African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12508

Full Length Research Paper

Serum total protein, albumin and globulin levels in Trypanosoma brucei-infected rabbits: Effect of orally administered Scoparia dulcis

N. E. J.  Orhue1*, E. A. C. NWANZE1 and A. OKAFOR2
1Department of Biochemistry, University of Benin, P.M.B 1154, Benin City, Nigeria. 2Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, 405 Hilgard Avenue, P.O. Box 951361, Los Angeles, CA. 900095-1361.
Email: [email protected]

  •  Accepted: 12 September 2005
  •  Published: 31 October 2005

Abstract

The effect of orally administered Scoparia dulcis on Trypanosoma brucei-induced changes in serum total protein, albumin and globulin were investigated in rabbits over a period of twenty eight days. Results obtained show that infection resulted in hyperproteinaemia, hyperglobulinaemia and hypoalbuminaemia. However these lesions were less severe (p<0.05) in the infected and treated group relative to their untreated counterparts. We speculate that the herb may be involved in modulating the severity of these trypanosome associated lesions by some yet undefined mechanisms

 

Key words: Trypanosoma brucei, total protein, albumin, globulin, Scoparia dulcis.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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