From the air dried aerial parts of Citrullus colocynthis, two new alkaloids namely, 2-(nonan-8-one)-(1H)-4-quinolone and 2-(Nonan-8-one) 4-methoxy-quinoline were isolated. Two flavonoids, (2S)-3\, 4\ -methylenedioxy -5, 7-dimethoxy flavan and hispidulin 7- (6 – E – β coumaroyl – β – D glucopyranoside) were also extracted and identified. The structures were established by conventional methods of analysis and confirmed by UV, IR, 1H and13CNMR, and mass spectra.
Key words: Citrullus colocynthis, cucurbitaceae, new quinoline, quinolone alkaloids, flavonoids.
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