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Article Number - 7CFB7F643200


Vol.5(1), pp. 1-5 , February 2014
DOI: 10.5897/MPR.2013.0105
ISSN: 2141-2596



Full Length Research Paper

Anal melanomas: The sun does not shine on this mucosa



Arcot Rekha
  • Arcot Rekha
  • Sri Ramachandra Medical College and Research Institute, Sri Ramachandra University, Chennai, India
  • Google Scholar
Leena Dennis Joseph
  • Leena Dennis Joseph
  • Sri Ramachandra Medical College and Research Institute, Sri Ramachandra University, Chennai, India
  • Google Scholar
Vishwanath M. Pai
  • Vishwanath M. Pai
  • Sri Ramachandra Medical College and Research Institute, Sri Ramachandra University, Chennai, India
  • Google Scholar







 Accepted: 21 August 2013  Published: 28 February 2014

Copyright © 2014 Author(s) retain the copyright of this article.
This article is published under the terms of the Creative Commons Attribution License 4.0


Cutaneous melanomas are rare in the Indian population and mucosal and anorectal lesions are seen but very occasionally. They often masquerade as hemorrhoids leading to delay in diagnosis. This was a retrospective study done in Sri Ramachandra University, where hospital records were perused to record all cases of anal melanomas. Abdomino-perineal resection and wide local excision offer equal survival rates. Novel targeted therapy represents the cutting edge of therapy today.
 
Key words: Anorectal, malignant melanoma, surgical treatment.
 

Ballo MT, Gershenwald JE, Zagars GK, Lee JE, Mansfield PF, Strom EA, Bedikian AY, Kim KB, Papadopoulos NE, Prieto VG, Ross MI (2002). Sphincter-sparing local excision and adjuvant radiation for anal-rectal melanoma. J. Clin Oncol. 20(23):4555-4558.
Crossref
 
Brady MS, Kaxolius JP, Quan SH (1995). Anorectal melanoma. A 64-year experience at Memorial Sloan-Kettering Cancer Center. Dis. Colon Rectum 38(2):146-151.
Pubmed
 
Bullard KM, Tuttle TM, Rothenberger DA, Madoff RD, Baxter NN, Finne CO, Spencer MP (2003). Surgical therapy for anorectal melanoma. J. Am. Coll. Surg. 196(2):206-211.
Crossref
 
Curtin JA, Fridlyand J, Kageshita T, Patel HN, Busam KJ, Kutzner H, Cho KH, Aiba S, Bröcker EB, LeBoit PE, Pinkel D, Bastian BC (2005). Distinct sets of genetic alterations in melanoma. N. Engl. J. Med. 353(20):2135-2147.
Pubmed 
 
McLaughlin CC, Wu XC, Jemal A, Martin HJ, Roche LM, Chen VW (2005). Incidence of non cutaneous melanomas in the US. Cancer 103(5):1000-1007.
Crossref
 
Ramakrishnan AS, Mahajan V, Kannan R (2008). Optimizing local control in anorectal melanoma. Indian J. Cancer 45(1):13-19.
Crossref
 
Sasaki S, Kojima T, Hidemura A, Hatanaka K, Uekusa T, Ishimaru M (2010). A case report of anorectal malignant melanoma showing a complete response after DTIC/ACNU/VCR therapy. Gan To Kagaku Ryoho 37(10):1999-2002.
Pubmed
 
Thibault C, Sagar P, Nivatvongs S, Ilstrup DM, Wolff BG (1997). Anorectal melanoma-an incurable disease. Dis. Colon Rectum 40(6):661-668.
Pubmed
 
Ueno H, Hase K, Mochizuki H (2001). Criteria for extramural perineural invasion as a prognostic factor in rectal cancer. Br. J. Surg. 88(7):994-1000.
Crossref
 
Wanebo H, Woodruff JM, Farr GH, Quan SH (1981). Anorectal melanoma. Cancer 47(7):1891-1900.
Crossref
 
Zhang S, Gao F, Wan D (2010). Abdomino perineal resection or local excision? A survival analysis of anorectal melanoma with surgical management. Melanoma Res. 20(4):338-341.
Pubmed

 


APA (2014). Anal melanomas: The sun does not shine on this mucosa. Medical Practice and Reviews, 5(1), 1-5.
Chicago Arcot Rekha, Leena Dennis Joseph and Vishwanath M. Pai. "Anal melanomas: The sun does not shine on this mucosa." Medical Practice and Reviews 5, no. 1 (2014): 1-5.
MLA Arcot Rekha, Leena Dennis Joseph and Vishwanath M. Pai. "Anal melanomas: The sun does not shine on this mucosa." Medical Practice and Reviews 5.1 (2014): 1-5.
   
DOI 10.5897/MPR.2013.0105
URL http://academicjournals.org/journal/MPR/article-abstract/7CFB7F643200

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