International Journal of
Medicine and Medical Sciences

  • Abbreviation: Int. J. Med. Med. Sci.
  • Language: English
  • ISSN: 2006-9723
  • DOI: 10.5897/IJMMS
  • Start Year: 2009
  • Published Articles: 502

Full Length Research Paper

External application of moisture exposed burn ointment for phlebitis: A meta-analysis of randomized controlled trials

Lian Liu
  • Lian Liu
  • Nursing School, Southwest Medical University, China.
  • Google Scholar
Song Wei Su
  • Song Wei Su
  • Basic School, Guangzhou University of Chinese Medicine, China.
  • Google Scholar
Ping Zhou
  • Ping Zhou
  • Department of Oncology, the Affiliated Hospital of Southwest Medical University, China.
  • Google Scholar
Ru Song
  • Ru Song
  • Department of Orthopedic, the Affiliated Hospital of Southwest Medical University, China.
  • Google Scholar
Hong Yan Sun
  • Hong Yan Sun
  • Nursing School, Southwest Medical University, China.
  • Google Scholar


  •  Received: 26 April 2017
  •  Accepted: 13 September 2017
  •  Published: 31 December 2017

Abstract

To evaluate the therapeutic effects of moisture exposed burn ointment (MEBO) on phlebitis, seven electronic databases where checked until September, 2016 for randomized controlled trials (RCTs) of MEBO on phlebitis. Risk of bias was assessed using Cochrane handbook guidelines. Thirty eight randomized controlled trials met the inclusion criteria in which the aggregated results indicated that comparison revealed significant differences in total effectiveness rate of MEBO versus conventional therapy (RR=1.27, 95% confidence interval [CI]=1.06, 1.52, and P=0.009), and there were some beneficial evidence regarding the effects on reducing incidence of phlebitis MEBO versus conventional therapy in preventing phlebitis (RR=2.73, 95% confidence interval [CI]=1.94, 3.85, and P<0.00001). The evidence that MEBO is an effective treatment for phlebitis is encouraging, but not conclusive due to the low methodological quality of the RCTs. Therefore, more high-quality RCTs with larger sample sizes are required.
 
Key words: External application of moisture exposed burn ointment, prevention and (or) treatment, phlebitis.