Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3834

JMPR Articles

Indigenous knowledge of plant uses by the community of Batiaghata, Khulna, Bangladesh

June 2021

Southwestern region of Bangladesh is very rich in floral diversity, and their diversified uses. An extensive survey was conducted to investigate ethnobotanical applications of botanical species by the community of Khulna, Bangladesh. We focused on plants and community relationships, identify the most important species used, determine the relative importance of the species surveyed and calculated the Fidelity level (FI)...

Author(s): Tama Ray, Sharif Hasan Limon, Sajjad Hossain Tuhin and Arifa Sharmin  

Polyphenols quantification and antioxidant activity of methanolic and aqueous extracts from eight medicinal plants used to manage avian diseases in Burkina Faso

May 2021

The present study aimed to quantify the polyphenols and evaluate the antioxidant activity of methanolic and aqueous extracts from eight medicinal plants used by the poultry farmers to manage avian diseases in Burkina Faso. Total phenolics and total flavonoids were quantified using Folin-Ciocalteu and AlCl3 reagents, respectively. The antioxidant activity was evaluated using three methods:...

Author(s): Windmi Kagambega, Roland Nâg-Tiéro Meda,Benjamin Kouliga Koama ,, Anne-Flora Drabo, Hadidjatou Belem, Der Dabire, Jacques Kabore, Amadou Traore and  George Anicet Ouédraogo  

In vivo study of antiplasmodium and histological activity of Garcinia kola and Aloe vera extracts against falciparum malaria

May 2021

This study focuses on testing the efficacy of herbal remedy used in many homes within the South-Eastern part of Nigeria to treat malaria and also the histopathological effect of the remedy on albino rats. Twenty rats were procured and distributed with five rats to one group. Group 1 received Garcinia kola and Aloe vera extracts, Group 2 received only G. kola extract, Group 3 is negative control and Group 4 is positive...

Author(s): Onyinyechi Cecilia Amobi-Alor, Adanna Cynthia Eze, Chineye Lucy Ugwute, Nneka Mariam Unachukwu, Chika Udeh, Simeon Okolo, Chidimma Claribel Chikezie, Kelechi Mbah-Omeje and Felix Chukwuebuka Onyia  

Bioactive profile of mandacaru fruits and cytotoxicity against the L929 cell line

May 2021

Mandacaru (Cereus jamacaru DC. Subsp. Jamacaru) is native to the Brazilian Caatinga and is part of the Cactaceae family. Mandacaru fruits are attractive in taste and flavour, although they are not widely commercialised. However, there is limited scientific literature on the composition of this fruit. Therefore, the present work was aimed at analysing the physicochemical composition, as well as in vitro antioxidant...

Author(s): Jamiles Francisca dos Santos, Jenisson Linike Costa Gonçalves, Raphael Amancio de Jesus, Paulo Cesar de Lima Nogueira, Ricardo Scher, Antonio Martins de Oliveira Júnior and Jane de Jesus da Silveira Moreira,  

Berberis vulgaris aqueous extract prevention of carbon tetrachloride induced hepatotoxicity and lipopolysaccharides/paracetamol induced hepatitis in rats

May 2021

The aim of this study was to evaluate the effect of Berberis vulgaris water extract (BWE) against CCl4-induced hepatotoxicity and LPS/PCM induced- hepatic inflammation in the experimental animal models. CCl4 (100 ug/kg, oral) administration for 28 days as well as the co-administration of LPS (250 ug/kg bw) and PCM (2 g/kg bw) for 28 days resulted in massive elevation in serum and hepatic prooxidants and inflammatory...

Author(s): Mohamed Ahmed Moustafa, Doaa Ahmed Ghareeb, Maha A. El-Demellawy, and Mohamed Mahmoud Elsayed  

New naphthalene derivative isolated from Diaporthe sp. host to Syzygium cordatum Hochst.ex Krauss plant

May 2021

Fungal endophytes are regarded as inexhaustible sources of pharmaceuticals and agrochemicals with profound antibacterial, anticancer or antifungal activities. Diaporthe sp., an endophytic fungus residing in medicinal plant S. cordatum, showed a good antagonism against bacterial pathogens of beans; Pseudomonas syringae pv phaseolicola (Psp) and Xanthomonas axonopodis pv phaseoli (Xap), with zones of inhibitions of 14.00...

