African Journal of
Biochemistry Research

  • Abbreviation: Afr. J. Biochem. Res.
  • Language: English
  • ISSN: 1996-0778
  • DOI: 10.5897/AJBR
  • Start Year: 2007
  • Published Articles: 384

AJBR Articles

July 2015

Diastatic enzymes malting process optimisation of African finger millet for biotechnological uses

This study sought to understand the importance of variation of steeping and germination conditions (temperature, pH and salts) on the quality of African finger millet malt in terms of diastic power (a-amylase and β-amylase), endo- (1,3) (1,4)-β-D-glucanase, b-glycan content and protein profile. The results show that the physiological responses of African finger millet malted seeds are correlated to pH (acidity...

Author(s): Adejoke N. Kolawole and Ayodele O. Kolawole

May 2015

Purification and biochemical properties of lipase from raphia palm fruit mesocarp

Lipases hydrolyze lipids to yield fatty acids and glycerol which are used as raw materials in industries. The lipase from raphia mesocarp was extracted, purified and characterized. Assay was carried out using p- nitrophenyl palmitate as substrate. The lipase was subjected to 80% ammonium sulphate precipitation, purified on ion exchange and gel filtration chromatography. Native and subunit molecular weights were...

Author(s): T.  Okunwaye, J.U. Obibuzor and E.A. Okogbenin

April 2015

Detection of DNA damage in lead (Pb) exposed city traffic wardens in Pakistan

Lead (Pb) is one of the toxic metals and is commonly used in industries. It affects multiple systems and has role in the production of reactive oxygen species (ROS). The objective of the present study was to determine Pb levels and to detect DNA damage in traffic wardens of Lahore, Pakistan. A total of 90 subjects were selected including 60 traffic wardens working in field and 30 working in administrative zones. The...

Author(s): Ayesha Pervez, Fozan Ahmed, Nazish Mehmood Aisha, Salman Idrees, Muhammad Ikram Ullah, Mohammad Zamir Ahmad, Aftab Ahmed and Muhammad Jawad Hassan

April 2015

Biochemical changes in blood and tissues of Wistar rats following administration of anti-tuberculosis drugs

Tuberculosis (TB) remains a major public health problem worldwide especially in resource-limited countries of Africa and Asia. The disease is curable with drugs but information on biochemical changes and oxidative indices due to anti-TB drugs is not readily available. This study was designed to investigate in vivo effects of anti-TB drugs in male Wistar rats. Fourteen adult male rats were randomly divided into two...

Author(s): Aderemi Oludiran Kehinde, and Oluwatosin Adaramoye

March 2015

Effect of some traditional edible oils on sex hormones of albino Wistar rats

The effect of some traditionally extracted edible seed oils (sesame, peanut and melon oils) on some sex hormones - prolactin, progesterone, testosterone, estradiol, luteinizing hormone (LH) and follicle stimulating hormone (FSH) of albino Wistar rats was studied. Sixty (30 - 50 g) weanling rats (20 males and 40 females) were purchased and housed separately until they weighed 120 to 150 g. Afterwards, the rats were...

Author(s): Margaret Akpana Agiang, Olajumoke Josephine Matthew, Item Justin Atangwho and Patrick Ekong Ebong

March 2015

Plasma lipid profile including the high density lipoprotein (HDL) subclasses in hypertensive patients in Ouagadougou, Burkina Faso

The study was undertaken to evaluate the interest of cholesterol subclasses in the management of hypertensive patients recruited at University Hospital Yalgado Ouedraogo of Ouagadougou (Burkina Faso, West Africa). The distribution of hypertensive was reported as 45 (35.4%) without complications, 42 (33%) with cardiovascular complications and 40 (31.4%) with diabetes. Any difference in lipids profile was observed when...

