African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12479

Full Length Research Paper

In vitro antifungal activity of methanol extracts of some Indian medicinal plants against pathogenic yeast and moulds

    Jigna Parekh and Sumitra Chanda*
Phytochemical, Pharmacological and Microbiological Laboratory, Department of Biosciences, Saurashtra University, Rajkot 360 005, Gujarat, India.
Email: [email protected]

  •  Accepted: 17 December 2007
  •  Published: 03 December 2008

Abstract

 

 

The methanol extract of 9 Indian medicinal plants belonging to 9 different families were evaluated for in vitro antifungal activity against some yeasts including Candida albicans(1) ATCC2091, C. albicans (2) ATCC18804, Candida glabrata NCIM3448, Candida tropicalis ATCC4563, Cryptococcus luteolus ATCC32044, Cryptococcus neoformansATCC34664, Trichosporon beigelli NCIM3404, and some moulds such as Aspergillus candidus NCIM883, Aspergillus flavus NCIM538, Aspergillus niger ATCC6275 andMucor heimalis NCIM873. The in vitro antifungal activity was evaluated at three different concentrations by agar disc diffusion method and the activity obtained was not concentration dependent. A. flavus was the most susceptible fungal strain while C. glabrata was the most resistant one. Saussurea lappa showed the best antifungal activity. The results were compared with the standard antifungals.

 

Key words: medicinal plants, antifungal activity, methanol extracts, yeast, mould,Saussurea lappa.
 

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This article is published under the terms of the Creative Commons Attribution License 4.0

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