Author(s): Towett Kipngetich Erick, Joyce Jepkorir Kiplimo and Josphat Matasyoh  

Antiurolithiatic activity of selected plants extracts against calcium oxalate crystals

April 2021

The present study was designed to evaluate the antiurolithiatic activity of selected plants extracts (Achyranthes aspera, Lawsonia inermis, Ficus benghalensis, Raphnus sativus and Macrotyloma uniflorum). The methanol extract of selected plants was analysed for in-vitro antiurolithiatic activity using nucleation, aggregation and growth assay of calcium oxalate (CaOX) monohydrate crystals. The nucleation, aggregation and...

Author(s): Sushant Aryal, Puspa Kuwar and Chhitij Thapa  

Anti-hyperglycemic effects of Stemonocoleus micranthus (Fabaceae) stem bark on alloxan-induced hyperglycemic rats

April 2021

This study evaluated the anti-hyperglycemic potential of Stemonocoleus micranthus Harms. (Fabaceae) stem bark. Three models used in this study were: normoglycemic animal model, oral glucose tolerance test (OGTT) and alloxan-induced hyperglycemic model for acute and prolonged administration. Five (5) groups of rats (n=5) were used for all models; group 1 served as the control (received 2 ml/kg of distilled water; p.o.),...

Author(s): Florence N. Mbaoji, Collins A. Onyeto, Okechukwu O. Ndu, Bonaventure C. Obi and Akachukwu M. Onwuka  

Antibacterial effects of the organic crude extracts of freshwater algae of Sulaymaniyah, Kurdistan Region, Iraq

April 2021

In the recent past, the importance of freshwater algae has grown enormously due to their antibiotic activity against certain species of bacteria known for several disease states like endocarditis, external otitis, skin rash, etc. Also, there is a growing concern among the immunocompromised individuals that they may be susceptible to antibiotics and anti-fungal resistant infections resulting in increased fatality rates....

Author(s): Noel Vinay Thomas, Dlzar Dlshad Ghafour, A Salomy Monica Diyya, Rawa Raouf Ismail, and Lanya Karwan Jalal     

Antioxidant effect of Hymenaea courbaril L (Jatobá) sap on the healing of wounds on mice

April 2021

The use of natural products with curative action is a common cultural practice in the Brazilian Amazon, but little explored scientifically. The effect of Hymenaea courbaril L sap extract and its contribution to wound healing in mice was evaluated. The antioxidant potential of the extract was studied using the radical 1,1-diphenyl-2-picrilhidrazil and 2,2'-azino-bis (3-ethyl benzothiazoline-6-sulfonic) acid radical,...

Author(s): Ruth Silva Lima da Costa, David Smangoszevski Martins, Laan Diego Carvalho Peixoto, Bárbara Janaína Paula da Silva, Larissa Barbosa Borges, Emerson Silva Lima,  Hector Henrique Ferreira Koolen, Dionatas Ulises de Oliveira Meneguetti,  Ana Flávia Marçal Pessoa and Romeu Paulo Martins Silva  

Seasonal impacts on antifungal activity and chemical composition of extracts from medicinal plants Turraea holstii and Clausena anisata

April 2021

Curative dependence on season of harvest for medicinal plants is an alleged claim by traditional health practitioners. This study aimed to verify these claims by investigating antifungal activity and chemical profiles of two traditionally used medicinal plant species: Turraea holstii and Clausena anisata harvested in the rainy and dry seasons, with a view of establishing appropriate the season for optimal activity. The...

Author(s): Francis Machumi, Ester Innocent and Pius Yanda  

Farmers’ awareness and ethno-veterinary practices regarding porcine cysticercosis in the province of Boulkiemde, Burkina Faso

April 2021

Porcine cysticercosis is a major public health issue in Burkina Faso. This study investigated farmers’ awareness and ethno-veterinary practices regarding this disease in Boulkiemde province, Burkina Faso. A survey was done with 132 randomly selected pig farmers in 10 villages of two municipalities of Boulkiemde province, using a semi-structured questionnaire. The majority of interviewed farmers (54%) were from the...

