Journal of
Bioinformatics and Sequence Analysis

  • Abbreviation: J. Bioinform. Seq. Anal.
  • Language: English
  • ISSN: 2141-2464
  • DOI: 10.5897/JBSA
  • Start Year: 2009
  • Published Articles: 42

Full Length Research Paper

A computational technique for prediction and visualization of promoter regions in long human genomic sequences

Q. M. Alfred1*, K. Bishayee1, P. Roy2 and T. Ghosh3
  1University Institute of Technology, University of Burdwan, West Bengal, India 713104 2Department of Biotechnology, University of Burdwan, West Bengal, India, 713104 3Burdwan Medical College and Hospital, West Bengal, India.
Email: [email protected]

  • Article Number - 8A1E5372273
  • Vol.1(1), pp. 011-016, May 2009
  •  Accepted: 29 April 2009
  •  Published: 29 May 2009

Abstract

 

This communication proposes a simple algorithm with high specificity and sensitivity for determining promoter regions in human genomic sequences. This method relies upon non-redundant and experimentally verified promoter data sets form Eukaryotic Promoter Database (EPD) as training parameters. This technique predicts and computationally satisfies the promoter regions in the NCBI annotated database around gene sequences.  

 

Keywords: Promoter, CpG islands, transcription start site (TSS), discrete fourier transform/ fast fourier transform (DFT/FFT).

 

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