African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12504

Short Communication

Multi drug resistance and β-lactamase production by Klebsiella pneumoniae

Habeeb Khadri .C1, S. Surekha1, S. Lakshmi1 and G. Narasimha2*
1Department of Microbiology, Government Medical College, Anantapur, A. P. India 2Department of Microbiology, National PG College, Nandyal-518502 India.
Email: [email protected]

  •  Accepted: 22 June 2007
  •  Published: 31 August 2007

Abstract

The extended spectrum β-lactamase (ESBL) production and multidrug resistant ofKlebsiella pneumoniae in children below 5 years of ages are investigated. The K. pneumoniae strains isolated from patients suffering from intestinal and extra intestinal infection between the 0 - 5 year’s ages of children showed resistant to the three antibiotics (ceftazidime, cefotaxime, ceftriaxone), and coexist with non β-lactam resistance and ESBL production. All the strains were susceptibility to the antibiotic, imipenem. Out off 110 strains only 9 strains produced ESBL. The plasmid responsible for the antibiotic resistance and ESBL production can be transferred to recipientEscherichia coli strain.

 

Key words: Klebsiella pneumoniae, drug resistance, ESBL production.