Author(s): Laibané Dieudonné Dahourou, Almamy Konaté, Arnaud Stéphane Rayangnéwendé Tapsoba, Bénéwendé Aristide Kaboré, Adama Kabore, Hamidou Hamadou Tamboura and Amadou Traoré  

Chemical and organic fertilizer: The effect on apiin production by Petroselinum crispum var. neapolitanum Danert

March 2021

Parsley (Petroselinum crispum var. neapolitanum Danert) is a vegetable species with potential for pharmaceutical use because it contains apiin, a flavonoid that stands out for having biological activities, such as antioxidant. The aim of this study is to evaluate the influence of chemical or organic fertilizers on the nitrogen metabolism and production of flavonoids in parsley at different stages of development, aiming...

Author(s): Mylena Firmiano de Andrade, Luiziene Soares Alves, Bruna Cristina Borges Machado, Marco Andre Alves de Souza, Rosane Nora Castro, Douglas Siqueira de Almeida Chaves and André Marques dos Santos  

Chambá (Justicia pectoralis) syrup for the treatment of cough and respiratory symptoms: A randomized clinical trial

March 2021

Cough is a common pediatric complaint, resulting in frequent doctor’s office or hospital visits. In Brazil, the leaves of chambá (Justicia pectoralis) have been used extensively in herbal preparations for the treatment of many respiratory problems such as cough, bronchitis, and asthma. Thus, this study aimed to assess the effectiveness of chambá syrup for the treatment of cough and respiratory...

Author(s): Wilcare de Medeiros Cordeiro Nascimento, Francisco Plácido Nogueira Arcanjo, Mary Anne Medeiros Bandeira, Bruna Linhares Prado, Maria Ester Frota Fernandes, Elayne Cristina Oliveira Brito, Bianca Frota Monte, Aristides Avilo do Nascimento, Antonio Flávio Queiroz de Oliveira, Leandro Cordeiro Portela and Cecília Costa Arcanjo  

Toxicological evaluation of Zanthoxylum zanthoxyloides (Lam) Zepernick & Timler root bark used as biopesticide and medicine

February 2021

Toxicological studies were carried out to investigate the effect of consumption of Zanthoxylum zanthoxyloides root bark widely used in traditional medical practices and as protectant of stored cereal products in Nigeria, using albino rats. Serum, kidney and liver were tested for oxidation stress and tissue damage markers; aspartate amino transferase (AST), alanine amino transferase (ALT), urea, bilirubin and creatinine...

Author(s): Mohammed Gbate, Olufemi Michael Ashamo and Akinwande Lawrence Kayode  

Plants for veterinary use in the Montaña Palentina region (Palencia, Spain)

February 2021

Profound social changes that have occurred in recent decades in rural society have led to the abandonment of ethno veterinary practices and knowledge, traditionally used to treat and prevent animal diseases. The main objective of this ethno botanical work is to document the traditional veterinary uses of plants in the Montaña Palentina region (Palencia, Spain). The data obtained has been compiled through 139...

Author(s): Juan Cruz Pascual and Baudilio Herrero  

Aphrodisiac activity of ethanol extract and fractions of Fadogia cienkowskii Shweinf. Rubiaceae roots in albino rats

February 2021

Fadogia cienkowskii is a shrub whose roots are used in many communities of Northern Nigeria to improve sexual performance; however, there is no scientific study to verify this claim. This study determined the effect of 70% ethanol extract of F. cienkowskii roots and its fractions (ethyl acetate, n-butanol, and residual ethanol) on mating behaviour (mounting, intromission and ejaculation) and serum testosterone...

Author(s): Jurbe Gofwan Gotep, Sunday Yakubu Sabo, Sunday Makama, Mary Ogonnaya Uguru and Francis Kanayo Okwuasaba  

Qualitative and quantitative phytochemical profiling of crude fractions of Pechuel-Loeschea leubnitziae leaves

February 2021

Pechuel-Loeschea leubnitziae is a predominant medicinal plant in Namibia. It is traditionally utilized in treatment of gastrointestinal issues, sexually transmitted infections and common cold. Despite its therapeutic potential, the phytochemicals profile and compounds compositions are yet to be scientifically validated. This study was conducted to determine the spectrum and total phytochemical constituents present in P....

