Journal of Public Health and Epidemiology
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Article Number - E8018E863791

Vol.9(5), pp. 114-121 , May 2017
ISSN: 2141-2316

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Full Length Research Paper

Descriptive epidemiology of orofacial clefts in Africa using data from 46,502 Smile Train surgeries

Azeez Butali
  • Azeez Butali
  • Department of Oral Pathology, Radiology and Medicine, College of Dentistry, University of Iowa, Iowa City, IA, USA
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Keyla Pagán-Rivera
  • Keyla Pagán-Rivera
  • Division of Biostatistics and Research Design, Dows Research Institute, College of Dentistry, University of Iowa, Iowa City, IA, USA.
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Deborah V. Dawson
  • Deborah V. Dawson
  • Division of Biostatistics and Research Design, Dows Research Institute, College of Dentistry, University of Iowa, Iowa City, IA, USA.
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Ronald Munger
  • Ronald Munger
  • School of Public Health, Utah State University, United States
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Mekonen A. Eshete
  • Mekonen A. Eshete
  • Department of Burns and Plastic Surgery, Addis Ababa University, Addis Ababa, Ethiopia
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Wasiu L. Adeyemo
  • Wasiu L. Adeyemo
  • Department of Oral and Maxillofacial Surgery, University of Lagos, Lagos, Nigeria
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Peter A. Mossey
  • Peter A. Mossey
  • Department of Orthodontics, University of Dundee, Scotland, UK.
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 Received: 19 December 2016  Accepted: 16 February 2017  Published: 30 May 2017

Copyright © 2017 Author(s) retain the copyright of this article.
This article is published under the terms of the Creative Commons Attribution License 4.0

The descriptive epidemiology of orofacial clefts (OFC) is an essential prerequisite towards improved care, investigations into the etiology, and eventually prevention. In the present study the distribution of OFC in sub-Saharan Africa using post-surgical data from the Smile Train organization, was examined. Data from 46,502 individuals from Ethiopia (16,049), Nigeria (8,209), Uganda (5,138), Kenya (4,084), Tanzania (2,750), Congo DR (1,371), Zambia (1,319), Somalia (1,039), and a total of 6,543 individuals from another 26 African countries were available for analysis. Individuals without a cleft diagnosis and those who indicated non-black African as their racial group were excluded, and a total of 46,502 individuals were available for analysis. There was a significant difference in frequency between unilateral cleft lip and palate (70.24%) versus bilateral cleft lip and palate (29.76%; p < 0.0001), and these were also significant within each sex (p < 0.0001). In the database, there were more females (53.50%) with cleft palate only than males (46.50%) (p = 0.0002). Data reported here did not take into account infant mortality during the perinatal period. Nonetheless, this study provides estimates from the largest recorded body of data for clefts in the continent, therefore providing valuable information on the need for comprehensive cleft registries in Africa.


Key words: Clefts, Africa, epidemiology.

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APA Butali, A., Pagán-Rivera, K., Dawson, D. V., Munger, R., Eshete, M. A., Adeyemo, W. L. & Mossey, P. A. (2017). Descriptive epidemiology of orofacial clefts in Africa using data from 46,502 Smile Train surgeries. Journal of Public Health and Epidemiology, 9(5), 114-121.
Chicago Azeez Butali, Keyla Pag&an-Rivera, Deborah V. Dawson, Ronald Munger, Mekonen A. Eshete, Wasiu L. Adeyemo and Peter A. Mossey. "Descriptive epidemiology of orofacial clefts in Africa using data from 46,502 Smile Train surgeries." Journal of Public Health and Epidemiology 9, no. 5 (2017): 114-121.
MLA Azeez Butali, et al. "Descriptive epidemiology of orofacial clefts in Africa using data from 46,502 Smile Train surgeries." Journal of Public Health and Epidemiology 9.5 (2017): 114-121.

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