African Journal of Bacteriology Research
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Article Number - 14A127962796


Vol.9(1), pp. 1-8 , January 2017
DOI: 10.5897/JBR2016.0224
ISSN: 2006-9871



Full Length Research Paper

Antimicrobial resistance pattern of bacterial isolates from different clinical specimens in Southern Ethiopia: A three year retrospective study



Anteneh Amsalu*
  • Anteneh Amsalu*
  • Department of Medical Microbiology, College of Medicine and Health Sciences, School of Biomedical and Laboratory Sciences, University of Gondar, Ethiopia.
  • Google Scholar
Zeleke Geto
  • Zeleke Geto
  • Ethiopian Public Health Institute, National Research and Reference Laboratory for Clinical Chemistry, Addis Ababa, Ethiopia.
  • Google Scholar
Demissie Asegu
  • Demissie Asegu
  • Department of Medical Laboratory Science, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia.
  • Google Scholar
Setegn Eshetie
  • Setegn Eshetie
  • Department of Medical Microbiology, College of Medicine and Health Sciences, School of Biomedical and Laboratory Sciences, University of Gondar, Ethiopia.
  • Google Scholar







 Received: 30 September 2016  Accepted: 15 November 2016  Published: 31 January 2017

Copyright © 2017 Author(s) retain the copyright of this article.
This article is published under the terms of the Creative Commons Attribution License 4.0


Emergence of antimicrobial resistance is a major public health problem worldwide, particularly in developing countries. The effectiveness of currently available antibiotics is decreasing as a result of increasing resistant strains among clinical isolates. The aim of this study was to determine the antimicrobial resistance pattern of bacterial isolate from different clinical specimens at Hawassa University Referral Hospital. A retrospective data (from January 2012 to December 2014) of patients registered at microbiology record book were reviewed. Age, sex, type of clinical specimen, type of bacterial isolate and antimicrobial resistance pattern were extracted using data extraction format. Data were analyzed using SPSS version 16 software. A total of 143 bacterial isolates were collected from clinical specimens such as: urine (63; 44%), ear discharge (26; 18.2%), pus (25; 17.5%), stool (12; 8.4%), nasal swab (12; 8.4%), genital swab (3; 2.1%) and cerebrospinal fluid (2; 1.4%). The predominant bacterial isolates were E. coli (35; 24.5%) followed by S. aureus (31; 21.7%) and Klebsiella species (21; 14.7%). Greater than half percent of resistance were observed for ampicilin, cotrimoxazole, penicillin G, chloramphenicol, gentamicin, norfloxacin and oxacilin. Moreover, MDR was observed in 127 (88.8%) of the isolates. High prevalence of multi-drug resistant bacteria was observed in this study. Therefore, resistance surveillance studies should be conducted to develop local antibiogram data, for choosing the best antimicrobial therapy.

Key words: Antibiotic resistance, bacteria isolate, clinical specimen, Ethiopia. 

Abbreviation:

AMR, Antimicrobial resistance; CLSI, Clinical Laboratory Standards Institute; CoNS, coagulase negative Staphylococci; CSF, cerebrospinal fluid; MDR, multi-drug resistance; UTIs, Urinary tract infections. 


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APA Amsalu, A., Geto, Z., Asegu, D., & Eshetie, S. (2017). Antimicrobial resistance pattern of bacterial isolates from different clinical specimens in Southern Ethiopia: A three year retrospective study. African Journal of Bacteriology Research, 9(1), 1-8.
Chicago Anteneh Amsalu, Zeleke Geto, Demissie Asegu and Setegn Eshetie. "Antimicrobial resistance pattern of bacterial isolates from different clinical specimens in Southern Ethiopia: A three year retrospective study." African Journal of Bacteriology Research 9, no. 1 (2017): 1-8.
MLA Anteneh Amsalu, et al. "Antimicrobial resistance pattern of bacterial isolates from different clinical specimens in Southern Ethiopia: A three year retrospective study." African Journal of Bacteriology Research 9.1 (2017): 1-8.
   
DOI 10.5897/JBR2016.0224
URL http://academicjournals.org/journal/JBR/article-abstract/14A127962796

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