Biotechnology and Molecular Biology Reviews
Subscribe to BMBR
Full Name*
Email Address*

Article Number - 614E1D410892


Vol.2(1), pp. 1-13 , February 2007

ISSN: 1538-2273



Review

Molecular strategies of microbia adaptation to xenobiotics in natural environment


Olusola Abayomi   Ojo




Department of Microbiology, Lagos State University, Badagry Expressway, P.O. BOX 12142 Ikeja, Lagos, Nigeria


Email: solayom@yahooo.com






 Accepted: 28 November 2006  Published: 28 February 2007

Copyright © 2007 Author(s) retain the copyright of this article.
This article is published under the terms of the Creative Commons Attribution License 4.0


The unprecedented population increase and industrial development during the twentieth century has increased conventional solid and liquid waste pollutants to critical levels as well as produced a range of previously unknown strange synthetic chemicals for which society was unprepared. Increasing pollution of the environment by xenobiotic compounds has provoked the need for understanding the impact of toxic compounds   on microbial populations, the catabolic degradation pathway of xenobiotics and upgrade in bioremediation processes. Adaptation of native microbial community to xenobiotic substrates is thus   crucial for any mineralization to occur in polluted environment. Enzymes which catalyze the biodegradation of xenobiotics   are often produced by induction process and this subsequently determine the acclimation time to xenobiotic substrates. Microbial degraders are adapted to xenobiotic substrates via various genetic mechanisms that subsequently determine the evolution of functional degradative pathways. The ultimate goal of these genetic mechanisms is to creating novel genetic combinations in microorganisms that facilitates mineralization of xenobiotics. Moreover, recent development of high-throughput molecular techniques such as polymerase chain reaction (PCR), microarrays and metagenomic libraries have helped to uncover issues of genetic diversity among environmentally relevant microorganisms as well as identification of new functional genes which would enhance pollution abatement management in the twenty-first century.

                                                                                                                                                   

Key words: Biodegradation, bioremediation, DNA, metagenomics, microarrays and xenobiotics.


APA (2007). Molecular strategies of microbia adaptation to xenobiotics in natural environment. Biotechnology and Molecular Biology Reviews, 2(1), 1-13.
Chicago Olusola Abayomi   Ojo. "Molecular strategies of microbia adaptation to xenobiotics in natural environment." Biotechnology and Molecular Biology Reviews 2, no. 1 (2007): 1-13.
MLA Olusola Abayomi   Ojo. "Molecular strategies of microbia adaptation to xenobiotics in natural environment." Biotechnology and Molecular Biology Reviews 2.1 (2007): 1-13.
   
DOI
URL http://academicjournals.org/journal/BMBR/article-abstract/614E1D410892

Subscription Form