Medicinal plants contain natural bio-active constituents in various parts called photochemical that are of therapeutic importance. This research was undertaken to determine the phytochemical constituents and in-vitro antioxidant activities of ethyl acetate extract of Dryopteris dilatata leaves (DDL). Phytochemical analysis was determined on the plant samples following established protocols. The antioxidant property of Dryopteris dilatata leaves was evaluated using ferric reducing antioxidant power (FRAP), superoxide scavenging radical activity (SSRA) and hydroxyl radical activity (OH) assay. The results of the phytochemical analysis revealed the presence of the following phenols, terpenoid, alkaloids, flavonoids, tannins, cardiac glycosides and saponins, while steroids, carbohydrates, proteins, amino acids and phlobotannins were below detectable levels. DDL leaves produced significant (P<0.05) levels of ferric reducing antioxidant power (FRAP), superoxide scavenging radical activity (SSRA) and hydroxyl radical activity (OH) in a concentration dependent manner compared to the reference antioxidants, ascorbic acid and manitol; therefore, the extract could serve as free radical scavenger, acting as primary antioxidants. Based on the phytoconstituents and antioxidant activities, it could be concluded that D. dilatata could be of great value in the management of hyperglycemia, hyperlipidemia, and cancer, among other diseases that could be caused as a result of oxidative stress. This calls for further exploration of its bioactive compound.
Key words: Phytochemicals, Dryopteris dilatata, in-vitro antioxidant and, oxidative stress.
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