African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12269

Review

Y-Chromosome short tandem repeat, typing technology, locus information and allele frequency in different population: A review

Muhanned Abdulhasan Kareem
  • Muhanned Abdulhasan Kareem
  • Babylon University, Centre of Environmental Research, Hilla City, Iraq.
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Ameera Omran Hussein
  • Ameera Omran Hussein
  • Department of Molecular Biology, Babylon University, Hilla City, Iraq.
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Imad Hadi Hameed
  • Imad Hadi Hameed
  • Department of Molecular Biology, Babylon University, Hilla City, Iraq.
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  •  Received: 29 January 2015
  •  Accepted: 29 June 2015
  •  Published: 14 July 2015

Abstract

Chromosome Y microsatellites seem to be ideal markers to delineate differences between human populations. They are transmitted in uniparental and they are very sensitive for genetic drift. This review will highlight the importance of the Y- Chromosome as a tool for tracing human evolution and describes some details of Y-chromosomal short tandem repeat (STR) analysis. Among them are: microsatellites, amplification using polymerase chain reaction (PCR) of STRs, separation and detection and advantages of X-chromosomal microsatellites.
 
Key words:  Forensic, population, review, STR, Y- chromosome.
 

Abbreviation

STR, Short tandem repeat; PCR, polymerase chain reaction; SSRs, simple sequence repeats; PAGE, polyacrylamide gel electrophoresis; CE, capillary electrophoresis; SNP, single nucleotide polymorphism; Y-DNA, Y-chromosome DNA; mtDNA, mitochondrial DNA.