African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12501

Short Communication

Effect of Trimeresurus albolabris (green pit viper) venom on mean corpuscular volume, osmotic fragility and red blood cell morphology: A preliminary report

Suphan Soogarun, Montri Chowbumroongkait2, Paweena Pradniwat1, Supantitra Chanprasert1, Viroj Wiwanitkit3, Yaninart Suwanawong1, Tusrin Moungkote1 and Jaturawat Pawinwongchai1
  1Clinical Microscopy Research Unit, Department of Clinical Microscopy, Faculty of Allied Health Sciences, Chulalongkorn University, Thailand. 2 Snake farm, Thai Red Cross, Thailand. 3Department of Laboratory Medicine, Faculty of Medicine, Chulalongkorn University, Thailand.
Email: [email protected]

  •  Accepted: 20 April 2007
  •  Published: 31 May 2007

Abstract

 

An in vitro study was conducted by mixing small amounts of green pit viper venom with blood and observing changes. At a concentration of 10 mg crude venom, red blood cells (RBC) osmotic fragility slightly increased. RBC morphology changed to spherical shape which was compatible with what was observed in scanning electron microscope (SEM). However, there was no change in mean corpuscular volume (p > 0.05).

 

Key words: Green Pit Viper, Mean Corpuscular Volume (MCV), Osmotic Fragility.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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