African Journal of Pharmacy and Pharmacology
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Article Number - 2E27F1E40532


Vol.7(33), pp. 2333-2340 , September 2013
DOI: 10.5897/AJPP12.1276
ISSN: 1996-0816



Full Length Research Paper

Evaluation of wound healing activity of the polyherbal and Euphorbia hirta formulations


Kuldeep Ganju1* and A. K. Pathak2




1Principal, SIPTec, Gandhinagar, Bhopal, India.

2Department of Pharmacy, B.U., Bhopal, India.


Email: kuldeepganju@yahoo.com






 Accepted: 26 July 2013  Published: 08 September 2013

Copyright © 2013 Author(s) retain the copyright of this article.
This article is published under the terms of the Creative Commons Attribution License 4.0


Evaluation of wound healing activity of polyherbal and Euphorbia hirta formulations was done. The study aimed at preparing a polyherbal formulation containing equal proportions of ethanolic extract of Tridax procumbensEuphorbia hirtaEclipta alba, dried rhizome ofCurcuma longa and gel of Aloe barbadensis. Excision wound, incision wound and granulaoma wound models were studied. In excision wound model it was observed that 100% wound healing was found on 12th day of the experiment on application of 10% polyherbal ointment and 100% wound contraction was found on 16th day of application of 10% ointment of E. hirta. The results were statistically compared with control and found significant. Similarly, period of epithelilization, biochemical parameters and weight of granuloma tissues showed better results in the treated groups when compared with control in the studied wound models. Thus it is concluded that topical and oral formulations were found to contain significant wound healing activity.           

 

Key words: Excision wound, incision wound, granuloma.


APA (2013). Evaluation of wound healing activity of the polyherbal and Euphorbia hirta formulations. African Journal of Pharmacy and Pharmacology, 7(33), 2333-2340.
Chicago Kuldeep Ganju and A. K. Pathak. "Evaluation of wound healing activity of the polyherbal and Euphorbia hirta formulations." African Journal of Pharmacy and Pharmacology 7, no. 33 (2013): 2333-2340.
MLA Kuldeep Ganju and A. K. Pathak. "Evaluation of wound healing activity of the polyherbal and Euphorbia hirta formulations." African Journal of Pharmacy and Pharmacology 7.33 (2013): 2333-2340.
   
DOI 10.5897/AJPP12.1276
URL http://academicjournals.org/journal/AJPP/article-abstract/2E27F1E40532

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