Prevalence of falciparum malaria among patients attending University of Agriculture Makurdi Clinic, Nigeria, was determined on 318 patients from June to August, 2013. After informed consent of patients, blood samples were collected and examined for Plasmodium falciparum parasites using standard procedures. Patients’ biometric data were collected through Laboratory request forms and oral interviews. Results obtained showed an overall high prevalence of Plasmodium falciparum infection as 76.40% (243/318). Age group 0-9 years had the highest prevalence of 90.90% (20/22) while age group >50 years had the least prevalence of 60.00% (6/10). In terms of occupation, the prevalence was highest among students 82.20% (139/169) and lowest among staff/wards 67.20% (82/122). Males were more infected 80.90% (140/173) than females 71.00% (103/145). A high prevalence of 77.50% (79/102) was recorded in June, while August and July had prevalence rates of 76.50% and 75.00% respectively. The results showed significant differences (P < 0.05) in Plasmodium falciparum infection with respect to sex and occupation. However, the infection did not vary significantly (P > 0.05) across the age groups and months during which the study was conducted. The overall results revealed a high prevalence of Plasmodium falciparum infection in the study population which was perceived to have been aggravated by availability and proximity of mosquito breeding sites to inhabitants of the community, mosquito-man interactions, availability of human reservoir and the suitability of weather parameters in the study area. This study is expected to fill part of the knowledge gap on malaria entomology in Makurdi.

Keywords: Plasmodium falciparum, Malaria, University clinic, Makurdi, Nigeria.