African Journal of Biochemistry Research
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Article Number - 1C4D19C11705

Vol.7(9), pp. 179-183 , October 2013

ISSN: 1996-0778

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Full Length Research Paper

The effects of Yucca schidigera on blood glucose and lipid levels in diabetic rats




Department of Physiology, Faculty of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey.

Email: [email protected]

 Accepted: 19 March 2013  Published: 31 October 2013

Copyright © 2013 Author(s) retain the copyright of this article.
This article is published under the terms of the Creative Commons Attribution License 4.0


The aim of this study was to investigate the effects of Yucca schidigera (YSE) on lipid peroxidation and some biochemical parameters in streptozotocin-induced (STZ) diabetic rats. Four groups of seven rats each were used in this study. Supplementation period was three weeks. The groups were: I. control group (C), normal feed; II. diabetic (DM-YSE), normal feed plus YSE 100 ppm/kg; III. diabetic (DM), normal feed; and IV. yucca group (YSE), normal feed plus YSE 100 ppm/kg. malondialdehyde, glutathione, cholesterol, triglyceride and glucose levels were measured by spectrophotometric methods whereas insulin and leptin levels were measured by ELISA. Pancreatic tissues were examined to distinguish histopathological changes. YSE had increased plasma insulin levels in yucca group compared to the diabetics. There was no significant difference in leptin levels between control and diabetic groups while a significant increase was observed in YSE fed groups compared to others. There was no significant difference among four groups in terms of triglyceride or cholesterol levels. No histological anomalies were observed in pancreatic tissues when compared to the control group, however, STZ-DM induced changes were detected. According to the results of the study, YSE does not have a direct effect on glucose levels in diabetics, however it may act through insulin.


Key words: Diabetes Mellitus, Oxidative stress, Yucca schidigera, Histopathological changes.

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APA (2013). The effects of Yucca schidigera on blood glucose and lipid levels in diabetic rats. African Journal of Biochemistry Research , 7(9), 179-183.
Chicago   Nuray OZTASAN. "The effects of Yucca schidigera on blood glucose and lipid levels in diabetic rats." African Journal of Biochemistry Research 7, no. 9 (2013): 179-183.
MLA   Nuray OZTASAN. "The effects of Yucca schidigera on blood glucose and lipid levels in diabetic rats." African Journal of Biochemistry Research 7.9 (2013): 179-183.

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