African Journal of
Biochemistry Research

  • Abbreviation: Afr. J. Biochem. Res.
  • Language: English
  • ISSN: 1996-0778
  • DOI: 10.5897/AJBR
  • Start Year: 2007
  • Published Articles: 424

Table of Content: November 2017; 11(11)

November 2017

Therapeutic effect of an alkaloid-rich fraction of Abrus precatorius seed methanol extract on paracetamol-induced liver damage in rats

The therapeutic effect of an alkaloid-rich fraction of the chloroform-methanol extract of Abrus precatorius seeds on paracetamol-induced hepatotoxicity in rats was investigated in this study. The extract was fractionated in a 17.5 × 2.5 cm Sephadex G15 swollen, packed and eluted with water. The fractions were spotted on F2.54 pre-coated thin layer chromatography (TLC) plates and sprayed with Drangendorff’s...

Author(s): Ukegbu Chimere Young, Parker Elijah Joshua, Okwesili Fred Nwodo C., and Iroha Okechukwu