Journal of Infectious Diseases and Immunity
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Article Number - DF707E55786


Vol.5(3), pp. 24-28 , September 2013
DOI: 10.5897/JIDI2013.0118
ISSN: 2141-2375



Full Length Research Paper

Analysis of Beta-lactamase production and Antibiotics resistance in Staphylococcus aureus strains



Torimiro N
  • Torimiro N
  • Department of Microbiology, Obafemi Awolowo University, Ile-Ife, Nigeria.
  • Google Scholar
Moshood AA
  • Moshood AA
  • Department of Microbiology, Obafemi Awolowo University, Ile-Ife, Nigeria.
  • Google Scholar
Eyiolawi SA
  • Eyiolawi SA
  • Department of Botany and Microbiology, University of Ibadan, Ibadan, Nigeria.
  • Google Scholar







 Published: 30 September 2013

Copyright © 2013 Author(s) retain the copyright of this article.
This article is published under the terms of the Creative Commons Attribution License 4.0


The antibiotic susceptibility profile and the association of β-lactamase production to antibiotic resistance in Staphylococcus aureus strains were analysed. The disk diffusion antibiotic susceptibility pattern was conducted on S. aureus strains cultured from clinical specimens using standard bacteriological methods. The β-lactamase production was assayed using the modified Perret’s iodometric assay and data were statistically analysed. Of the 107 S. aureus isolates identified, 77 (72%) of the isolates were multi-drug resistant and 75 (70.1%) produced β-lactamase.  β-lactamase production and resistance to  amoxicillin, amoxicillin/clavulanic acid (augmentin) and ceftriaxone resistance was significant (p-value< 0.05). The study suggests strict infection control measures and encouragement of prudent antibiotic use.

 

Key words: Staphylococcus aureus, Antibiotics, Beta-lactamase, Resistance

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APA Torimiro, N., Moshood, A. A., & Eyiolawi, S. A. (2013). Analysis of Beta-lactamase production and Antibiotics resistance in Staphylococcus aureus strains. Journal of Infectious Diseases and Immunity, 5(3), 24-28.
Chicago Torimiro N, Moshood AA and Eyiolawi SA. "Analysis of Beta-lactamase production and Antibiotics resistance in Staphylococcus aureus strains." Journal of Infectious Diseases and Immunity 5, no. 3 (2013): 24-28.
MLA Torimiro N, Moshood AA and Eyiolawi SA. "Analysis of Beta-lactamase production and Antibiotics resistance in Staphylococcus aureus strains." Journal of Infectious Diseases and Immunity 5.3 (2013): 24-28.
   
DOI 10.5897/JIDI2013.0118
URL http://academicjournals.org/journal/JIDI/article-abstract/DF707E55786

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