Journal of Veterinary Medicine and Animal Health
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Article Number - AEE8E7264297


Vol.9(6), pp. 110-115 , June 2017
DOI: 10.5897/JVMAH2017.0573
ISSN: 2141-2529



Full Length Research Paper

Observations of oxytetracycline treatment effects in a contagious bovine pleuropneumonia naturally infected herd in Zambia



Geoffrey Munkombwe Muuka*
  • Geoffrey Munkombwe Muuka*
  • Ministry of Fisheries and Livestock, Central Veterinary Research Institute, Lusaka, Zambia.
  • Google Scholar
Ana Songolo
  • Ana Songolo
  • Ministry of Fisheries and Livestock, Central Veterinary Research Institute, Lusaka, Zambia.
  • Google Scholar
Swithine Kabilika
  • Swithine Kabilika
  • Ministry of Fisheries and Livestock, Central Veterinary Research Institute, Lusaka, Zambia.
  • Google Scholar
Harvey Sikwese
  • Harvey Sikwese
  • Ministry of Fisheries and Livestock, Central Veterinary Research Institute, Lusaka, Zambia.
  • Google Scholar
Benson Bowa
  • Benson Bowa
  • Ministry of Fisheries and Livestock, Central Veterinary Research Institute, Lusaka, Zambia.
  • Google Scholar
Obrien Kabunda
  • Obrien Kabunda
  • Ministry of Fisheries and Livestock, Central Veterinary Research Institute, Lusaka, Zambia.
  • Google Scholar







 Received: 14 March 2017  Accepted: 24 April 2017  Published: 30 June 2017

Copyright © 2017 Author(s) retain the copyright of this article.
This article is published under the terms of the Creative Commons Attribution License 4.0


An observational study on the effects of oxytetracycline treatment on contagious bovine pleuropneumonia in a naturally infected herd of 500 cattle was conducted. A total of 68 cattle that showed pneumonia-like clinical signs were treated. Treatment was effected the moment an animal showed signs of illness. A total of 429 cattle were slaughtered after diagnosis of contagious bovine pleuropneumonia and at slaughter, 40.8% (175) had lesions compared to 59.2% (254) that did not have lesions. Out of the total cattle that were treated with oxytetracycline, 57.4% (39) died from contagious bovine pleuropneumonia over a period of 9 weeks while 42.6% (29) survived. Of the treatment group that survived, 37.9% (11) had fibrous lesions indicative of healing, while 62.1% (18) had pathological lesions consistent of active contagious bovine pleuropneumonia (CBPP). Categorisation of carcases with pathological lesions within the treatment group showed 66.7% (12) and 33.3% (6) of acute and chronic lesions, respectively. The CBPP causative agent was isolated through culture and confirmed using polymerase chain reaction (PCR). The results obtained suggest that oxytetracycline did not stop the spread or death of cattle in this particular herd with the treatment of a proportion of the herd. However, large scale field trials are needed in order to validate these findings. It is therefore recommended that any antibiotic that will be developed and advocated for use in the treatment of contagious bovine pleuropneumonia should be effective to contain spread within the herd by treating only a proportion showing signs of the disease.

Key words: Contagious bovine pleuropneumonia, antibiotics, lung, lesions, oxytetracyline, treatmen, Zambia.

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APA Muuka, G. M., Songolo, A., Kabilika, S., Sikwese, H., Bowa, B., & Kabunda, O. (2017). Observations of oxytetracycline treatment effects in a contagious bovine pleuropneumonia naturally infected herd in Zambia. Journal of Veterinary Medicine and Animal Health, 9(6), 110-115.
Chicago Geoffrey Munkombwe Muuka, Ana Songolo, Swithine Kabilika, Harvey Sikwese, Benson Bowa and Obrien Kabunda. "Observations of oxytetracycline treatment effects in a contagious bovine pleuropneumonia naturally infected herd in Zambia." Journal of Veterinary Medicine and Animal Health 9, no. 6 (2017): 110-115.
MLA Geoffrey Munkombwe Muuka, et al. "Observations of oxytetracycline treatment effects in a contagious bovine pleuropneumonia naturally infected herd in Zambia." Journal of Veterinary Medicine and Animal Health 9.6 (2017): 110-115.
   
DOI 10.5897/JVMAH2017.0573
URL http://academicjournals.org/journal/JVMAH/article-abstract/AEE8E7264297

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