Journal of
Medical Laboratory and Diagnosis

  • Abbreviation: J. Med. Lab. Diagn.
  • Language: English
  • ISSN: 2141-2618
  • DOI: 10.5897/JMLD
  • Start Year: 2010
  • Published Articles: 60

Short Communication

Selenium levels in patients with schizophrenia

Simmi Kharb
  • Simmi Kharb
  • Department of Biochemistry, Pt.BDS PGIMS, M.D. University, Rohtak, India.
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Anjali Sharma
  • Anjali Sharma
  • Department of Biochemistry, Pt.BDS PGIMS, M.D. University, Rohtak, India.
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Vohra A. K
  • Vohra A. K
  • Department of Psychiatry, Pt.BDS PGIMS, M.D. University, Rohtak, India.
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Sanjiv Yadav
  • Sanjiv Yadav
  • Department of Chemistry, Pt.BDS PGIMS, M.D. University, Rohtak, India.
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Ishwar Singh
  • Ishwar Singh
  • Department of Chemistry, Pt.BDS PGIMS, M.D. University, Rohtak, India.
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  •  Accepted: 02 August 2010
  •  Published: 31 December 2010

Abstract

The present study was conducted with serum of twenty four patients of schizophrenia and twenty healthy volunteers; and selenium (Se) levels were determined by atomic absorption spectrophotometer. Serum Se levels were significantly increased in schizophrenia patients as compared to healthy controls.  Soil content of Se in Rohtak was found to be lower as compared to Haryana state soil Se levels. These findings suggest that low Se levels in schizophrenia patients and soil may have a role in pathogenesis of schizophrenia.

 

Key words: Selenium, schizophrenia, geographical distribution.