Author(s): Mariah Ndilimeke Muhongo, Mourine Kangogo and Christine Bii  

Occurrence of calcium oxalate crystals in some wild plants used in traditional medicine in Saudi Arabia

February 2021

Plants are widely used in traditional medicine, but could be detrimental to patients, due to the presence of some harmful substances such as calcium oxalate (CaOx) C2CaO4 crystals. The presence, morphology and distribution of CaOx crystals were investigated in 60 wild, herbal plant species from the Al Qussim Region, Saudi Arabia. This was done via light microscopy of transverse sections of stems and leaves using light...

Author(s): Mohamed El-Zaidy and Abdulaziz A. Alsahli  

Ethnomedical survey of plants used for the management of HIV and AIDS-related conditions in Mbulu District, Tanzania

January 2021

The aim of this Study was to document medicinal plants used in the management of HIV and AIDS-related conditions in Mbulu District. An ethnomedical survey was conducted using a semi-structured questionnaire. The main HIV and AIDS-related conditions considered during this study were; cough, frequent fevers, diarrhea, weight loss, oral thrush, genital warts, candidiasis, abscesses, skin rashes, shingles and venereal...

Author(s): Alphonce Ignace Marealle, Mainen Moshi, Ester Innocent, Michael Qwarse and Kerstin Andrae-Marobela  

Chemical composition and antibacterial activity against Escherichia coli of extracts of a common household plant

January 2021

Plants have long been a source for a wide variety of compounds with medicinal properties; of significant interest are plant antimicrobial compounds. Given the continual increase in bacterial resistance, it is imperative that new antimicrobial compounds need to be discovered. The purpose of this study was to screen some common household plants for antibacterial activity, specifically against Escherichia coli. Leaves of...

Author(s): Maria K. Kozar, Joanna G. Kondylis, Katerina A. Drouvalakis and Leland G. Kozar  

Development and validation of a new method to quantify vitexin-2''-O-rhamnoside on Passiflora L. extracts

January 2021

The genus Passiflora L. is the most representative of the Passifloraceae family and includes about 500 species. The aim of this work was to analyze three different passion fruit species in relation to vitexin-2´´-O-rhamnoside content by high-performance liquid chromatography coupled to a diode-array ultaviolet detector. Samples were prepared by water infusion (10% w/v), dried by lyophilization, and stored in...

Author(s): Lorenna C. da Rosa, Monica R. P. Siqueira, Francisco J. R. Paumgartten, Georgia Pacheco, Elisabeth A. Mansur de Oliveira and Davyson de L. Moreira,  

Ethnobotanical study of selected medicinal plants used for the treatment of respiratory diseases in Southern Brazil

January 2021

This survey explored the ethnobotanical uses of selected medicinal plants; Adiantum raddianum C. Presl. (Pteridaceae), Lippia alba (Mill.) N. E. Brown (Verbenaceae) and Coronopus didymus (L.) Sm. (Brassicaceae) used for respiratory diseases in Southern Santa Catarina (Brazil). This is timely as the incidence of respiratory disease is increasing in this state. Information was obtained through both interviews using a...

Author(s): Marília Schutz Borges, Michele Darós Freitas, Paula da Silva Cardoso, Vanilde Citadini- Zanette, Silvia Dal Bó and Patrícia de Aguiar Amaral  

The study on antioxidant activity of ulvan-calcium derivative

January 2021

Ulvan is a water-soluble polysaccharide that is extracted from the algae Ulva pertusa (Chlorophyta). In this study, ulvan-calcium derivative (U-calcium) was prepared and calcium content was 5.2%. Ulvan-calcium could effectively scavenge on 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2’-azino-bis (3-ethyl-benzothiazolie-6-sulfonic acid) (ABTS), hydroxyl, and superoxide radicals. The inhibition rate on superoxide...

Author(s): Xiaoqian Wang, Yuzhou Wan, Lin Liu, Haiting Xu, Junying Zou, Siming Liang, Chen Yang and Huimin Qi  

Myrothamnus flabellifolius attenuates streptozotocin-high energy diet-induced type 2 diabetes in male sprague dawley rats

December 2020

Several medicinal plants have anti-diabetic properties and can be considered as an alternative therapy because of their actions which are like those of conventional antidiabetic drugs. In this study, we investigated Myrothamnus flabellifolius (MF) ethanol: water (70:30) extract for its possible anti-diabetic potential in streptozotocin-high energy diet (STZ-HED) induced type 2 diabetes mellitus (T2DM) rats and its...

