African Journal of

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12235

Full Length Research Paper

An approximate confidence interval for recombination fraction in genetic linkage analysis using a two stage Monte Carlo method Gibbs sampling

Gholamreza Jandaghi
Qom College, University of Tehran, Iran
Email: [email protected]

  •  Accepted: 03 January 2011
  •  Published: 14 February 2011



One of the important parameters in genetic linkage analysis is recombination fraction. In this paper, we proposed a two stage Markov Chain Monte Carlo (MCMC) method to calculate an approximate confidence interval (ACI) for the recombination fraction. We also presented a formula for calculation of simulation size namely: outer and inner Gibbs sample sizes.


Key words: Markov Chain Monte Carlo (MCMC), Gibbs sampler, approximate confidence interval, simulation size


MCMC, Markov Chain Monte Carlo; ACI, approximate confidence interval.

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