Author(s): Alice T. C. R. Kiba Koumaré, Absetou Guira, André Samandoulougou, Elie Kabré, Issaka Sondé, Talkmore Maruta, Jacques Simporé and Jean Sakandé

March 2015

Diabetes and pre-diabetes in adult Nigerians: Prevalence, and correlations of blood glucose concentrations with measures of obesity

The quantification of the number of people with diabetes is an important factor that allows for effective planning and distribution of scarce resources for the management of diabetes. This study therefore investigated the prevalence of diabetes and impaired fasting glucose in a convenient population of adults in Umudike, a semi-urban town in South-East Nigeria. The relationship between measures of obesity and blood...

Author(s): Chukwunonso E. C. C.  Ejike, Nnamdi K. Uka and Stella O. Nwachukwu

February 2015

Glycated proteins: Clinical utility and analytical approaches

The binding of glucose to serum proteins in a non-enzymatic reaction occurs proportionately to the prevailing serum glucose concentration during the lifespan of each protein. The non-enzymatic reaction of proteins with reducing sugars results in the formation of glycated proteins that are indicative of the relative amount of reducing sugars present. Hemoglobin, albumin, lipoproteins and other tissue proteins can be...

Author(s): Yoseph Cherinet Megerssa and Demo Yemane Tesfaye

February 2015

Characterization of partially purified cysteine protease inhibitor from Tetracarpidium conophorum (African walnut)

Cysteine protease inhibitors (CPIs) have been known to be present in a variety of seeds of plants, and have been intensively studied as useful tools for potential utilization in pharmacology. This study reports the isolation of CPI from Tetracarpidium conophorum by 65% ammonium sulphate saturation, followed by ion exchange chromatography; further purification was by gel filtration chromatography. The molecular weight of...

Author(s): Obayomi, A., Adeola, S. A., Bankole, H. A. and Raimi, O. G.,

February 2015

Effects of sound waves on the enzyme activity of rice-koji

Rice-koji is an important agent for the saccharification of fermented food production in Japan. In koji-making, temperature, humidity, light and oxygen are important environmental factors. However, there is no report of koji-making controlled by sound wave. In this study, focusing on the enzyme activity of rice-koji, we confirmed the relationship between enzyme activity and frequency of sound waves. Here, the enzyme...

Author(s): Noriaki Saigusa, Seika Imayama and Yuji Teramoto

January 2015

Changes in enzymes activities of soil samples exposed to electromagnetic radiations (EMR) from mobile phone

This study aimed at investigating the changes in activities of dehydrogenase, catalase, alkaline phosphatase, acid phosphatase and alkaline protease of soil samples exposed to electromagnetic radiations (EMR) from mobile phone for the periods of 0, 30, 60 and 90 days. EMR-unexposed soil samples served as the source of control enzyme activities. The mean enzyme activities from the EMR-exposed soil were significantly...

Author(s): C. I. Iheme, R. N. Nwaoguikpe, S. E. Abanobi, C. U. Igwe, E. C. Udenze, A. U. Ezirim, C. P. Ihedimbu and D. I. Ukairo

January 2015

Higher tolerance of a novel lipase from Aspergillus flavus to the presence of free fatty acids at lipid/water interface

The main objective of this work was to identify novel lipases of industrial interest. In this paper, Aspergillus flavus lipase (AFL) was isolated from the traditional tannery of Fez city in Morocco; it kept its stability even in the presence of high concentrations of detergent from 0 to 10 mM sodium deoxycholate (NaDC). Bile salts showed no inhibitory effect on the lipolytic activity, whereas the calcium salts showed a...

Author(s): Faouzi Laachari, Fatimazahr​a El Bergadi, Moulay Sadiki, Adel Sayari, Wifak Bahafid, Soumya Elabed, Iraqui Mohammed and Saad Koraichi Ibnsouda

November 2014

A study of two weeks administration of copper sulphate on markers of renal function and feeding pattern of Wistar rats

This study aimed at determining the changes in food consumption, water intake, plasma and urine concentrations of some organic constituents which are often used in the assessment of renal function following two weeks’ administration of two doses of copper sulphate to Wistar rats. Fifteen adult male Wistar rats were randomly divided into three groups of five rats each. Group I (control group) received distilled...

