Journal of Clinical Immunology and Immunopathology Research
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Article Number - 9E945915428


Vol.2(1), pp. 9-14 , April 2010

ISSN: 1996-0816



Full Length Research Paper

Benign monoclonal gammopathy in a dog exhibiting a low antibody titer to Ehrlichia canis



Ng Stephanie
  • Ng Stephanie
  • Department of Pathobiology, University of Guelph, Guelph, Ontario, Canada N1G 2W1, Canada.
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Sophia Lim
  • Sophia Lim
  • Department of Pathobiology, University of Guelph, Guelph, Ontario, Canada N1G 2W1, Canada.
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Allison Daub
  • Allison Daub
  • Campus Estates Animal Hospital, Guelph, Ontario, Canada N1G 3A2, Canada.
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Surinder S. Saini
  • Surinder S. Saini
  • Department of Pathobiology, University of Guelph, Guelph, Ontario, Canada N1G 2W1, Canada.
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Kaushik K. Azad
  • Kaushik K. Azad
  • Department of Pathobiology, University of Guelph, Guelph, Ontario, Canada N1G 2W1, Canada.Department of Molecular and Cell Biology, University of Guelph, Guelph, Ontario, Canada N1G 2W1, Canada.
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 Accepted: 26 February 2010  Published: 30 April 2010

Copyright © 2010 Author(s) retain the copyright of this article.
This article is published under the terms of the Creative Commons Attribution License 4.0


The occurrence of a remarkable benign g-monoclonal gammopathy in a 2.5-year-old intact male bichon frise dog, secondary to acute Ehrlichia canis infection, with no travel history outside of Ontario. Exceptionally high levels of serum IgG (104.0 g/L) as a result of benign monoclonal gammopathy were noted during the disease state that returned to normal subsequent to recovery. Treatment with doxycyline and prednisone resulted in complete recovery and disappearance of the monoclonal gammopathy. In conclusion, such a recovery from monoclonal gammopathy due to infection is indeed promising since very high serum IgG concentrations can be brought back to physiological levels by therapeutic intervention.

 

Key words: Dog, benign monoclonal gammopathy, Ehrlichia canis.


APA (2010). Benign monoclonal gammopathy in a dog exhibiting a low antibody titer to Ehrlichia canis. Journal of Clinical Immunology and Immunopathology Research, 2(1), 9-14.
Chicago Ng Stephanie, Sophia Lim, Allison Daub, Surinder S. Sainiand Kaushik K. Azad, . "Benign monoclonal gammopathy in a dog exhibiting a low antibody titer to Ehrlichia canis." Journal of Clinical Immunology and Immunopathology Research 2, no. 1 (2010): 9-14.
MLA Ng Stephanie, et al. "Benign monoclonal gammopathy in a dog exhibiting a low antibody titer to Ehrlichia canis." Journal of Clinical Immunology and Immunopathology Research 2.1 (2010): 9-14.
   
DOI
URL http://academicjournals.org/journal/JCIIR/article-abstract/9E945915428

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