Author(s): Tebogo Elvis Kwape, Padmaja Chaturvedi, Goabaone Gaobotse, Kabo Masisi, Keagile Bati and Runner Majinda  

Inhibitory effects of Anadenanthera colubrina (Vell.) Brenan stem bark extract on α-glucosidase activity and oxidative stress

November 2020

In this study, we investigated the promising potential of Anadenanthera colubrina bark extract (BEAc) as a product to combat diabetes mellitus (DM). We evaluated the inhibitory effects of BEAc on α-glucosidase and the oxidation of biomolecules, as well as its main phytoconstituents. In terms of free radical scavenging, BEAc exhibited a dose-effect relationship. BEAc was more efficient than rutin and butylated...

Author(s): Odelio Joaquim da Costa, Robson dos Santos Barbosa, Ilsamar Mendes Soares, Eber Euripedes de Souza, Luís Fernando A. Gellen, João Pedro Pereira P. Lemos, Raimundo Wagner S. Aguiar, Adão Lincon B. Montel and Sérgio Donizeti Ascêncio  

Lavandula angustifolia aqueous extract ameliorates anxiety and depressive-like behaviors in chronic mild stress-treated male rats

November 2020

The study aims to show the possible anxiolytic and antidepressant-like properties of an oral lavender’s flower aqueous extract (LAE) in chronic mild stress (CMS) model of rats. Test and control rats received LAE (200 or 400 mg/ kg) and distilled water respectively. Tests of Sucrose preference (SP), elevated plus maze (EPM), and open field (OFT) were used to evaluate rats’ behavioral changes.  The...

Author(s): Mir Behrad Aghazadeh Ghadim, Asma Neisy, Mohsen Sisakht and Zahra Khoshdel ⃰  

In vitro antioxidant and cytotoxic activity of the root extract of Aspilia mossambicensis (Oliv) Wild (Asteraceae)

November 2020

Aspiliamossambicensis(Oliv) Wild is used by Traditional Health Practitioners in northeastern Tanzania, for treatment of cancers. In order to evaluate these claims root powder of the plant was extracted with dichloromethane: methanol (1:1), followed by vacuum liquid chromatography fractionation to obtain dichloromethane, ethyl acetate and methanol fractions which were screened for brine shrimp toxicity and antioxidant...

Author(s): Daniel Zacharia Matata, Olipa David Ngassapa, Mainen Julius Moshi, Francis Machumi, Kenneth Oosthuizen, Bresler Swanepoel, Luanne Venables, Trevor Koekemoer, Matthias Heydenreich, Paul Erasto Kazyoba and Maryna van de Venter

Evaluating the antibacterial, antioxidant and wound healing properties of the stem bark extract of Khaya grandifoliola (Welw) CDC (Meliaceae) (African mahogany)

November 2020

The study was conducted to evaluate the antibacterial, antioxidant, and wound healing properties of the stem bark of Khaya grandifoliola (Welw) CDC (Meliaceae). A preliminary phytochemical screening conducted showed the presence of tannins, alkaloids, saponins, reducing sugars, flavonoids, terpenoids, and phenols in the stem bark (KG) as well as its ethanol extract (KGE). The antibacterial activity of KGE was evaluated...

Author(s): Anna Kwarley Quartey, Emmanuel Orman, Nana Ama Mireku-Gyimah, Phoebe Esinam Goku, Fadila Alidu and Linda Owusu Boateng  

Phytochemical screening and antimicrobial activity of methanol extract of Garcinia Kola Heckle fruit mesocarp

November 2020

The phytochemical screening and antimicrobial activities of the methanol extract of Garcinia kola fruit mesocarp were investigated against four bacteria and two fungi in the study. The extract was investigated for the presence of phytochemicals using standard phytochemical screening methods. The results revealed the presence of flavonoids, tannins, alkaloids, terpenoids, cardiac glycosides, and reducing sugar. The...

Author(s): Ali Ibeabuchi Jude, Adonu Cyril Chekwube and Okorie Ndidiamaka Hannah

Future molecular medicine from white frangipani (Plumeria alba L.): A review

October 2020

White frangipani (Plumeria alba L.) is tropical and subtropical plants, have been familiar used in many traditional medication as well as aromatherapy, especially for the flower part. Scientific study, but was not so many, reporting some pharmacological and toxicological effects of this plant which lead to more depth study at molecular level. This review describes the pharmacological and toxicological effect of the...

