Journal of Medical Genetics and Genomics
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Article Number - AC79B545778


Vol.2(2), pp. 18-23 , April 2010

ISSN: 2141-2278



Case Report

Co-inheritance ααα anti 3.7 triplication with hemoglobin D/β0 thalassemia: A case report from South-west Iran


B. Keikhaei1, H. Galehdari2 and B. Salehi3




1Research center for Thalassemia and Hemoglobinopathy of Jondishapour University of Medical Science, Ahvaz, Iran.

2Department of Genetics, Shahid Chamran University, Research Center for Thalassemia and Hemoglobinopathy Ahwaz, Iran.

3Shafa Hospital, Kerman, Iran.


Email: keikhaeib@yahoo.com






 Accepted: 16 February 2010  Published: 30 April 2010

Copyright © 2010 Author(s) retain the copyright of this article.
This article is published under the terms of the Creative Commons Attribution License 4.0


Hemoglobin D [Hb D] is the second most common hemoglobin variant in South west of Iran. It places in second position after hemoglobin S. So far up to present, from the genetic point of view, all cases of Hb D are hemoglobin Punjab. Hb D, in all forms, heterozygote, homozygote and compound heterozygote presents with mild anemia or completely asymptomatic that may be discovered accidentally. There was a case presentation of a child with genotype of Hb D/β0 thalassemia co-inherited with ααα anti 3.7 triplication and phenotype of moderate to severe anemia similar to thalassemia intermediate.

 

Key words: Hb D-Punjab, ααα anti 3.7 triplication, South west of Iran.


APA (2010). Co-inheritance ααα anti 3.7 triplication with hemoglobin D/β0 thalassemia: A case report from South-west Iran. Journal of Medical Genetics and Genomics, 2(2), 18-23.
Chicago B. Keikhaei, H. Galehdari and B. Salehi. "Co-inheritance ααα anti 3.7 triplication with hemoglobin D/β0 thalassemia: A case report from South-west Iran." Journal of Medical Genetics and Genomics 2, no. 2 (2010): 18-23.
MLA B. Keikhaei, H. Galehdari and B. Salehi. "Co-inheritance ααα anti 3.7 triplication with hemoglobin D/β0 thalassemia: A case report from South-west Iran." Journal of Medical Genetics and Genomics 2.2 (2010): 18-23.
   
DOI
URL http://academicjournals.org/journal/JMGG/article-abstract/AC79B545778

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