African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12463

Full Length Research Paper

Prevalence of drug resistance and genetic characterization of Mycobacterium tuberculosis complex strains from pulmonary tuberculosis patients co-infected with malaria at Jamot Hospital in Yaoundé

Tiani Lionel Ulrich
  • Tiani Lionel Ulrich
  • Department of Biochemistry, Faculty of Science, University of Yaoundé I, Cameroon.
  • Google Scholar
Ambassa Axel Cyriaque
  • Ambassa Axel Cyriaque
  • Department of Biochemistry, Faculty of Science, University of Yaoundé I, Cameroon.
  • Google Scholar
Assam Jean Paul Assam
  • Assam Jean Paul Assam
  • Laboratory for Tuberculosis Research and Pharmacology, Biotechnology Center, University of Yaoundé 1, Cameroon.
  • Google Scholar
Andoseh Genevieve
  • Andoseh Genevieve
  • Department of Biochemistry, Faculty of Science, University of Yaoundé I, Cameroon.
  • Google Scholar
Zeukeng Francis
  • Zeukeng Francis
  • Faculty of Sciences, University of Buea, Cameroun.
  • Google Scholar
Tchinda Cedric Fossi
  • Tchinda Cedric Fossi
  • Laboratory for Tuberculosis Research and Pharmacology, Biotechnology Center, University of Yaoundé 1, Cameroon.
  • Google Scholar
Tsasse Martine Augusta Flore
  • Tsasse Martine Augusta Flore
  • Laboratory for Tuberculosis Research and Pharmacology, Biotechnology Center, University of Yaoundé 1, Cameroon.
  • Google Scholar
Nkah Numfor Leonard
  • Nkah Numfor Leonard
  • Center for research on Medecinal plants and Traditional Medecine, Institute of Medical Research and medicinal plants studies (IMPM), Ministry of Scientific Research and innovation,Yaoundé, Cameroon.
  • Google Scholar
Gonsu Kamga Hortense
  • Gonsu Kamga Hortense
  • Cantam Project Manager/chef de projet, Fondation Congolaise pour la Recherche Médicale, Campus WHO/AFRO, Villa D6, Brazzaville, Rep Congo.
  • Google Scholar
Kouanfack Charles
  • Kouanfack Charles
  • Department of Microbiology and Infectious Diseases, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Cameroon.
  • Google Scholar
Pefura Yone Eric Walter
  • Pefura Yone Eric Walter
  • Hôpital du Jour, Central Hospital in Yaoundé, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, Yaoundé, Cameroon.
  • Google Scholar
Djuidje Ngounoue Marceline
  • Djuidje Ngounoue Marceline
  • Department of Biochemistry, Faculty of Science, University of Yaoundé I, Cameroon.
  • Google Scholar
Bigoga Jude Daiga
  • Bigoga Jude Daiga
  • Department of Biochemistry, Faculty of Science, University of Yaoundé I, Cameroon.
  • Google Scholar
Ntoumi Francine
  • Ntoumi Francine
  • Ethics Committee on Health Research in Central Africa (CERSAC), Cameroon.
  • Google Scholar
Beng Véronique Penlap
  • Beng Véronique Penlap
  • Department of Biochemistry, Faculty of Science, University of Yaoundé I, Cameroon.
  • Google Scholar


  •  Received: 04 July 2022
  •  Accepted: 26 August 2022
  •  Published: 30 September 2022

References

Anyangwe (2016). The effect of Malaria/HIV/TB triple infection on malaria parasitaemia, haemoglobin levels, CD4+ cell and acid fast bacilli counts in the south west region of Cameroon. Journal of Infectious Pulmonary Diseases 1(2):2470-3176.
Crossref

 

Assam-Assam JP, Beng VP, Cho-Ngwa F, Toukam M, Ngwe AAI, Kitavi M, Nzuki I, Nyonka JN, Tata E, Tedom JC, Skilton RA, Pelle R, Titanji VPK (2013). Mycobacterium tuberculosis is the causative agent of tuberculosis in the southern ecological zones of Cameroon, as shown by genetic analysis. BMC Infectious Diseases 13(1):1-12.
Crossref

 

Assam Assam JP, Feutsa TVT, Godwe C, Doungmo TS, Teuma DS, Penlap BV (2020). Genetic Diversity Using Spoligotyping Method in the Case of Pulmonary Tuberculosis in Certain Localities of West Region of Cameroon. Biochemistry and Molecular Biology 5(1):6-11.
Crossref

 

Assam Assam JP, Penlap VB, Cho-Ngwa F, Tedom JC, Ane-Anyangwe IN, Vencent T (2011). Mycobacterium tuberculosis complex drug resistance pattern and identification of species causing tuberculosis in the West and Centre regions of Cameroon. BMC Infectious Diseases 11(1):1-6.
Crossref

 

Bahbahani H, Al-Rashed M (2014). Tuberculosis and autoimmune hemolytic anemia: Case report and literature review. Journal of Applied Hematology 5(4):164-167.
Crossref

 

Baluku JB, Nassozi S, Gyagenda M, Namanda I, Andia-Biraro (2019). Prevalence of malaria and TB coinfection at a National Tuberculosis treatment centre in Uganda. Journal of Tropical Medicine.
Crossref

 

Bercion R, Kuaban C (1998). Resistance of Mycobacterium tuberculosis complex to the principal anti-bacillary drugs in Yaoundé, Cameroon. Bulletin de la Société de Pathologie Exotique 91(3):199-202.