Author(s): Barry Anggoro, Enade Istyastono and Maywan Hariono  

Evaluation of antioxidant and protective effect against genotoxic damage of two extracts of chaya leaves (Cnidoscolus aconitifolius)

October 2020

Stress, excessive consumption of processed foods, pollutants and many other factors of today's life have caused oxidative stress in our body and damage to genetic material in our cells, leading to diseases such as diabetes, hypertension, cancer, metabolic syndrome, among others. Medicine has returned to take up traditional remedies mainly in plants. Chaya (Cnidoscolus aconitifolius) has been studied in this regard,...

Author(s): Eduardo Lozano Guzmán, Christian Tadeo Badillo Castañeda, Lourdes Garza Ocañas, María Guadalupe Nieto Pescador, Francisco Javier Moreno Cruz and José Luis  Ríos Bañuelos  

Antibacterial activities of ethyl acetate and methanol leaf extracts of Psidium guajava and Carica papaya on bacterial pathogens isolated from manual toothbrushes

October 2020

Toothbrush has become a potential source of infection, owing to contamination by various pathogens as a result of poor oral hygiene awareness and practices. This study investigated the antibacterial activities of ethyl acetate and methanol leaf-extracts of Psidium guajava (guava) and Carica papaya (paw-paw) on bacteria pathogens isolated from toothbrushes. A total of 100 manual used toothbrushes of different brands were...

Author(s): Ani S. E., Iroha I. R., Moses I. B., Ugbo E. N., Nwakaeze E. A., Okoli S. C., Brownson G. E., Ngwu J. N., Omale J. J., Okorie C. C., Mohammed D. I., Igwe O. F., Dieke A. J., Ezugworie F. N. and Agbo E. E.    

Larvicide and repellent activity of Hypenia irregularis (Benth.) Harley in the alternative control of mosquito Aedes aegypti

October 2020

Dengue is an emerging epidemic disease and among those transmitted by the Aedes aegypti mosquito, it is the one with the highest number of cases and cases with death. With the wide dissemination of the beneficial effects of medicinal plants and the use in agriculture as a pesticide, studies on the prospection of plants with toxic activity have been increasing, highlighting extracts and essential oils. The objective of...

Author(s): Richard Dias Possel, Talita Pereira de Souza Ferreira, Douglas Martins de Oliveira Bessa, Marcela Oliveira Ferreira, Diego Patrick Nusrala Dias, Gleys Kellen Aquino Moraes, Luana Fernandes Ferraz, Taciano Peres Ferreira, Ana Claudia Fernandes, Julcemar Didonet, Gil Rodrigues dos Santos, Bruna Letícia Dias, and Raimundo Wagner de Souza Aguiar    

Eerdun Wurile protects neuron and promotes neurite outgrowth through regulation of apoptotic gene expression in PC-12 cells

October 2020

Eerdun Wurile (EW) is one of the most widely used traditional Mongolian medicines for stroke recovery. Previous studies revealed that EW regulates brain gene expression in a rat model of middle cerebral artery occlusion (MCAO). However, the fraction of active components and the specific genes regulated by such fractions have not been elucidated clearly. The study shows that the extracts of EW regulate the expression of...

Author(s): Chu La, Tsogzolmaa Ganbold, Saren Gaowa, Qiburi Qiburi, Temuqile Temuqile and Huricha Baigude  

Anticonvulsant activities of friedelan-3-one and n-dotriacontane both isolated from Harungana madagascariensis Lam (Hypericaceae) seeds extracts

October 2020

Chemical investigation of the crude methanol/methylene chloride (1:1) extract of the seeds of Harungana madagascariensis resulted in the isolation of two known compounds namely n-dotriacontane and friedelan-3-one. The structures of the isolated compounds were determined on the basis of 1D NMR spectroscopy and comparison with literature data. The crude extract and the two compounds were evaluated for their anticonvulsant...

Author(s): Jordan Kache Signe, Godfred Ayimele Aponglen, James Mbah Ajeck and Germain Sotoing Taiwe

Optimization by mixture design of the antimicrobial activities of five selected essential oils

October 2020

The individual antimicrobial activities of essential oils have been reported by many authors. However, there is little information about the effects of their mixtures in order to maximize their effect and reduce the growing resistance of pathogens to existing medicines. So, the aim of this work is to optimize the antibacterial and antifungal activities of essential oils from Plectranthus glandulosus, Ocimum gratissimum,...

