African Journal of
Agricultural Research

  • Abbreviation: Afr. J. Agric. Res.
  • Language: English
  • ISSN: 1991-637X
  • DOI: 10.5897/AJAR
  • Start Year: 2006
  • Published Articles: 6900

Full Length Research Paper

Mitotic response of Allium cepa L. to toxicity of pharmaceutical effluents

Emmanuel Obiora Udoh
  • Emmanuel Obiora Udoh
  • Department of Plant Science and Biotechnology, University of Nigeria, Nsukka, Enugu State, Nigeria
  • Google Scholar
Sheily Nneka Egonu
  • Sheily Nneka Egonu
  • Department of Plant Science and Biotechnology, University of Nigeria, Nsukka, Enugu State, Nigeria
  • Google Scholar
Nnaemeka Maduabuchi Eze
  • Nnaemeka Maduabuchi Eze
  • Department of Plant Science and Biotechnology, University of Nigeria, Nsukka, Enugu State, Nigeria
  • Google Scholar
Ngozi Eucharia Abu
  • Ngozi Eucharia Abu
  • Department of Plant Science and Biotechnology, University of Nigeria, Nsukka, Enugu State, Nigeria
  • Google Scholar
Godswill Chukwunonso Ajuziogu
  • Godswill Chukwunonso Ajuziogu
  • Department of Plant Science and Biotechnology, University of Nigeria, Nsukka, Enugu State, Nigeria
  • Google Scholar
Maryrose Chigozie Nwankwo
  • Maryrose Chigozie Nwankwo
  • Department of Plant Science and Biotechnology, Michael Okpara University of Agriculture Umudike, Abia State, Nigeria.
  • Google Scholar
Nnamdi Ogwo
  • Nnamdi Ogwo
  • Department of Plant Science and Biotechnology, Michael Okpara University of Agriculture Umudike, Abia State, Nigeria.
  • Google Scholar
Eugene Obashi Ojua
  • Eugene Obashi Ojua
  • Department of Plant Science and Biotechnology, University of Nigeria, Nsukka, Enugu State, Nigeria
  • Google Scholar
Goodness Okeh
  • Goodness Okeh
  • Department of Plant Science and Biotechnology, University of Nigeria, Nsukka, Enugu State, Nigeria
  • Google Scholar


  •  Received: 12 March 2021
  •  Accepted: 02 June 2021
  •  Published: 30 June 2023

References

Abu NE, Mba KC (2011). Mutagenecity testing of phamarceutical effluents on Allium cepa root tip meristems. Journal of Toxicology and Environmental Health Sciences 3(2):44-511.

 

Abu NE, Asomba CO, Ubani C (2015). Chemical composition and mutagenic assessment of petrochemical effluents on onion (Allium cepa) root tip mitosis. African Journal of Biotechnology 14(38):2740-2747.
Crossref

 

Akaneme FI, Iyioke IV (2008). Mutagenic potentials of the sterilizing fluid - Purital on root tip mitosis of Allium cepa. Bio - Research 6(1):293-297.
Crossref

 

American Public Health Association, (APHA) (1998). Standard methods for examination of water and wastewater. 20th ed. American Public Health Association, Washingto DC.
Crossref

 

American Public Health Association (APHA) (2005). Standard Methods for the Examination of Water and Wastewater (21st ed.). American Public Health Association. Washington, DC.

 

Anila M, Ditika K (2015). The use of Allium cepa L. assay for toxicity bio-monitoring of hospital effluents - an albanian case. European Journal of Toxicological Sciences 1:1-15

 

Antonsie-Wiez D (1990). Analysis of cell cycle in the root meristem of Allium cepa under the influence of Leda Krin, folia Histochem. Cytobiology 28(1-2):79-95.

 

Babatunde BB, Bakare AA (2006). Genotoxicity screening of wastewaters from Agbara Industrial Estate, Nigeria evaluated with the Allium test. Pollution Research 25(2):227-234.

 

Bakare AA, Lateef A, Amud OS, Afokbi RO (2003). The aquatic toxicity and characterization of chemical and microbiological constituents of water sample from oba river, odo-oba, Nigeria. Journal of Microbiology Biotectnology and Environmental Science 5(1):11-19.

 

Bakare AA, Okunola AA, Adetunji OA, Jenmi HB (2009). Genotoxicity assessment of a pharmaceutical effluent using four bioassays. Genetics and Molecular Biology 32(2):373-381.
Crossref

 

Bruning T, Chronz C (1999). Occurance of urinary tract tumour's in miners highly exposed to dimtroluene. Journal of Occupational and Environmental Medicine 43(3):144-149.
Crossref

 

Dash S, Panda KK, Pada BB (1998). Biomonitoring of low levels of mercurial derivatives in water and soil by Allium micronucleus assay. Mutation Research 203(1):11-21.
Crossref

 

El-Shahaby OA, Abdel HM, Soliman MI, Mashaly IA (2005). Genotoxicity screening of industrial wastewater using the Allium cepa chromosome aberration assay. Pakistan Journal of Biological Science 6(1):23-28.
Crossref

 

Fiskesjö G (1985). Allium test on river water from Braan and Sexan before and after closing of a chemical factory. Ambiologia 14:99-103.