Author(s): Rufus O. Akomolafe, Olaoluwa S. Olukiran, Chris E. Imafidon, Olugbengba A. Ayannuga, John A. Oyekunle, Babatunde O. Akanji and Ayowole A. Oladele

November 2014

Radiation protection and anti-oxidative effects of garlic, onion and ginger extracts, x-ray exposed albino rats as model for biochemical studies

The present study investigates and examines the comparative effects of plant extracts such as, garlic, ginger and onion on some organs (liver, kidney and heart) of x-ray exposed rats, using and assaying some biochemical enzymes. Twenty (20) albino rats with an average weight of (155.00 ± 2.01 g), divided into five groups were used for the study. The rats with exception of the control were exposed to x-ray with...

Author(s): Kenneth C. Nwachukwu, Samuel O. Asagba, Chibueze Nwose and Michael P. Okoh

October 2014

Effect of rosemary (Rosmarinus officinalis) on lipid profiles and blood glucose in human diabetic patients (type-2)

Investigation of the effect of oral administration of rosemary (Rosmarinus officinalis) as powder on lipid profiles and blood glucose in healthy and type-2 diabetic human patients was done. Forty-five type-2 diabetic patients and 15 non-diabetic persons of age 40 years or older participated in the study. Patients selected in this study had fasting blood glucose in the range 160-300 mg/dl, and high lipid profiles levels....

Author(s): Abdulrahim Al Jamal

October 2014

Hypolipidemic effect of Irvingia gabonensis fruits juice on sodium fluoride induced dyslipidemia in rats

Effect of Irvingia gabonensis fruit juice administration on serum lipid profile of sodium fluoride (NaF)-intoxicated rats was investigated. Twenty-four (24) male Wistar rats divided into four groups of six (6) animals each - one control and three intoxicated groups were used. The normal control (NC) group received only standard pelletized diet and water. All three intoxicated groups received 20 mgkg-1 bodyweight of NaF...

Author(s): Emejulu, Adamma Angela, Alisi, Chinwe Sylvanus, Asiwe, Emeka Sabastine, Iheanacho, Kizito Munachiso and Onwuliri, Viola Adaku

September 2014

Replacement of bakery shortening with rice bran oil in the preparation of muffins

Studies were carried out to replace bakery shortening with refined rice bran oil in the preparation of muffins. Physico-chemical properties of bakery shortening and rice bran oil were studied. Rice bran oil was found to have a higher content of the essential fatty acid linoleic acid (34.98%) as compared to that of bakery shortening (5.14%). Chemical composition of wheat flour used was also studied. Muffin samples were...

Author(s): Kaur, A, Vishaldeep Jassal and Bhise, S. R.

September 2014

Safety evaluation for multispecies probiotics in a 28-day feeding study in Sprague-Dawley rats

This experiment evaluated the 28-day feeding study in rats after they were continuously fed with multi-species probiotics dosages in the low-dosage, medium-dosage, and high-dosage groups: 2,000 mg/kg body weight (B.W.), 4,000 mg/kg B.W., and 6,000 mg/kg B.W., respectively, for 28 days as a reference for the safety of its repeated usage. Each group consisted of 10 male and 10 female Sprague-Dawley (SD) rats and the test...

Author(s): Chun-Chih Huang, Mun-Kit Nam, Yueh-Ting Tsai and Cheng-Chih Tsai

September 2014

Lead and cadmium residue determination in spices available in Tripoli City markets (Libya)

In recent years, there has been a growing interest in monitoring heavy metal contamination in food products. Spices can improve the taste of food and can also be a source of many bioactive compounds but can unfortunately, also be contaminated with dangerous materials, potentially heavy metals. This study was conducted to investigate lead (Pb) and cadmium (Cd) contamination in selected spices commonly consumed in Libya...

