International Journal of Medicine and Medical Sciences
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Article Number - DE9979A14


Vol.5(9), pp. 409-413 , September 2013
DOI: 10.5897/IJMMS09.294
ISSN: 2006-9723



Antifungal activity of some species of marine sponges (class: Demospongiae) of the palk bay, southeast coast of India



Chendur Palpandi
  • Chendur Palpandi
  • Centre of Advanced study in Marine Biology, Annamalai University, Parangipettai – 608 502, India.
  • Google Scholar
Suganthi Krishnan
  • Suganthi Krishnan
  • Centre of Advanced study in Marine Biology, Annamalai University, Parangipettai – 608 502, India.
  • Google Scholar
Ganavel Ananthan
  • Ganavel Ananthan
  • Centre of Advanced study in Marine Biology, Annamalai University, Parangipettai – 608 502, India.
  • Google Scholar







 Accepted: 31 May 2013  Published: 11 September 2013

Copyright © 2013 Author(s) retain the copyright of this article.
This article is published under the terms of the Creative Commons Attribution License 4.0


 

Nine species of sponges (Orders: Keratosida, Hadromerida, Haplosclerida and Poecilosclerida) of the class Demospongiae were tested for antifungal activity. In general, only trace and moderate activity was observed against the fungal pathogens tested. However, the encrusting Keratosida sponges depicted strong antifungal activity than the other sponges. In vitro antifungal activity of sponge extracts was determined against six species of pathogenic fungi (Aspergillus niger, Aspergillus flavus, Aspergillus fumigatus, Penicillium sp., Candida albicans, Cryptococcus sp.). Stock cultures of fungi were maintained in Czapex Dox agar. On the surface of the medium, discs inoculated with the extract (20 µl/6 mm disc) were placed. The inhibition zone was measured after 72 h of incubation and the antifungal activity has been expressed as inhibition zone in mm. In the present investigation, four solvents viz; ethanol, methanol, acetone and chloroform were used to obtain crude extracts from sponges. Of these, only chloroform and ethanol extracts showed activity against the fungi. There was higher activity against Cryptococcus sp. (10 mm) in the crude extracts of chloroform and minimum activity against A. fumigatus (5 mm) in the crude extract of ethanol. From the present study, it could be understood that the sponges might be used for the extraction of useful drugs that have antifungal activity against the important human pathogenic fungal species. Besides, the result of the present study is providing baseline data for the future researches in this line of work and is also throwing more light on the use of sponges by the pharmaceutical technologies for the extraction of useful drugs.

 

Key words: Demospongiae, solvents, antifungal activity, Palk Bay.

 

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APA (2013). Antifungal activity of some species of marine sponges (class: Demospongiae) of the palk bay, southeast coast of India. International Journal of Medicine and Medical Sciences, 5(9), 409-413.
Chicago Chendur Palpandi, Suganthi Krishnan and Ganavel Ananthan. "Antifungal activity of some species of marine sponges (class: Demospongiae) of the palk bay, southeast coast of India." International Journal of Medicine and Medical Sciences 5, no. 9 (2013): 409-413.
MLA Chendur Palp, et al. "Antifungal activity of some species of marine sponges (class: Demospongiae) of the palk bay, southeast coast of India." International Journal of Medicine and Medical Sciences 5.9 (2013): 409-413.
   
DOI 10.5897/IJMMS09.294
URL http://academicjournals.org/journal/IJMMS/article-abstract/DE9979A14

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