African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12227

Full Length Research Paper

Investigation of carrier oil stabilized iron oxide nanoparticles and its antibacterial activity

K. L. Palanisamy*
  • K. L. Palanisamy*
  • Department of Physics, Sengunthar Engineering College, Tiruchengode, India
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V. Devabharathi
  • V. Devabharathi
  • Department of Physics, KSR Institute of Engineering and Technology, Tiruchengode, India
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N. Meenakshi Sundaram
  • N. Meenakshi Sundaram
  • Department of Biomedical Engineering, PSG College of Technology, Coimbatore, India
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  •  Received: 17 February 2014
  •  Accepted: 29 April 2014
  •  Published: 30 April 2014

Abstract

Iron oxide nanoparticles were synthesized by co-precipitation method. The polyunsaturated carrier oil (flaxseed oil) is used as a stabilizing agent for iron oxide nanoparticles. Kirby Bauer method was used to investigate the antibiotic sensitivity of carrier oil stabilized and uncoated SPIONs at 10 and 20 μg/L on Gram-positive bacterium Bacillus cereus (vegetative cell). The nanoparticles were characterized by X-ray diffraction method (XRD), Fourier transform infrared red (FTIR) analysis, particle size analyzer and Transmission Electron Microscopy. Structure of magnetite nanoparticles was confirmed by XRD analysis and the estimation of nanoparticle size was confirmed with TEM. The attachment of functional groups of oil was predicted using FTIR spectroscopy. This comparison study revealed that carrier oils stabilized iron oxide nanoparticles show more antibacterial activity than the bare iron oxide nanoparticles.

 

Key words: Iron oxide nanoparticles, flaxseed oil, Bacillus cereus