African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12191

Full Length Research Paper

Antioxidant and antibacterial activities of Piliostigma reticulatum (DC.) Hochst extracts

Alexandre Zerbo1,  Jean Koudou2*, Noufou Ouédraogo1,  Rasmata Ouédraogo3and Innocent P. Guissou1
1Laboratoire de Pharmacologie-Toxicologie (UFR/SDS), Université de Ouagadougou, 03BP7021 Ouagadougou Burkina Faso. 2Laboratoire de chimie de substances naturelles, Faculté des Sciences, Université de Bangui, BP908 Bangui Centrafrique. 3Laboratoire de bactériologie-Virologie (UFR/SDS), Université de Ouagadougou, 03BP7021 Ouagadougou Burkina Faso.
Email: [email protected]

  •  Accepted: 07 August 2010
  •  Published: 31 August 2010

Abstract

The methanol and aqueous extracts of Piliostigma reticulatum barks were investigated for its antioxidant and antibacterial activities. The antioxidant test using 1,1-diphenyl-2-picrylhydrazyl (DPPH) method demonstrated important radical scavenging activity for the methanol extract with IC50 = 0,37 ± 0,04 µgmL-1.  The 2 extracts were then examined for antibacterial activity by using the broth micro dilution method. The extracts possessed the antibacterial effect against the almost germs tested; the aqueous extract exhibited a better activity than methanol extract. These results indicate that methanol and aqueous extracts of P. reticulatum could be used as a source of antioxidant and antibacterial ingredients in the food industry.

 

Key words: Piliostigma reticulatum, Ceasalpiniaceae, bark extracts, antioxidant, antibacterial.