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Article Number - 569B7C314203


Vol.3(2), pp. 046-050 , February 2008

ISSN: 1992-2248



Full Length Research Paper

The role of ginger starch as a binder in acetaminophen tablets


Ibezim, E.C1., Ofoefule, S.I2., Omeje, E.O3*, Onyishi V.I2 and Odoh, U. E4.




 

1Department of Pharmaceutics, Faculty of Pharmaceutical Sciences University of Nigeria, Nsukka, Nigeria.

2Department of Pharmaceutical Technology and Industrial Pharmacy, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Nigeria.

3Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Nigeria.

4Department of Pharmacognosy, Faculty of Pharmaceutical Sciences University of Nigeria, Nsukka, Nigeria.


Email: winnomeje@yahoo.com






 Accepted: 10 January 2008  Published: 29 February 2008

Copyright © 2008 Author(s) retain the copyright of this article.
This article is published under the terms of the Creative Commons Attribution License 4.0


 

The rhizomes of ginger, Zingiber officinale (Roscoe; Zingiberacea) has been reported to contain up to 56.0% starch. The starch was extracted from the fresh rhizomes, evaluated for relevant properties and used as a binder to acetaminophen tablets at concentrations of 2.0 - 8.0% w/w. The tablets were evaluated for hardness, friability, weight uniformity, disintegration and dissolution profiles. Acetaminophen tablets containing gelatin as standard binder were produced and assessed comparatively. Results obtained indicate that ginger starch performed as good as gelatin as a binder to acetaminophen tablets.

 

Key words: Ginger, Zingiber officinale, binder, zingiberacea, acetaminophen.


APA (2008). The role of ginger starch as a binder in acetaminophen tablets. Scientific Research and Essays, 3(2), 046-050.
Chicago Ibezim, E.C., Ofoefule, S.I., Omeje, E.O, Onyishi V.I and Odoh, U. E.. "The role of ginger starch as a binder in acetaminophen tablets." Scientific Research and Essays 3, no. 2 (2008): 046-050.
MLA Ibezim, et al. "The role of ginger starch as a binder in acetaminophen tablets." Scientific Research and Essays 3.2 (2008): 046-050.
   
DOI
URL http://academicjournals.org/journal/SRE/article-abstract/569B7C314203

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