Author(s): Mohamed Ziyaina, Ahlam Rajab, Khadija Alkhweldi, Wafia Algami, Omer Al-Toumi and Barbara Rasco

August 2014

Plasmodium berghei ANKA: Selection of pyronaridine resistance in mouse model

Pyronaridine is a partner drug in, Pyramax®, a combination of artesunate (ASN)-pyronaridine (PRD) which was recently prequalified by WHO drug as a potential alternative for treatment of malaria in African setting. Pyronaridine is a mannich base, with a long half-life, thus predisposed to resistance. In this study, we selected pyronaridine resistance by submitting Plasmodium berghei ANKA line in vivo to increasing...

Author(s): Kimani S. K., Ng’ang’a J. K., Kariuki D. W., Kinyua J., Kimani F. T. and Kiboi D. M.,

August 2014

Influence of CaCl2 and EDTA on reversible thermal inactivation of recombinant wild-type and mutant (E40H/E44H) Phlebia radiata manganese peroxidase 3 (rPr-MnP3)

Thermal inactivation of a new recombinant Phlebia radiata manganese peroxidase (rPr-MnP3) in the presence and absence of additives (CaCl2 and EDTA) is described for the first time. The influence of temperature and melting points (Tm) on the stability of rPr-MnP3 and its mutant (E40H/E44H) were determined. There was no significant inactivation at 25 – 40°C. However, we observed rapid inactivation of rPr-MnP3 at...

Author(s): Usenobong F. Ufot and Monday I. Akpanabiatu

May 2014

Effects of dietary tyrosine on serum cholesterol fractions in rats

The present study was undertaken to measure the effects of dietary tyrosine added to rat diet on serum cholesterol levels in the rat. A total of twenty Wistar strain albino rats were fed with different doses of tyrosine enriched diets containing 0.8 g/100 g, 1.0 g/100 g and 1.2 g/100 g. After 3 weeks of experimental feeding, there was significant increase (p<0.05) in total postprandial serum cholesterol of rats fed...

Author(s): ANADUAKA, Emeka Godwin, EGBA, Simeon Ikechukwu, UGWU, Jecintha Uchenna, APEH, Victor Onukwube and UGWU Okechukwu Paul-Chima

May 2014

Antidenaturation and antioxidative properties of phytochemical components from Spondias mombin

The antidenaturation and antioxidant properties of Spondias mombin Linn (Anacardiaceae) methanol leaf extract (SMC) and fractions prepared from it were evaluated in this study. SMC and its fractions: ether (SME), saponin-rich (SMS) and flavonoid-rich (SMF) were phytochemically screened and evaluated for total antioxidant activity (TAA), ability to inhibit deoxyribose degradation (DEO), lipid peroxidation inhibitory...

Author(s): Afolabi C. Akinmoladun, Olamide O. Crown, Olubukola B. Ojo, Tolulope M. Olaleye and Ebenezer O. Farombi

April 2014

Aqueous Bridelia ferruginea stem bark transaminase activities in albino rats

The major objective of this study was to evaluate the transaminase activities of albino rats fed with aqueous extract of Bridelia ferruginea stem bark. Sixteen (16) albino rats with weight ranging between 100-190 g were used. The rats were divided into four groups; with group four as the control group. Increasing doses (100, 200 and 400 mg kg-1 body weight) of the extract were administered orally to the other three...

Author(s): Olarewaju O. I., Oloyede O. I., Ojo O. A, Onikanni S. A and Ajiboye B. O

April 2014

Properties of arginase from gut of adult cockroach (Periplaneta americana)

Arginase (EC catalyzes the hydrolysis of arginine to ornithine and urea. The role of arginase in insect has been seen in the growth of insect at various stages of development and energy requirement for flight. Here, we reported the properties of arginase in the gut of adult cockroach, Periplaneta americana. The enzyme was partially purified with ammonium sulphate precipitation and affinity chromatography. The...

Author(s): Okonji R. E., Ehigie L. O. and Soyelu O. J.