Author(s): Mikolo Bertin, Moyen Rachel, Baloki Ngoulou Tarcisse and Nguimbi Etienne  

Hypoglycaemic effects of Salvia officinalis extracts on alloxan-induced diabetic Swiss albino mice

October 2020

Diabetes mellitus is the fourth killer disease globally. The available management strategies are quite expensive and sometimes unsafe. This necessitates the need for bio-active drugs from medicinal plants. Although Salvia officinalis (sage) is used in herbal medicine, the scientific validation for anti-diabetic effects of various extracts has been elusive. The present study aimed to determine and compare the...

Author(s): Kanana Faith Mbiti, Maina Charles Mwendia, Kibet Joseph Mutai and Clement Josphat Matasyoh  

Chemo preventive effect of methanol extract of Anacardium occidentale nut shell on ultra-violet radiation induced skin damage

September 2020

Anacardium occidentale nut shell liquid has been used for decades especially by natives of South America, Asia and Africa in the treatment of topical skin diseases, abrasion and cancerous ulcers amongst others. Chronic exposure to sunlight can lead to skin damages including erythema, edema, hyperplasia, formation of sunburn cells, photo-aging, suppression of the immune system and skin cancer. This study was aimed at...

Author(s): Pepple N. M. , Ekoriko W. U., Idih F. M. and Chidozie V. O.  

Ethnobotanical study of plants used against onchocerciasis in the far north region of Cameroon

September 2020

Despite the multitude of studies which have shown the use of medicinal plants in the management of parasitic diseases, little data was available on the plants used against onchocerciasis. Ethnobotanical surveys were carried out among traditional healers in the Far North region of Cameroon. Studies were conducted from July 2017 to May 2018 through direct interviews using a semi-structured questionnaire taking into...

Author(s): Amina Mamat, Zambou Zebaze Leïla, Ndjib Rosette Christelle, Nguezeye Yvette, Kenne Meli Phalone, Okah-Nnane Ndode Herman, Bitja Nyom Roger Arnold and Ndjonka Dieudonne  

In vitro antibacterial activity of Psidium guajava (Guava) leaves extract on carbapenem-resistant Klebsiella pneumoniae causing multi-drug resistant systemic infections

September 2020

Systemic bacterial infections affect almost all part of the human body systems leading to infections such as urinary tract infections, septicemia, meningitis, pneumonia, peritonitis and gastritis. Carbapenems have been used as drug of choice in the treatment of systemic infections. Studies have indicated that Enterobacteriaceae are producing enzymes such as carbapenemases, which inactivate carbapenems.  There ...

Author(s): Henry Kwadwo Hackman, Reuben Essel Arhin, Bright Kojo Azumah, David Boateng, Blessing Nwosu and Mark Apenteng  

Protective effect of piperine from Piper chaba fruits on LPS-induced inflammation in human intestinal cell line

September 2020

Piper chaba is a flowering vine in the family of piperaceae. It is a spicy plant widely used as food and herbal medicine in the South and Southeast Asian countries. The study evaluated anti-inflammatory and immunomodulatory activities of a major alkaloid extract, piperine, from P. chaba fruits on human colonic epithelial cells. The effects of piperine extract on cell viability, pro-inflammatory cytokine inhibition, and...

Author(s): Anyanee Buagaew and Natwadee Poomipark  

Antibacterial, total phenols, antioxidant, and fatty acids of the lyophilized body fat of Podocnemis expansa (Schweigger, 1812) from farm in Acre State, Brazil

September 2020

Podocnemis expansa (Podocnemididae) is a chelonian of suborder Pleurodira and is popularly known as Amazon turtle. The animal’s body fat was removed from the farm in Xapuri city in Acre State, Brazil. The fat was lyophilized and the oil was extracted by the Soxhlet method using hexane, as a solvent. The fatty acids majority, identified and quantified by gas chromatography-flame ionization detector, were:...

Author(s): Brazil M. V. da S., Souza M. de B., Ferraz V. P., Martins B. A., De Carvalho Neto M. F., De Melo A. C. G. R., Ribeiro P. R. E. and De Melo-Filho A. A.

