Journal of
Clinical Pathology and Forensic Medicine

  • Abbreviation: J. Clin. Pathol. Forensic Med.
  • Language: English
  • ISSN: 2141-2405
  • DOI: 10.5897/JCPFM
  • Start Year: 2010
  • Published Articles: 28

Full Length Research Paper

Prevalent latent adenocarcinoma of the prostate in forensic autopsies

Wei Tian
  • Wei Tian
  • Department of Forensic Medicine, Tokai University School of Medicine, Isehara, Kanagawa, Japan. 2International Science and Technology Cooperation Base of Geriatric Medicine, North China University of Science and Technology, Tangshan, China.
  • Google Scholar
Motoki Osawa*
  • Motoki Osawa*
  • Department of Forensic Medicine, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
  • Google Scholar


  •  Received: 20 April 2015
  •  Accepted: 05 June 2015
  •  Published: 31 July 2015

Abstract

In the aging society, elder people commonly suffer cancer, which is associated with increased rates of fractures due to osteoporosis from cancer. In the present study, the prevalence of prostatic cancer, so-called “latent adenocarcinoma”, is investigated among forensic autopsy cases. Retrospective histo-pathology was performed on 114 subjects (61.8 ± 13.3 years old). Forth-four specimens (38.6%) harbored carcinomas with Gleason combined scores ranging from 3 to 9. The detection rate increased in accordance with age, in which the highest rate (8/13, 61.5%) was evident in the group of ≥ 80 years of age. However, no significant associations were apparent to age (P = 0.13) or body mass index (P = 0.36). Majority (34, 77.2%) displayed solitary lesions that were located mainly in the peripheral zone. Advanced capsular invasion was evident in five cases. The prostate that is not familiar to forensic pathologists should be examined in extrinsic fractures of the elderly because cancer might affect injury severity.

 

Key words: Forensic pathology, prostate, gleason score, histopathology, elderly.