February 2017

Modification of biochemical and haematological parameters during 90-days subchronic toxicity assessment of Carissa edulis in Wistar rats

A 90-days subchronic toxicity assay was evaluated on the aqueous extract of Carissa edulis leaves. Wistar rats were fed daily with oral doses of 125, 31.25 and 7.87 mg/kg of C. edulis leaves extracts. Toxic effects were assessed using physiological observation, body weight, relative organ weights, feed consumption, biochemical, haematological and histopathological parameters. Many changes of biological values were...

Author(s): Osseni Razack , Adanle Etienne, Adjagba Marius,  Bonaventure Awede,  Hountohotègbè Tatiana,  Bigot andré, Raphaël Darboux and Anatole Lalèyè