 

Fiskesjö G (1993). The Allium test in wastewater monitoring. Environmental Toxicology and Water Quality 8(3):291-298.
Crossref

 

Gadipelly C, Perez-Gonzalez A, Yadava GD, Marathe KV (2014). Pharmaceutical industry waste water: Review of the Technologies for water treatment and recise. Industrial and Engineering chemistry Research 53(29):11571-11592.
Crossref

 

Grover IS, Kaur S (1999) Genotoxicity and wastewater samples form sewage and industrial effluent detected by the Allium root anaphase aberration and micronucleus assays. Mutation Research 426(2):183-188.
Crossref

 

Hernandoa MD, Mezcua M, Fernandez-Alba AR, Barcelona D (2006) Environmental risk assessment of pharmaceutical residue in waste water effluents, surface waters and sediments. Talanta 69(2):334-342.
Crossref

 

Ibeh O, Umeham N (2018). Genotoxicity assessment of three industrial effluents using the Allium cepa bioassay. African Journal of Environmental Science and Technology 12(3):115-122.
Crossref

 

Jiang BH, Rue E, Wang GL., Roe R, Semenza GL (1996). Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1. Journal of Biological Chemisry 271(30):17771-17778.
Crossref

 

Lateef A, Ufuoma PE, Yekeen TA (2007). Bacteriology and genotoxicity of some pharmaceutical wastewaters in Nigeria. International Journal of Environmental Health 1(4):207-218.
Crossref

 

Majer BJ, Grummt T, Uhi M, Knasmuller S (2005). Use of plant assays for the detection of genotoxins in the aquatic environment. Acta of Hydrochemistry and Hydrobiology 33(1):45-55.
Crossref

 

Odeigah PGC, Nurudeen O, Amund OO (1997) Genotoxicity of oil field wastewater in Nigeria. Hereditas 126(2):161-167.
Crossref

 

Olaitan OJ, Sulola EO, Ademoju EO, Omoloye AA (2015). Cytotoxic effects and genotoxic screening of pharmaceutical effluents using onion bulbs (Allium cepa). Journal of Advance in Biology and Biotechnology 2(1):51-58.
Crossref

 

Olaitan OJ, Sulola EO, Kasim LS, Daodu JO (2014). Physico-chemical characteristics of pharmaceutical effluents from Sango industrial area, Nigeria. Bulletin of Environment, Pharmacology and Life Sciences 3(10):78-81.

 

Olorunfemi DI, Okieimen EA, Muokebe I (2015). Evaluation of bilge water-induced plant genotoxicity using randomly amplified polymorphic DNA (RAPD). Ife Journal of Science 17(1):121-129.

 

Olorunfemi DI, Okoloko GE, Bakare AA, Akinboro A (2011). Cytotoxic and genotoxic effects of cassava effluents using the Allium cepa test. Research Journal of Mutagenesis 1(1):1-9.
Crossref

 

Panda BB, Sahu UK (1985) Induction of abnormal spindle function and cytokinesis inhibition in mitotic cells in Allium cepa by organophosphorus insecticides fensulfothion. Cytobios 42(167-168):147-155.

 

Patel M, Kumar R, Kishor K, Mlsna T, Pittman C, Mohan D (2019). Pharmaceuticals of emerging concern in aquatic systems: chemistry, occurrence, effects, and removal methods. Chemical Reviews 119(6):3510-3673.
Crossref

 

Patneedi CB, Parasadf KD (2015) Impact of pharmaceutical wastes on human life and environment. Rasayan Journal of Chemistry 8(1):61-70.

 

Paz M, Muzio H, Mendelson A, Magdaleno A, Tornello CB, Moretton NJ (2006) Evaluation of Geno-toxicity and Toxicity of Buenos Aires City Hospital Wastewater Samples. Journal of Brazilian Society of Eco-Toxicology 1:1-6.
Crossref

 

Pedrazzani R, Ceretti E, Zerbini I, Casale R, Gozio E, Bertanza G, Gelatti U, Donato F, Feretti D (2014) Biodegradability, Toxicity and Mutagenicity of Detergents: Integrated Experimental Evaluations. Eco-toxicology and Environmental Safety 84:274-281.
Crossref

 

Perrodin Y, Christine B, Sylvie B, Alain D, Jean-Luc BK, Cécile CO, Audrey R, Elodie B (2013). A priori assessment of eco-toxicological risks linked to building a hospital. Chemosphere 90:1037-1046.
Crossref

 

Sumpter JP (2005) Pharmaceuticals in the environment: moving from a problem to a solution. In: K. K ummere, M, Hempel (eds) Green and sustainable pharmacy. Springer-Verlag Berlin Heidelberg, pp. 11-22.
Crossref

 

Ukaegbu MA, Odeigah GA (2009). The genotoxic effect sewage effluent on Allium cepa. Report and Opinion 1(6):36-41.

 

United States Environmental Protection Agency (USEPA) (2006). Acid digestion of sediments, sludge and soils. Methods - 305Ob. USEPA: Washington DC.

 

Urama DC, Ojua EO, Adeosun CA, Akaye MP, Agbo OB, Omeje MK (2020). Phytoconstituent evaluation of Jackfruit and its genotoxic effect using Allium sativum assay. Bioscience Research 17(4):2377 - 2382.

 

Wang W, Wang A, Chen L, Liu Y, Sun R (2002). Effect of pH on survival, phosphorus concentration, adenylate energy charge and Na+ - K+ ATPase activity of Penaeus chinensis Osbeck Juveniles. Aquatic Toxicology 60(1-2):75-83.
Crossref