March 2014

Usefulness of liver and kidney function parameters as biomarkers of ‘heavy metals’ exposure in a mammalian model Mus musculus

The toxicological evaluations of cadmium (Cd), iron (Fe), manganese (Mn), lead (Pb) and zinc (Zn) were carried out against Albino mice model, Mus musculus. On the basis of LC50 value, Cd (0.47 mM) was found to be the most toxic followed by Zn (2.40 mM), Pb (2.42 mM), Fe (4.52 mM) and Mn (5.70 mM) as least toxic. The results of the sublethal concentration of the heavy metals (1/10th of 96 hrLC50) on the liver function...

Author(s): Osuala Fidelia I., Otitoloju A. A. and Igwo-Ezikpe M. N.

March 2014

Properties of rhodanese from the liver of tilapia, Oreochromis niloticus, in Asejire Lake, Nigeria

The study investigates the purification and characterisation of rhodanese from the liver of the tilapia fish (Oreochromis niloticus) collected from Asejire Lake in Nigeria. This was with a view to understanding the biochemical basis of the survival of the fish in cyanide polluted water. Rhodanese was isolated and purified from liver tissue homogenate of tilapia using CM-Sephadex ion exchange chromatography and Sephadex...

Author(s): Atere Tope Gafar, Ademakinwa Adedeji Nelson and Agboola Femi Kayode

February 2014

Serum lipids and oxidized low density lipoprotein levels in sickle cell disease: Assessment and pathobiological significance

One hundred and eighteen (118) subjects aged 15 to 36 years divided into control subjects (AA n = 42), heterozygous sickle cell patients (AS n = 33) and homozygous sickle cell patients (SS n = 43) were investigated for a lipid profile including the measurement of oxidized low density lipoprotein (LDL) to assess the risk of early atherosclerosis in sickle cell disease. The results show that total, high density...

Author(s): Diatta Alassane, Cissé Fatou, Guèye Tall Fatou, Diallo Fatou, Touré Fall Awa Oumar, Sarr Gaston Ndéné, Lopez Sall Philomène, Sall Niama Diop and Touré Méïssa

February 2014

Treatment of lead-poisoned rats through oral administration of palm oil extracts

The palm fruit (Elaies guineensis) is the source of palmitic-oleic rich semi-solid fat and fat-soluble minor components, made up of vitamin E (tocopherols and tocotrienols), carotenoids and phytosterols. This study was in two parts. Firstly, it examined the effects of palm oil fractionation methods on recovery and concentration of carotenes, tocopherols and tocotrienols which are known to have nutritional and medicinal...

Author(s): Peter Twumasi, Kwabena Nsiah and Emmanuel Yeboah Osei

February 2014

Extraction and comparison of fibrolytic enzyme additives from gut of 11 ungulates

Microbial populations in herbivores gut attack, degrade and ferment structural carbohydrates in forage cell walls, producing volatile fatty acids and microbial proteins for the host. Exocellulases, endocellulases and cellobiases are the major cellulolytic enzymes while hemicellulase (xylanase) exposes cellulose for fermentation. This study aimed to isolate proteins that hydrolyse fibre or assist fibrolysis in any way...

Author(s): Fabian Nde Fon, Ignatius Verla Nsahlai and Peter Frank Scogings

February 2014

Effects of n-butanol fraction of Gongronema latifolium leave extract on some biochemical parameters in CCl4- induced oxidative damage in Wistar albino rats

Effects of n-butanol fraction of Gongronema latifolium leave extract on some biochemical parameters in carbon tetrachloride-induced oxidative damage in Wistar albino rats were assessed. Fifty-four (54) Wister albino rats were divided into treatment group and LD50 groups. Group A (normal control) was given feed and water, Group B (vehicle control) was injected with olive oil intraperitoneally, while the rest groups (C,...

Author(s): Okpala, J. C., Sani, I., Abdullahi, R., Ifedilichukwu, H. N. and Igwe, J. C.

January 2014

Proximate composition of Rastrineobola argentea (Dagaa) of Lake Victoria-Kenya

Proximate composition analysis for crude lipid content, crude protein content, moisture content, total ash content and dry weight of Dagaa (Rastrineobola argentea): a small pelagic fish which constitutes one of the main fish species in Lake Victoria was determined from selected beaches: Paga, Dunga, Rota, Usari and Nduru around Lake Victoria-Kenya. This was done with a view to provide nutritional data to guide food...

