Chromosome Y microsatellites seem to be ideal markers to delineate differences between human populations. They are transmitted in uniparental and they are very sensitive for genetic drift. This review will highlight the importance of the Y- Chromosome as a tool for tracing human evolution and describes some details of Y-chromosomal short tandem repeat (STR) analysis. Among them are: microsatellites, amplification using polymerase chain reaction (PCR) of STRs, separation and detection and advantages of X-chromosomal microsatellites.
Key words: Forensic, population, review, STR, Y- chromosome.
STR, Short tandem repeat; PCR, polymerase chain reaction; SSRs, simple sequence repeats; PAGE, polyacrylamide gel electrophoresis; CE, capillary electrophoresis; SNP, single nucleotide polymorphism; Y-DNA, Y-chromosome DNA; mtDNA, mitochondrial DNA.