One of the important parameters in genetic linkage analysis is recombination fraction. In this paper, we proposed a two stage Markov Chain Monte Carlo (MCMC) method to calculate an approximate confidence interval (ACI) for the recombination fraction. We also presented a formula for calculation of simulation size namely: outer and inner Gibbs sample sizes.
Key words: Markov Chain Monte Carlo (MCMC), Gibbs sampler, approximate confidence interval, simulation size
MCMC, Markov Chain Monte Carlo; ACI, approximate confidence interval.
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