Journal of Pharmacognosy and Phytotherapy
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Article Number - C759C4762103


Vol.9(1), pp. 6-10 , January 2017
DOI: 10.5897/JPP2013.0261
ISSN: 2141-2502



Full Length Research Paper

Antibacterial and antifungal activities of leaf extracts of Phyllanthus amaru Schum and Thonn.



Senjobi, C.T.
  • Senjobi, C.T.
  • Tai Solarin College of Education, Omu-Ijebu, Ogun State, Nigeria.
  • Google Scholar
Ettu, A. O.
  • Ettu, A. O.
  • Tai Solarin College of Education, Omu-Ijebu, Ogun State, Nigeria.
  • Google Scholar
Otujo, C.O.
  • Otujo, C.O.
  • Tai Solarin College of Education, Omu-Ijebu, Ogun State, Nigeria.
  • Google Scholar







 Received: 14 January 2013  Accepted: 14 September 2016  Published: 31 January 2017

Copyright © 2017 Author(s) retain the copyright of this article.
This article is published under the terms of the Creative Commons Attribution License 4.0


The leaf extracts of Phyllanthus amarus Schum and Thonn. a common Western Nigerian weed, was investigated for phytochemical constituents and antimicrobial activities. Hexane extracts demonstrated the highest extraction of 59% followed by Acetone (57%) and water (48%). Saponins, tannins, alkaloid flavonoids, balsam, anthraquinones and phenols were extracted in an acidic medium. Twelve microorganisms (8 bacterial species and 4 fungal species) were investigated for antimicrobial activities. Generally, the fungal species showed lower minimum inhibitory concentration (MIC) than the bacterial species. The test organisms showed close susceptibility to the leaf extracts when compared with Bacitracin and Erythromycin. Generally, the combination of the leaf extract with either bacitracin or erythromycin alone demonstrated synergistic effect thus showing the potential benefit of combining these standard antibiotics with the leaf extracts of P. amarus for combating infections.

Key words: Phyllanthus amarus, leaf extracts, phytochemicals, antimicrobial property antibiotic.

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APA Senjobi, C.T., Ettu, A. O., & Otujo, C.O. (2017). Antibacterial and antifungal activities of leaf extracts of Phyllanthus amaru Schum and Thonn.. Journal of Pharmacognosy and Phytotherapy, 9(1), 6-10.
Chicago Senjobi, C.T., Ettu, A. O. and Otujo, C.O.. "Antibacterial and antifungal activities of leaf extracts of Phyllanthus amaru Schum and Thonn.." Journal of Pharmacognosy and Phytotherapy 9, no. 1 (2017): 6-10.
MLA Senjobi, et al. "Antibacterial and antifungal activities of leaf extracts of Phyllanthus amaru Schum and Thonn.." Journal of Pharmacognosy and Phytotherapy 9.1 (2017): 6-10.
   
DOI 10.5897/JPP2013.0261
URL http://academicjournals.org/journal/JPP/article-abstract/C759C4762103

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