Journal of Clinical Medicine and Research
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Article Number - 8DE509248691


Vol.6(6), pp. 16-21 , November 2014
DOI: 10.5897/JCMR2014.0249
ISSN: 2141-2235



Full Length Research Paper

Vaginal colonization and resistance profile of group B Streptococcus among pregnant women in Yaoundé Gynecology, Obstetric and Pediatric Hospital in Cameroon



Chatt Adawaye
  • Chatt Adawaye
  • Department of Microbiology, Virology, Immunology, Parasitology and Hematology, Faculty of Medicine and Biomedical Science, University of Yaound, Cameroon. University of Science and Technology of Abeche, Chad.
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Toukam Michel
  • Toukam Michel
  • Department of Microbiology, Virology, Immunology, Parasitology and Hematology, Faculty of Medicine and Biomedical Science, University of Yaound, Cameroon. Laboratory of bacteriology, Yaound General Hospital, Cameroon.
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Assam Jean Paul*
  • Assam Jean Paul*
  • Laboratory of Microbiology, Department of Biochemistry, Faculty of Science, University of Douala, Cameroon.
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Nkoa Thrse
  • Nkoa Thrse
  • Department of Microbiology, Virology, Immunology, Parasitology and Hematology, Faculty of Medicine and Biomedical Science, University of Yaound, Cameroon.
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Gonsu Hortense
  • Gonsu Hortense
  • Department of Microbiology, Virology, Immunology, Parasitology and Hematology, Faculty of Medicine and Biomedical Science, University of Yaound, Cameroon.
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M. Koanga
  • M. Koanga
  • Laboratory of Microbiology, Department of Biochemistry, Faculty of Science, University of Douala, Cameroon.
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Koulla Shiro Sinata
  • Koulla Shiro Sinata
  • Department of Microbiology, Virology, Immunology, Parasitology and Hematology, Faculty of Medicine and Biomedical Science, University of Yaound, Cameroon.
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 Received: 18 February 2014  Accepted: 30 September 2014  Published: 30 November 2014

Copyright © 2014 Author(s) retain the copyright of this article.
This article is published under the terms of the Creative Commons Attribution License 4.0


In order to obtain reliable data on vaginal carriage of Streptococcus agalactiae in pregnant women and to formulate a prevention program of neonatal Group B Streptococcus (GBS) disease, we carried out a prospective cross sectional study for 6 months. The general objective of the study was to evaluate the prevalence of vaginal carriage and the resistance profile of GBS. The study involved 142 pregnant women presenting for antenatal care in Yaoundé Gynecology-Obstetric and Pediatric Hospital (YGOPH). Participants were interviewed using a standard structure questionnaire. Low vaginal swabs were collected and cultured on specific media. A presumptive identification of isolates was made using standard bacteriological methods. Confirmative identification of Group B Streptococcus was done and antimicrobial sensitivity testing was performed. Among the 142 pregnant women GBS colonization was confirmed in 11 (7.7%). The rate of carriage was 3.8% in the first trimester, 7% in the second trimester and 11.1% in the third trimester. The predominant germ was Candida albicans with a frequency of 45.2% among the germs found in monomicrobial culture and Gardnerella vaginalis (77.8%) among the germs in polymicrobial culture, followed by Candida spp (11.8%), S. agalactiae (8.6%) and Escherichia coli (4.3%). The result of antimicrobial sensitivity testing showed that all the GBS strains were sensitive to major antibiotics drugs tested. The highest rates of resistance were found with gentamycin (100%) and Cefuroxim (81.8%). The vaginal carriage of GBS among pregnant women is still high. Thus, well-planned, prospective studies will be necessary to fully appreciate the magnitude of the problem of GBS in our hospitals.

 

Key words: Group B Streptococcus, neonatal infections, antibiotic, low vaginal swabs.

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APA Adawaye, C., Michel, T., Paul*, A. J., Thérèse, N., Hortense, G., Koanga, M., & Sinata, K. S. (2014). Vaginal colonization and resistance profile of group B Streptococcus among pregnant women in Yaoundé Gynecology, Obstetric and Pediatric Hospital in Cameroon. Journal of Clinical Medicine and Research, 6(6), 16-21.
Chicago Chatt&e Adawaye, Toukam Michel, Assam Jean Paul, Nkoa Th&erèse,Gonsu Hortense, M. Koanga and Koulla Shiro Sinata. "Vaginal colonization and resistance profile of group B Streptococcus among pregnant women in Yaoundé Gynecology, Obstetric and Pediatric Hospital in Cameroon." Journal of Clinical Medicine and Research 6, no. 6 (2014): 16-21.
MLA Chatteacute; Adawaye, et al. "Vaginal colonization and resistance profile of group B Streptococcus among pregnant women in Yaoundé Gynecology, Obstetric and Pediatric Hospital in Cameroon." Journal of Clinical Medicine and Research 6.6 (2014): 16-21.
   
DOI 10.5897/JCMR2014.0249
URL http://academicjournals.org/journal/JCMR/article-abstract/8DE509248691

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