Author(s): Ogonda, Lydia Awuor, Muge, Edward Kirwa, Mulaa, Francis Jackim and Mbatia, Betty Nyambura

January 2014

The protective role of oral consumption of N-acetyl cysteine during a single session of exhaustive exercise in untrained subjects

The aim of the current study was to verify the effect of N-acetyl cysteine (NAC) supplementation on markers of oxidative stress and inflammatory response during a single session of exhaustive exercise. In a randomized placebo-controlled double-blind clinical trial, thirty healthy, untrained young males and females with a mean age of 21.33±2.39 years, weight of 59.63± 9.24 kg and height of...

Author(s): Iranpour D, Movahed ALI, Goudarzi A, Tarverdizadeh Bahman, Akbarzadeh Samad, Motamed Niloufar, Pakdel Farhad, Hagian Ali Akbar, Seyedian Ramin, Vahdi Saeid and Tahmasebi Rahim

January 2014

A microassay for quantification of 2,2-diphenyl-1-picrylhydracyl (DPPH) free radical scavenging

Polyphenols are the second largest abundant organic molecules in nature. One of the principal reported biological activities is the antioxidant capacity. 2,2-Diphenyl-1-picrylhydracyl (DPPH) method has been used to quantify polyphenols antioxidant activity in many different products with reproducible and reliable results. We proposed and validated a methodology to analyze this antioxidant activity with smaller amount of...

Author(s): Norma P. Meléndez , Virginia Nevárez-Moorillón, Raúl Rodríguez-Herrera, José C. Espinoza and Cristóbal N. Aguilar

January 2014

The composition of fatty acids stored in liver, muscle and fat tissues of the African lungfish Protopterus annectens (Owen, 1839)

The composition and profile (%) of fatty acids stored in liver, muscle, and fat tissues of the fresh-water African lungfish Protopterus annectens were determined by gas chromatography. High content of total fatty acids (TFA) was found in fat (62.06 ± 3.4 g/100 g) followed by liver (50.68 ± 4.72 g/100 g) and muscle tissues (10.9 ± 0.81 g/100 g). Saturated fatty acids (SFA) formed 72.9% TFA in the...

Author(s): H. A. Elagba Mohamed and Jamal N. Al-Sabahi

January 2014

Collaborative effects of some anti-diabetic plants on the liver marker enzymes of diabetic rats

The leaves of Psidium guajava, Anacardium occidentale, Eucalyptus globulus and fruits of Xylopia aethiopica are used in the management of diabetes mellitus. The phytochemical constituents as well as the acute toxicity of the combined chloroform extracts (A. occidentale + E. globulus and P. guajava + X. aethiopica) and their effects (at graded doses of 100 and 250 mg/kg body weight each) on the activities of alanine...

Author(s): GOMETI Ajiroghene S., OGUGUA Victor N., ODO Christian E., JOSHUA Parker E. and OBI Kelechi N.

December 2013

Effects of fungal (Lachnocladium spp.) pretreatment on nutrient and antinutrient composition of corn cobs

The nutritive value of corn cob following pretreatment by fermentation with fungal species of Lachnocladium spp. was investigated. Corn cob was milled and subjected to incubation with fungal species for a period of one week. Significant increase (p<0.05) in protein, ash and some mineral elements were observed. Calcium, magnesium, zinc and sodium content were observed to be higher in fermented cobs while significant...

Author(s): A. Olagunju, E. Onyike, A. Muhammad, S. Aliyu and A. S. Abdullahi

December 2013

Ferric reducing antioxidant power and total phenols in Cordia africana fruit

Antioxidants are beneficial compounds found in a lot of foods. Cordia africana (Lam.) is a small fruit eaten all over Tigray and other parts of Ethiopia. The fruit was tested for its antioxidant content using the ferric reducing antioxidant power (FRAP) assay and total phenols (TP) measured with Folin Ciocalteu`s reagent, across four different agroecological zones and three land use classes in Tigray. The average FRAP...

