Medical Practice and Reviews

  • Abbreviation: Med. Pract. Rev.
  • Language: English
  • ISSN: 2141-2596
  • DOI: 10.5897/MPR
  • Start Year: 2010
  • Published Articles: 42

Full Length Research Paper

Bacterial wound infections in diabetic patients and their therapeutic implications

Ihsan Edan Abdulkareem Alsaimary
  • Ihsan Edan Abdulkareem Alsaimary
  • Department of Microbiology, College of Medicine, University of Basrah, P. O. Box 696, Ashar, Basrah, Iraq
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  • Article Number - E4C8E34474
  • Vol.1(2), pp. 12 - 15, June 2010
  •  Accepted: 24 February 2010
  •  Published: 30 June 2010

Abstract

In order to identify the bacterial pathogens associated with diabetic wounds and testing the antibiotic susceptibility of main antibiotics against predominant anaerobic bacterial types in comparison with some plant extracts, a total of 27 diabetic patients in each types; Insulin dependent (IDDM) and non-insulin dependent NIDDM and 30 non-diabetic patients with wound infection were introduced in the present study that was conducted between October - December 2007. It has been found that wounds are highly infected by aerobic and anaerobic bacterial types; Propionibacterium granulosum - as anaerobic bacteria- was a predominant pathogen in diabetic wound infections, in comparison withPseudomonas aeruginosa which is predominant in non-diabetic wounds. Amoxycillin/ calvulanic acid was the best effective antibiotic which gave 20 mm inhibition zone in comparison with other standard antibiotics, and aqueous extracts of Myrtus communis and Nerium oleander gave II and 10 mm inhibition zone, respectively.

 

Key words: Bacterial infections, diabetics, antibiotics