 10.5897/JDE2016.0102[Article Number: 5F1633562394]
This study aimed to assess HbA1c performance against single fasting blood glucose (FBG) for diagnosis of undiagnosed type 2 diabetes (T2D) and impaired fasting glycaemia (IFG) among general medical outpatients in Botswana. Participants aged, ≥20 years were cross-sectionally surveyed from August to October, 2014. All the participants underwent testing for HbA1c and FBG. The HbA1c sensitivity, specificity and... Read more.
DOI: 10.5897/JDE2016.0098[Article Number: 0CB304761030]
A 21-year-old male presented to us with delayed development of secondary sexual characteristics. Based on examination and investigations, a diagnosis of idiopathic hypogonadotropic hypogonadism was made and the patient was started on testosterone therapy. After around a year of therapy the patient had an increase in bilateral testicular volume with increased serum luteinizing hormone (LH) values. The patient was advised... Read more.
DOI: 10.5897/JDE2015.0091[Article Number: 718032158653]
Ectopic growth hormone releasing hormone (GHRH) secretion is a rare cause of acromegaly and accounts for <1% of cases. It is most commonly secondary to gastropancreatic neuroendocrine tumours and bronchial carcinoid tumours. We report a case of 57 years old man with adrenal phaeochromocytoma and acromegaly due to ectopic GHRH secretion in a patient with neurofibromatosis type 1. He presented with headache, sweating... Read more.
DOI: 10.5897/JDE2015.0086[Article Number: 2E37CE452746]
Diabetes mellitus (DM) is a common endocrine metabolic disorder and a leading cause of death worldwide. Dyslipidemia is a well-recognized manifestation of uncontrolled DM, because insulin has important regulatory effects on lipid metabolism. This study was conducted to determine the frequency and pattern of dyslipidaemia in diabetic patients. Cross-sectional study was conducted on a total of two hundred ninety five... Read more.
DOI: 10.5897/JDE2015.0084[Article Number: B7DC4A351481]
Obesity has reached epidemic proportions globally, and is now prevalent in low-income and middle-income countries. This study sets out to determine the prevalence of obesity as well as its predictors in rural South-Western Nigeria. Cross-sectional descriptive survey of 416 participants aged 20 to 70 years in two rural communities in Remo North Local Government area of Ogun State, Nigeria was taken. Relevant clinical and... Read more.
DOI: 10.5897/JDE2014.0083[Article Number: FC4930850423]
Children’s diabetes is represented by the Type 1 diabetes mellitus (T1DM). In T1DM, the persistence of hyperglycemia has been reported to cause increased production of oxygen free radicals through glucose autooxidation and nonenzymatic glycation. The aim of this study was to evaluate markers of oxidant/antioxidant status in diabetic children of Western Algeria. This study included 40 children with T1DM with mean... Read more.
DOI: 10.5897/JDE2014.0082[Article Number: DD2CD9D49975]
The objective of this study was to describe a constellation of rare pediatric disorders, pulmonary arterial hypertension (PAH) and autoimmune polyendocrine syndromes (APS). This study present a brief report of a child diagnosed with autoimmune type 1 diabetes mellitus (T1DM) at age 11 and with PAH three years later, when he was re-presented with symptoms of chest pain, lethargy, syncope and vomiting. Following a saline... Read more.
DOI: 10.5897/JDE2014.0077[Article Number: A710EFF45002]
Increasing evidence suggests that oxidative stress and inflammation play major roles in diabetes mellitus and its complications. Furthermore, hyperglycemia increases the production of free radicals, resulting in oxidative stress. Minocycline presents potent anti-inflammatory and antioxidant activities, as evaluated by in vivo and in vitro models. In the present study, the minocycline anti-diabetic effect was assessed in... Read more.
DOI: 10.5897/JDE2014.0076[Article Number: 437206944093]
Herbal products are an affective move towards the treatment of diabetes and impeding its complications. However, there have been no reports to date on Commiphora wightii (EACWR) for the treatment of diabetes and its associated metabolism. Oral administration of EACWR (400 mg/kg body weight) to streptozotocin (STZ) induced diabetic rats effectively elevated body weight, plasma insulin level, hepatic and skeletal muscle... Read more.
