Cadmium (Cd) is present in many agricultural soils, and consequently can be absorbed for species as corn and wheat. The studied areas were Central-North, Central, Central-south and South of the country, in a transect of 1,500 km long. In soils from 40 different sites were sampling in two depths. In these areas corn and wheat are important crops. Total cadmium, extractable acid (DTPA) and water soluble fractions of cadmium was determined. The results indicated that Cd concentrations showed differences among geographic areas, observing the highest Cd total concentration in the Southern area, and the highest DTPA Cd content in the North-central area. Differences between soil depths were also detected, describing the highest concentration in the upper part of the soil. Additionally, Cd concentrations were correlated with different physico-chemical soil properties. Organic matter and exchangeable aluminum were correlated with total Cd; exchangeable calcium and available Zinc with DTPA Cd; and exchangeable Magnesium with soluble Cd. The results of the study reported that the total Cd concentration in the study areas was lower than what is considered critical in agricultural areas, while DTPA Cd concentrations were lower than those reported for other agricultural areas of the world.