Scientific Research and Essays
Subscribe to SRE
Full Name*
Email Address*

Article Number - F70B56451271


Vol.10(5), pp. 177-183 , March 2015
https://doi.org/10.5897/SRE2013.5764
ISSN: 1992-2248


 Total Views: 0
 Downloaded: 0

Full Length Research Paper

Antimicrobial activity and phytochemical screening of crude water extract of the stem bark of Ficus glumosa.


H. A. Kwazo1, U. Z. Faruq2*, S. M. Dangoggo2, B. S. Malami3 and D. O. Moronkola




1Department of Chemistry Shehu Shagari College of Education Sokoto, Nigeria.

2Department of Pure and Applied Chemistry Usmanu Danfodiyo University Sokoto, Nigeria.

3Department of Animal Science, Usmanu Danfodiyo University Sokoto, Nigeria.

4Department of Chemical Sciences, Olabisi Onabanjo University, Nigeria.


Email: [email protected]






 Received: 03 December 2013  Accepted: 03 July 2014  Published: 15 March 2015

Copyright © 2015 Author(s) retain the copyright of this article.
This article is published under the terms of the Creative Commons Attribution License 4.0


Water and methanol extracts of the stem bark of Ficus glumosa were screened for their antimicrobial properties against Salmonella species. Preliminary results showed that the active compound was in the water extract. Therefore, the water extracts (hot and cold) were subjected to column chromatographic fractions and antibacterial screening. The most active fraction was subjected to phytochemical screening and finally Gas Chromatography Mass Spectrography (GC/MS) analysis. The result indicated that the most active fraction was the 3rd hot water extract and its GC/MS analysis was narrowed down to  3,3’-(4-methyl-1,3-phenylene)bis(1-heptylurea), isothujol and Terbuthyl azine. 
 
Key words: Phytochemical screening, Ficus glumosa, column chromatography and antimicrobial activity.
 

Ameh PO (2013). Physicochemical properties and rheological behaviour of Ficus glumosa gum in aqueous solution. Afr. J. Pure Appl. Chem. 7(1):35-43.
 
Doss AR (2008). Preliminary phytochemical screening and antibacterial studies of leaf extracts of Solanum trilobatum Linn. Ethnobotanical leaflets 6(12):42.
 
Gideon IO, Williams OT, Perpetua UN, Bright EI (2012). Antimicrobial and phytochemical evaluation of the leaf, stem bark and root extracts of Cyathulaprostrata (L) blume against some human pathogens. J. Intercult. Ethnopharmacol. 1(1):35-43.
Crossref
 
Faruq UZ, Hassan LG, Manga BS, Uba A, Olatunji MK, Tal MT, Isiak FS (2006). Anti-bacterial activity of Cassia occidentalis on Salmonella typhi. Proceedings of the 28th Annual International Conference Chemicals Society of Nigeria. pp. 177-181.
 
Hassan SW, Lawal M, Muhammad BY, Umar RA, Bilbis LS, Faruq UZ, Ebbo AA (2007). Antifungal activity and phytochemical analysis of column chromatographic fractions of stem bark extracts of Ficus sycomonus L. (Moraceae). J. Plant Sci. ISSN 1816-4951. Academic Journals Inc U SA.
 
Indranil B, Soroj KC, Soumendrananth C, Goutam C (2006). Antibacterial potentiality of Argemone maxicana solvent extracts against some pathogenic bacteria. Mem. Inst. Oswaldo Cruz 101(6) Riode Janeiro.
 
Jansen PCM (2005). Ficus glumosa Delile. In: Jansen PCM, Cardon, D (Eds.), PROTA 3: Dyes and tannins/Colorants et tanins. PROTA, Wageningen, Netherlands.
 
Kitzberger CSG, Smania A, Pedrosa RC, Ferreira SRS (2006). Antioxidant and antimicrobial activities of shiitake (Lentinula edoles) extracts obtained by organic solvents and supercritical fluids. J. Food Eng. 80:631-638.
Crossref
 
Nana F, Louis PS, Keumedjio F, Pantaléon A, Rizwana M, Victor K, Vincent R, Muhammad IC, Bonaventure TN (2012). Ceramides and cytotoxic constituents from Ficus glumosa Del. (Moraceae). J. Brazilian Chem. Soc. 23(3):482-487
Crossref
 
Oloyede OI (2005). Chemical profile of unripe pulp of Carica papaya, pak. J. Nurtr. 4:379-381.
 
Onuh MO, Ohazurike NC, Emeribe EO (2008). Efficacy of Jatropha curcus leaf extract in the control of brown blotch disease of cowpea (Vigna unguiculata). Biological Agriculture and Horticulture: An Int. J. Sustain. Prod. Syst. 25(3):201-207.
 
Opara AA, Ansa MA (1993). The antibacterial activity of tea and coffee on selected organism. J. Med. Lad. Sci. 3:45-48.
 
Olaokun OO, Lyndy JM, Jacobus NE, Vinny N (2013). Evaluation of the inhibition of carbohydrate hydrolysing enzymes, antioxidant activity and polyphenolic content of extracts of ten African Ficus species (Moraceae) used traditionally to treat diabetes. BMC Complementary and Alternative medicine, 13:94.
Crossref
 
Ouattara L, Koudou J, Zongo C, Barro N, Savadogo A, Bassole IHN, Ouattara AS, Alfred ST (2011). Antioxidant and Antibacterial Activities of Three Species of Lannea from Burkina Faso. J. Appl. Sci. 11:157-162.
Crossref
 
Suffnes M, Dowos J (1982). Current stating of the NCI plant and animal product programme. J. Natural Prod. 45:1-14.
Crossref
 
Sumitra CP, Jigna, Nehal K (2006). Evaluation of Antibacterial Activity and phytochemical Analysis of Bauhinia variegate L. bark. Afr. J. Biomed. Res. 9:53-56.
 
Tanko Y, Alladey O, Ahmed MK, Mohammed A, Musa KY (2012). The effect of methanol leaves extract of Ficus glumosa on gastrointestinal motility and on castor oil induced diarrhea in laboratory animals. J. Nat. Prod. Plant 2(3):360-367.
 
Trease C, Evan CW (1989). A text book of pharmacology. Thirteenth edition Brilliens, Tindall limited London.40-58:224-323.
 
Zayyanu UU (2010). The effect of ethanolic leaves extract of Ficus glumosa on blood glucose levels and some physiological parameters in diabetic rats (Unpoblished). A thesis submitted to the post graduate school, Ahmadu Bello University Zaria Nigeria.

 


APA Kwazo, H. A., Faruq, U. Z., Dangoggo, S. M., Malami, B. S., & Moronkola, D. O. (2015). Antimicrobial activity and phytochemical screening of crude water extract of the stem bark of Ficus glumosa.. Scientific Research and Essays, 10(5), 177-183.
Chicago H. A. Kwazo, U. Z. Faruq, S. M. Dangoggo, B. S. Malami and D. O. Moronkola. "Antimicrobial activity and phytochemical screening of crude water extract of the stem bark of Ficus glumosa.." Scientific Research and Essays 10, no. 5 (2015): 177-183.
MLA H. A. Kwazo, et al. "Antimicrobial activity and phytochemical screening of crude water extract of the stem bark of Ficus glumosa.." Scientific Research and Essays 10.5 (2015): 177-183.
   
DOI https://doi.org/10.5897/SRE2013.5764
URL http://academicjournals.org/journal/SRE/article-abstract/F70B56451271

Subscription Form