DOI: 10.5897/JDE2013.0068[Article Number: A5CF86C46816]
Chronic kidney disease is a worldwide public health problem and a chronic disease that deteriorates the quality of life (QOL). Diabetes is recognized as co-morbidity in patients of end stage renal disease (ESRD). This study evaluated QOL in diabetic and non-diabetic patients on maintenance dialysis therapy. A cross-sectional study was conducted on ESRD with or without diabetes on hemodialysis therapy for at least three... Read more.
DOI: 10.5897/JDE2013.0071[Article Number: F177E3242280]
We read with great interest the Mahmoodi et al.'s (2013) article published in the January issue of the Journal of Diabetes and Endocrinology. The authors investigated some hematological and blood biochemical factors in type 2 diabetic patients in a double blind randomized controlled trial (RCT). One of the queries about this study is the random allocation. According to the standard criteria for RCT study design... Read more.
DOI: 10.5897/JDE2013.0072[Article Number: 316D89D42281]
A 30-year-old woman diagnosed with type 1 diabetes mellitus attended 2-year Conjunctive Group Therapy in parallel with medical treatment at a Greek state hospital. The study focuses on the patient’s changes in terms of attitudes and metabolic control after termination of the intervention. Qualitative data was collected from focused interviews before and after the intervention and thematic analysis was performed;... Read more.
DOI: 10.5897/JDE2013.0069[Article Number: 1D4F8B14444]
This study was carried out to investigate the hepato-protective properties of combined extracts of Moringa oleifera (MO) and Vernonia amygdalina (VA) in streptozotocin (STZ) induced diabetic albino Wistar rats. The study design involved 42 rats weighing 120 to 180 g which were divided into 7 groups of 6 rats each. Groups 1 and 2 representing normal and diabetic control (NC and DC) received 0.5 ml of... Read more.
DOI: 10.5897/JDE2013.0070[Article Number: B1452FE4454]
After the introduction of dipeptidylpeptidase-4 (DPP-4) inhibitors into the treatment for diabetes, these drugs have been widely used because of their capability and safety. Therefore, the clinical efficacy of linagliptin to sitagliptin was compared. Patients with type 2 diabetes, in whom pharmacological treatment was recently started, were randomly assigned to two separate groups, namely sitagliptin (50 mg/day) group... Read more.
DOI: 10.5897/JDE09.014[Article Number: FD118FF4423]
Type 2 diabetes mellitus (DM) has recently been described as “coronary risk equivalent”. Lipoprotein metabolism disorder in type 2 DM is known as diabetic dyslipidemia. Dyslipidemia contributes to a substantial percentage in cardiovascular mortality and morbidity in diabetic patients. National Cholesterol Education Program (NCEP) and American Diabetic Association (ADA) have provided recent guidelines for... Read more.
DOI: 10.5897/JDE2013.0065[Article Number: 6277E7E4433]
The purpose of this study was to assess the effectiveness of continued education and multiprofessional care for type 1 diabetes mellitus patients as a strategy for long-term glycemic control evaluated by glycosylated hemoglobin (A1C) levels. This study is a retrospective, observational study of the Diabetes Objective Control and Education (DOCE) Project. A group of 74 patients accompanied by family member attended... Read more.
DOI: 10.5897/JDE12.015[Article Number: 6C2FDA34403]
Carotid intimo medial thickness (cIMT) is a sensitive screening tool for cardiac evaluation, but there are limited studies evaluating its role in type 1 diabetes mellitus (T1DM) in developing countries. Thirty diagnosed adolescent type 1 diabetics on conventional insulin regime were included. Their glycated hemoglobin (HbA1C) and lipid profile were measured. Their cardiovascular function (determined by cIMT) was... Read more.
DOI: 10.5897/JDE12.018[Article Number: 305EB9C4411]
Diabetes is a metabolic disorder characterized by hyperglycemia (excessive amount of glucose) and is associated with abnormal lipid and protein metabolism.This was the first study done in Vindhyan region. The population size selected in this study was 400 (190 cases of diabetes and 210 healthy control). Anthropometric data was collected during sample collection. Genetic polymorphism study of ectonucleotide... Read more.
Page 1 of 3, showing 20 records out of 52 total, starting on record 1, ending on 20