Author(s): Tewolde-Berhan Sarah, Remberg Siv Fagertun, Abegaz Kebede, Narvhus Judith, Abay Fetien and Wicklund Trude

December 2013

Impact of Anthocleista vogelii root bark ethanolic extract on weight reduction in high carbohydrate diet induced obesity in male wistar rats

Obesity increases the risk of developing a number of diseases such as insulin resistance, type 2 diabetes, hypertension, hypercholesterolemia, stroke and heart attack. The aim of this study was to investigate the impact of ethanolic root bark extract of Anthocleista vogelii on weight reduction in high carbohydrate diet (HCD) induced obesity in male Wistar rats. Thirty male Wistar rats were housed in three...

Author(s): Anyanwu, G. O., Onyeneke, E. C., Usunobun, U. and Adegbegi, A. J.

November 2013

Marine fungal metabolites as a rich source of bioactive compounds

This paper reviews the recent results of bioactive compounds derived from marine fungi, which are highly diversified and are less explored. Researchers are showing keen interest in isolating novel bioactive compounds with clinical applications. Hence, here we discussed most of the bioactive compounds isolated from marine derived fungi and their possible roles in various efficient biological activities. Key words:...

Author(s): J. Swathi, K. Narendra, K. M. Sowjanya and A. Krishna Satya

November 2013

Production of tannase and gallic acid by Aspergillus tamarii in submerged and solid state cultures

The hydrolytic enzyme, tannase and the antioxidant phenolic compound, gallic acid are useful in many biotechnological processes especially in food and pharmaceutical areas. The purpose of this study was to evaluate the production of tannase and gallic acid by Aspergillus tamarii developed in submerged and solid state cultures using tannic acid as substrate. In submerged cultures, maximal tannase activity (20,400...

Author(s): Andrea Miura da Costa, Cristina Giatti Marques de Souza, Adelar Bracht, Marina Kimiko Kadowaki, Aline Cristine da Silva de Souza, Roselene Ferreira Oliveira and Rosane Marina Peralta

November 2013

Physicochemical parameters and selected heavy metals assessment of drinking water at the students’ residences of the Nigerian Premier University

Heavy metals contamination of drinking water is an important health risk factor due to the attendant toxic effect linked to it. We therefore assessed the quality of borehole, tap and well water samples in each of the seven students’ residential areas of University of Ibadan. Physicochemical parameters of the water samples including pH, turbidity, total suspended solids (TSS), total dissolved solids (TDS), as well...

Author(s): O.A Odunola, M. A. Gbadegesin, S.E. Owumi, K.A. Akinwumi and B. Ogunbiyi

October 2013

Effect of combined use of Ocimum gratissimum and Vernonia amygdalina extract on the activity of angiotensin converting enzyme, hypolipidemic and antioxidant parameters in streptozotocin-induced diabetic rats

  This study was aimed at investigating the angiotensin converting enzyme (ACE) inhibitory effect, hypolidemic and antioxidant properties of combined extract of Occimum gratissimum andVernonia amygdalina in streptozotocin-induced diabetic rats. Thirty (30) apparently healthy male Wistar rats were grouped into: control, diabetic, diabetic + insulin, diabetic + 100 mg/kg and diabetic + 250 mg/kg...

Author(s): Abdulazeez Mansurah A., Ibrahim Kassim, Bulus Kenpia, Babvoshia Hope B. and Abdullahi, Yusuf

  • Article Number: 48ABB2511691

October 2013

Effect of oestrous cycle on serum electrolytes and liver enzymes in Red Sokoto goats

  This study was carried out to determine changes in serum electrolytes and liver enzymes during the oestrous cycle in Red Sokoto goats. Eleven (11) apparently healthy Red Sokoto goats were synchronized with a single injection of 7.5 mg of PGF2α. The goats were bled via jugular venipuncture in oestrus or late oestrus, metoestrus/early dioestrus, mid-dioestrus and late dioestrus/proestrus. Mean serum...

