African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2084

Full Length Research Paper

Phytochemical analysis and ovicidal activity of Cassia sieberiana, Guiera senegalensis and Excoecaria grahamii extracts

Aristide TRAORE
  • Aristide TRAORE
  • Département Médecine et Pharmacopée Traditionnelles/ Pharmacie (MEPHATRA-PH), Institut de Recherche en Sciences de la Santé (IRSS/CNRST), 03 BP 7192 Ouagadougou 03, Burkina Faso.
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Sylvin OUEDRAOGO
  • Sylvin OUEDRAOGO
  • Département Médecine et Pharmacopée Traditionnelles/ Pharmacie (MEPHATRA-PH), Institut de Recherche en Sciences de la Santé (IRSS/CNRST), 03 BP 7192 Ouagadougou 03, Burkina Faso.
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Mohamed Bonewende BELEMLILGA
  • Mohamed Bonewende BELEMLILGA
  • Département Médecine et Pharmacopée Traditionnelles/ Pharmacie (MEPHATRA-PH), Institut de Recherche en Sciences de la Santé (IRSS/CNRST), 03 BP 7192 Ouagadougou 03, Burkina Faso.
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Adama KABORE
  • Adama KABORE
  • DépartementProductions Animales (DPA), Institut de l’Environnement et de Recherches Agricoles (INERA/ CNRST), Ouagadougou, Burkina Faso.
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Innocent Pierre GUISSOU
  • Innocent Pierre GUISSOU
  • Département Médecine et Pharmacopée Traditionnelles/ Pharmacie (MEPHATRA-PH), Institut de Recherche en Sciences de la Santé (IRSS/CNRST), 03 BP 7192 Ouagadougou 03, Burkina Faso.
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  •  Received: 19 August 2017
  •  Accepted: 06 November 2017
  •  Published: 29 November 2017

Abstract

Cassia sieberiana DC. (Caesalpiniaceae), Guiera senegalensis JF. Gmel (Combretaceae) and Excoecaria grahamii (Hochst) Pax. (Euphorbiaceae) are used in traditional medicine in Burkina Faso to treat gastro-intestinal parasites. Standard methods were used for phytochemical screening and to evaluate the in vitro anthelmintic activity of the aqueous extracts of the three (3) plants using the egg hatch test against Haemonchus contortus eggs. The phytochemical analysis revealed the presence of anthocyanosides, tannins, saponosides, reducing compounds, carbohydrates, flavonoids and triterpenic steroids in the extracts of the root bark of C. sieberiana and the leaves of C. sieberiana, G. senegalensis and E. grahamii. All extracts inhibited significantly (p< 0.05) the eggs hatch of H. contortus. At the concentration of 14.25 mg/mL, the percentages of inhibition varied from 60.33 ± 8.43 to 76.6 ± 4.91%. These results indicate that the studied plants possess anthelminthic activities and thus justify their use for the treatment of gastrointestinal parasites infections.
 
Key words: Anthelmintic activity, medicinal plants, phytochemical, in vitro, Haemonchus contortus, Burkina Faso.