African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12480

Short Communication

Glycyrrhizin therapy for viral infections

Kei Numazaki
Department of Pediatrics, Sapporo Medical University, School of Medicine, Sapporo, Hokkaido, 060-8543, Japan.
Email: [email protected]

  •  Accepted: 26 September 2003
  •  Published: 31 October 2003

Abstract

 

Glycyrrhizin (GL) was reported as the most active in inhibiting replication of the severe acute respiratory syndrome (SARS)-associated coronavirus. Therapeutic effect of GL for liver dysfunction associated with cytomegalovirus (CMV) infection in immunocompetent individuals was evaluated. Liver dysfunction in 4 cases improved and CMV disappeared from urinary samples after administration of GL intravenously by the age of 12 months. GL treatment also should be applied for the patients with SARS.

 

Key words: Glycyrrhizin, SARS, cytomegalovirus.  

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This article is published under the terms of the Creative Commons Attribution License 4.0

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