Author(s): Yaqub, L. S., Kawu, M. U., Ayo, J. O., Ambali, S. F., Habibu, B.

  • Article Number: C13FD4311695

October 2013

The effects of Yucca schidigera on blood glucose and lipid levels in diabetic rats

  The aim of this study was to investigate the effects of Yucca schidigera (YSE) on lipid peroxidation and some biochemical parameters in streptozotocin-induced (STZ) diabetic rats. Four groups of seven rats each were used in this study. Supplementation period was three weeks. The groups were: I. control group (C), normal feed; II. diabetic (DM-YSE), normal feed plus YSE 100 ppm/kg; III. diabetic...

Author(s):   Nuray OZTASAN

  • Article Number: 1C4D19C11705

September 2013

Phosphotidylcholine as a new strategy in biocompatible material

  Biomaterial has a wide variety of usages in medicine and chemistry. The biomaterials used in medicine and chemistry are often polymers. Polymers used as biomaterial must be compatible to the environment and they must not be poisonous and in case they are broken down they must not provide poisonous products in biological environment. The biomaterial used for each case has certain and specific chemical and...

Author(s): Reihaneh Sabbaghzadeh

  • Article Number: 779057A11651

September 2013

Optimization of metalloprotease production by Eupenicillium javanicum in both solid state and submerged bioprocesses

  Proteases are enzymes that have great importance in industries and can be produced through bioprocess by microorganisms. Changes in parameters can influence the production rate of these enzymes. The current study evaluated the influence of these parameters on the production of proteases by the fungus Eupenicillium javanicum under both solid state bioprocess (SSB) and submerged bioprocess (SmB), and...

Author(s): Youssef Ali Abou Hamin Neto, Cristina Maria de Souza Motta and Hamilton Cabral

  • Article Number: 0C1528E11671

September 2013

The changes of fatty acid composition in sun dried, oven dried and frozen hake (Merluccius merluccius) and sardinella (Sardinella aurita)

  The fatty acid composition and fat quality alteration of the round sardinella (Sardinella aurita) and the European hake (Merluccius merluccius) fillets during the frozen storage (-30°C), sun drying and controlled oven drying (temperature = 60°C, air velocity = 2 m/s and relative humidity = 20%) were investigated. Results show that the fresh fillets of the S. aurita and M....

Author(s): Khaoula Telahigue, Tarek Hajji, Imen Rabeh and M’hamed El Cafsi.

  • Article Number: 4EF736A11679

September 2013

An evaluation of antioxidants and oxidative stress in Iraqi patients with thyroid gland dysfunction

The present study evaluates the effects of hypothyroidism and hyperthyroidism states on antioxidant vitamins (A, E, C, β-carotene) and uric acid in Iraqi patients before treatment. Lipid peroxidation, an index of oxidative stress was elevated in hyperthyroidism but reduced in hypothyroidism patients as compared to control. The results showed a highly significant decrease in the sera levels of Vitamins A, E...

Author(s): Salwa H. N. Al-Rubae&#;i and Abass K. Al-Musawi

  • Article Number: F52ABDD12516

August 2013

Tea Artemisia annua inhibits Plasmodium falciparum isolates collected in Pikine, Senegal

  Malaria is a major scourge of most countries in Africa which continues to defy science and technology. Several medicinal plants are traditionally used for the treatment of malaria and other protozoa infections. We aimed to assess by the Double-site Enzyme-linked Lactate dehydrogenase enzyme Immuno-detection (DELI) test for the first time in Senegal, Plasmodium falciparum isolates in...

Author(s): Gueye Papa El hadji Omar, Diallo Mouhamadou, Deme Awa Bineta, Badiane Aida Sadikh, Dior Diop Mare, Ahouidi Ambroise, Abdoul Aziz Ndiaye, Dieng Thérése, Lutgen Pierre, Mboup Souleymane and Sarr Ousmane

  • Article Number: 4CE4F3411597

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