Journal of Biophysics and Structural Biology
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Article Number - 0E5387640425


Vol.5(1), pp. 10-18 , July 2013
DOI: 10.5897/JBSB2012.005
ISSN: 2141-2200



Full Length Research Paper

Changes in airway resistance with cumulative numbers of cigarettes smoked


Almaasfeh Sultan




Physics Department College of Science, Al Hussein Bin Talal University, Jordan.


Email: almaasfeh@ahu.edu.jo






 Accepted: 07 December 2012  Published: 31 July 2013

Copyright © 2013 Author(s) retain the copyright of this article.
This article is published under the terms of the Creative Commons Attribution License 4.0


This work was performed with smokers of Virginia tobacco cigarettes without taking into consideration brand or type of cigarettes. An experimental study was conducted for the variation of cigarettes number and the increments in airway resistance for both normal and respiratory disordered subjects using body plethysmograph for testing individuals. Seventeen (17) nonsmokers and ten smokers were studied. The investigation evaluated respiratory function in both smokers and nonsmokers: their airway resistances were recorded, and relationships between height, weight and age were documented. The findings reveal that smoking of higher numbers of self-reported cumulative cigarettes was associated with higher airway resistance and higher total airway resistance. Comparisons of age, height and weight versus airway resistance revealed only slight changes in comparison to those associated with cumulative lifetime cigarette consumption.  
 
Key words: Air way resistance, total air way resistance, plethysmography, normal and disordered respiratory system.

Abbreviation:

VTG, Value by body plethysmograph; VC, vital capacity;  Lit/sec,liter/second; FVC, forced vital capacity; PFT, pulmonary function test;  FEV1,forced expiratory volume in one sec; Raw, airway resistance; Rawt, total airway resistance; PA, alveolar pressure; = Vdot; Flowrate, volume/second; Lit, Liter; Pp, plethysmography pressure; No, number;  Pt, patient;  Ht, height ; Wt, weight;  Cig/day,cigarette per day; Yr, year; Total no of cig, total number of cigarette; R, correlation factor.


Al Kadri FM (1998). Changes in respiratory muscle efficiency upon change in airway resistance and compliance. A thesis submitted to the council of the College of Education, Al Mustansiriyeh University.
 
Al Sa'ady AF (1997). Variability of human respiratory compliance and air way resistance. A thesis submitted to the council of the College of Education of Al Mustansiriyah University.
 
Almaasfeh Sultan (1995). Indirect Method For Determining Work of Breathing Upon Change in Resistance. Athesis submitted to the council of college of education ALmustansiriyah University.
 
Banner MJ, Jaeger MJ, Kirby RR (1994). Components of the work of breathing, critical care medicine, (22) no.3 Williams and Wilkins.
 
Beydon L, Chasse M, Harf A, Le Maire F (1988). Inspiratory work of breathing during spontaneous ventilation using demand valves and continuous flow system. Am. Rev. Respiratory. Dis. 138: 300-304.
http://dx.doi.org/10.1164/ajrccm/138.2.300
PMid:3057961
 
Coates AL, Vallinis P, Mallahoo K, Seddon P, and Davis GM (1994). Pulmonary impedance as an index of severity and mechanism of neonatal lung disease, Pediatric pulmonology Wiley-LISS Inc.. 17:41-49.
 
Fitting JW (1992). Fatigue des muscles respiratoires. (Schweiz Med.Wschr. 122: 302-306).
PMid:1546280
 
Fitting JW (1994). Role des muscles respiratoires dans le Sevrage de la ventilation mecanique. (Achweiz med. Wochenschr. 124: 215-220.
 
Guyton AG, Hall JE (2009). Text book of medical physiology, 13th edition. (W.B. Saunder's Company).
 
Goldman MD, Grimby G, Mead J (1976). Mechanical work of breathing derived from rib cage an abdominal. V-p- portioning. J. Appl. Physiol. 41(5).
 
Jason PKirkness,Vidya Krishnan, Susheel P, Patil, Hartmut Schneider (2006). Upper airway obstruction in snoring and upper airway resistance syndrome Prog.RespirRes.Basel,Karger (35) pp. 79 – 89 Randerath Wj, Sanner BM,Somer VK eds Sleep apnea.
 
Macklem PT (1980). Respiratory muscles: The vital pump. Chest, 78:5 Nov.
http://dx.doi.org/10.1378/chest.78.5.753
 
Martine Broetima, Nick HT tenHacken, Franke Volbeda, Monique E, Lodewijk MN, Hylkema DS, Postma WT (2009). Air way epithelial changes in smoking but not in ex-smoking asthmatics, PP 1-43 AJRCCM articles in press as doi:10.1164/rccm 2009 06-0828OC.
 
Mecklenburg JS, Latto IP, Alobaidi TAA, Swai EA, Mapeleson WW (1990). Excessive work of breathing during intermittent mandatory ventilation, Anesth, (58), 1048-1054).
 
Mecklenburg JS, Alobaidi TAA, Mapeleson WW (1992). A model lung with direct representation of the respiratory muscle activity. BJ. Anaesthesia 68, 603.
http://dx.doi.org/10.1093/bja/68.6.603
 
Mushin WW, Rendell-Backer L, Thomson, Peter W, Mapleson WW, Hillard EK (1980). Automatic ventilation of the lungs, 3rd edition.(Blackwell Scientific Publications).
 
Pengelly LD, Rebuck AS, Campbell EJM (1974). Loaded breathing, Churcheill Livingstone.
 
Polese G, Rossi A, Appendini Li, Brandi G, Bates JHT, Brandolese R (1991). Partitioning of respiratory mechanism in mechanically ventilated patients. (J. appl. Physiol. 71 (6), (2425-2433).
PMid:1778942
 
Shapiro BA, Kak Marck, Robert MM., Cane, Roy D, Perruzi, William T, Hauptman David (1991). Clinical application of respiratory care, 4th edition, (Mosby Year book).
 
Stephan J, LaiFook, Yih-Loong Lai (2005). Airway resistance due to alveolar gas compression measured by barometric plethysmography in mice. J. Appl. Physiol. 98: 2204–2218.
http://dx.doi.org/10.1152/japplphysiol.00869.2004
PMid:15677740
 
Sykes MK, Vickers MD (1970). Principle of measurement for anaesthetists, Blackwell Scientific publication, 2nd printing.
 
Tortora D (2006). Principles of anatomy and physiology 11th Edition, John Wiley and sons.inc.
PMCid:PMC2361320

 


APA (2013). Changes in airway resistance with cumulative numbers of cigarettes smoked. Journal of Biophysics and Structural Biology, 5(1), 10-18.
Chicago Almaasfeh Sultan. "Changes in airway resistance with cumulative numbers of cigarettes smoked." Journal of Biophysics and Structural Biology 5, no. 1 (2013): 10-18.
MLA Almaasfeh Sultan. "Changes in airway resistance with cumulative numbers of cigarettes smoked." Journal of Biophysics and Structural Biology 5.1 (2013): 10-18.
   
DOI 10.5897/JBSB2012.005
URL http://academicjournals.org/journal/JBSB/article-abstract/0E5387640425

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