Journal of
Clinical Pathology and Forensic Medicine

  • Abbreviation: J. Clin. Pathol. Forensic Med.
  • Language: English
  • ISSN: 2141-2405
  • DOI: 10.5897/JCPFM
  • Start Year: 2010
  • Published Articles: 28

Review

Angiogenesis in thyroid malignant neoplasm: State of the art and advances of the modern digital pathology and nanotechnology

Matvey Vladimir Sprindzuk
United Institute of Informatics Problems, National Academy of Sciences of Belarus, Minsk, Belarus. 
Email: [email protected], [email protected]

  • Article Number - 4DE7B982083
  • Vol.1(3), pp. 16 - 34, November 2010
  •  Accepted: 13 September 2010
  •  Published: 30 November 2010

Abstract

It is well known that both radiation and genetic factors are interconnected and significantly impact the morbidity of thyroid cancer and that is why Belarus has the highest incidence of that malignancy. Author describes statistical data, classification of angiogenesis and thyroid cancer, typical pathological features of malignant thyroid diseases relating to the vascular network. Nanotechnology developed for molecular imaging, differential diagnosis and drug delivery applied for thyroid cancer investigation and the free open-source image processing software applications designed for the quantitative evaluation of histological samples are discussed.

 

Key words: Thyroid gland, angiogenesis, cancer, malignancy, image processing, tumor expansion, nanotechnology, radiation effects.

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