Screening open source traditional Chinese medicine extracts for growth-inhibiting properties towards Acinetobacter baumannii

September 2020

Infections caused by Acinetobacter baumannii and other pathogenic bacteria are a worldwide concern due to their increasingly prevalent multidrug resistance. World leaders and health organizations across the globe have voiced their concerns over antibiotic resistance and the critical need for the development of novel antibiotics. Although the number of new antibiotic drugs entering the marketplace in recent years has...

Author(s): Lucas Poon, Thomas J. Langowski, Mozna H. Khraiwesh, Malik J. Raynor, Jesse P. Deluca, Jeffrey R. Livezey, Thomas G. Oliver, Susan Ensel, Tanja Grkovic, Barry R. O’Keefe, and Patricia J. Lee  

Medicinal plants used against malaria by traditional therapists in malaria endemic areas of the Ségou region, Mali

September 2020

West Africa is one of the regions in Africa with the highest levels of malaria transmission a descriptive study was carried out to inventorise the medicinal plants traditionally used against malaria by traditional therapists in five malaria endemic areas of the Ségou region, in Mali. Sixty-five traditional therapists were randomly selected to be part of the study. Questions were posed using semi-structured...

Author(s): Jean Noël KEÏTA, Nouhoum DIARRA, Donatien KONE, Hassana TOUNKARA, Fousseyni DEMBELE, Moustapha COULIBALY  and Nah TRAORE

Larvicidal activity of Juniperus procera extract against anopheles mosquito in in vitro, North Western Ethiopia

September 2020

Mosquitoes are the major health threat as they transmit plasmodium parasites that cause malaria. Since mosquitoes developed resistances towards insecticides, investigators are searching for alternative control measures. Bioactive plant chemicals have been identified to serve as a defense mechanism against insects’ larvae. Therefore, the aim of the study was to evaluate larvicidal activities of Juniperus procera...

Author(s): Wondimu Ersino, Hirpasa Teressa and Tadele Alemayo  

Ethnobotanical survey of medicinal plants commonly used in snakebites in North Western Nigeria

September 2020

The incidence of snake bite in rural West Africa is reportedly high with an 11–17% mortality rate. Nigeria has one third of the cases for snake bite cases in this region.Thus, most tribes in North-western part of Nigeria depend on medicinal plants for snakebites. However, it appears that a gap exists on documentation of these plants especially tropical flora used in the management of snake bite. This led to...

Author(s): Ibrahim-Maigandi Hassan, Aishatu Shehu, Abdulkadir Umar Zezi, Mohammed Garba Magaji and Jamilu Ya’u  

Phytochemical screening and antibacterial activity of dried pods of Prosopis Africana

August 2020

Evolving resistant microbial strains have posed a great challenge on antibacterial chemotherapy in recent times. Search for novel antimicrobial agents has therefore remained a highly prospective area of research, especially those of plant origin. To this end, Prosopis africana pod used in West Africa in traditional medicine was evaluated for phytochemical constituents using standard procedures. Antibacterial activity...

Author(s): Baturh Yarkwan  

Determination of total phenolic compounds, antioxidant activity and nutrients in Brazil nuts (Bertholletia excelsa H. B. K.)

August 2020

Bertholletia excelsa is native to the Amazon, and it grows in the forests that border the great rivers of the Amazon. This tree brings interest in the commercialization of its fruit, which is called the urchin and almond. Bertholletia excelsa has antioxidant properties, and it is rich in phenolic compounds. In this research, the antioxidant capacity of the Brazilian nut from the city of São João da Baliza...

Author(s): Selvin Antonio Saravia Maldonado, Ismael Montero Fernández, Ricardo Santos Alemán, Jhunior Abrahan Marcia Fuentes and María da Conceição Campelo Ferreira  

Effect of Aloe resin on cell migration between Scratch and Boyden chamber assays

August 2020

Effect of herbal medicine on cell migration is one of the therapeutic points. The objective of this study was to compare the Scratch assay with the Boyden chamber assay for evaluating cell migration with Aloe resin as the chemoattractant agent. Human gingival fibroblasts cells (2.5×105 cells/ml) were exposed to 0.02% (w/v) of Aloe resin in 6-well culture plates for the Scratch assay or in 24-transwell-culture...

Author(s): Suwanna Korsuwannawong, Ratchaporn Srichan and La-Ongthong Vajrabhaya  

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