 

Bourahima K, Somboro AM, Kone M, Holl JL, Baya B, Dabitao D, Diallo D, Diarra B, Kone A, Sarro YDS, Sanogo M (2022). Molecular epidemiology and genetic diversity of Mycobacterium tuberculosis complex in referral heath centers of Bamakon mali What is new? International Journal of Infectious Diseases 117:204-211.
Crossref

 

Canetti G, Rist N, Grosset J (1963). Mesure de la sensibilité du bacille tuberculeux aux drogues antibacillaires par la methode des proportions. Revue de Tuberculose et de Pneumologie 27:217-272.

 

Colombatti R, Penazzato M, Bassani F, Bassani F, Vieira CS, Lourenço AA, Vieira F, Teso S, Giaquinto C, Riccardi F (2011). Malaria prevention reduces in-hospital mortality among severely ill tuberculosis patients: a three-step intervention in Bissau, Guinea-Bissau. BMC Infectious Diseases 11(1):1-7.
Crossref

 

Coscolla M, Gagneux S Does M (2010). Tuberculosis genomic diversity explain disease diversity? Drug Discovery Today: Disease Mechanisms 7(1):e43-e59.
Crossref

 

Degommier J (1957). Nouvelle technique de coloration des bacilles tuberculeux pour la recherche en fluorescence. Annales de l'Institut Pasteur pp. 692-694.

 

Filliol I, Driscoll JR, Van Soolingen D, Kreis-wirth BN, Kremer K, Valetudie G, Anh DD, Barlow R, Banerjee D, Bifani PJ (2002). Global Distribution of My-cobacterium tuberculosis Spoligotypes. Emerging Infectious Diseases 8(11):1347-1349.
Crossref

 

Hermans PW, Messadi F, Guebrexabher H, van Soolingen D, de Haas PE, Heersma H, de Neeling H, Ayoub A, Portaels F, Frommel D (1995). Analysis of the population structure of Mycobacterium tuberculosis in Ethiopia, Tunisia and The Netherlands: usefulness of DNA typing for global tuberculosis epidemiology. Journal of Infectious Diseases 171(6):1504-1513.
Crossref

 

Huet M, Rist N, Boube G, Potier D (1971). Etude bactériologique de la tuberculose au Cameroun. Revue de la Tuberculose et Pneumologie 35:413-426.

 

Kamerbeek L, Schouls A, Kolk M, Van Agterveld D, Van Soolingen S, Kuijper A, Bunschoten H, Molhuizen R, Shaw M, Goyal M, Van Embden J (1997). Simultaneous Detection and Strain Differentiation of Mycobacterium tuberculosis for Diagnosis and Epidemiology. Journal of Clinical Microbiology 35(4):907-914.
Crossref

 

Kamgue L, Mouafo E, Kuaban C, Assam-Assam JP, Tedom JC, Niemann S (2013). Estimates of genetic variability of Mycobacterium tuberculosis complex and its association with drug resistance in Cameroon. Advances in Infectious Diseases 3:55-59.
Crossref

 

Koro Koro, Simo YK, Piam F, Kuaban C, Eyangoh S (2013). Population dynamics of tuberculous bacilli in Cameroon as assessed by spoligotyping. Journal of Clinical Microbiology 51(1):299-302.
Crossref

 

Kuaban C, Bercion R, Noeske J, Cunin P, Nkamsse P, Niobe SN (2000). Antituberculosis drug resistance in the West Province of Cameroon. International Journal of Tuberculosis and Lung Disease 4(4):356-360.

 

Kuaban C, Bercion R, Jifon G, Cunin P, Blackett KN (2000). Acquired antituberculosis drug resistance in Yaounde, Cameroon. International Journal of Tuberculosis and Lung Disease 4(5):427-432.

 

Kuaban C, Toukam LDI, Sander M (2020). Treatment outcomes and factors associated with unfavorable outcome among previously treated tuberculosis patients with isoniazid resistance in four regions of Cameroon. Pan African Medical Journal 37(45).
Crossref

 

Ledru S, Cauchoix B, Yameogo M, Zoubga A, Lamande-Chiron J, Portaels F, Chiron JP (1996). Impact of short-course therapy on tuberculosis drug resistance in South-West Burkina Faso. Tubercle and Lung Disease 77(5):429-436.
Crossref

 

Molina-Moya B, Lacoma A, Prat C, Diaz J, Dudnyk A, Haba L, Maldonado J, Samper S, Ruiz-Manzano J, Ausina V, Dominguez J (2015). AID TB resistance line probe assay for rapid detection of resistant Mycobacterium tuberculosis in clinical samples. Journal of Infection 70(4):400-408.
Crossref

 

Molina-Moya B, Saddiq TA, Madukaji LI, Gomgnimbou MK, Lizania S, Meissiner GF, Harrison MG, Kacimi S, Russell D, Bimba JS, Lawson L, Sola C, Cuevas LE, Dominguez J (2018). Genetic characterization of Mycobacterium tuberculosis complex isolates circulating in Abuja, Nigeria. Infection and Drug Resistance 11:1617-1625.
Crossref

 

Murphy JR (1980). Host defenses in murine malaria: Immunological characteristics of a protracted state of immunity to Plasodium yoelii. Infection and Immunity 27(1):68-74.
Crossref

 

National Malaria Control Strategic Plan in Cameroon (NMCSP) 2019-2023.

View

 

NTCP (2019). Epidemiological situation of tuberculosis in Cameroon.

View

 

Niobe-Eyangoh S, Kuaban C, Sorlin P, Cunin P, Thonnon J, Sola C, Rastogi N, Vincent V, Cristina Gutierrez M (2003). Genetic Biodiversity of Mycobacterium tuberculosis complex strains from patients with pulmonary tuberculosis in Cameroon. Journal of Clinical Microbiology 41(6):2547-2553.
Crossref

 

Onana AT, Koro KF, Mokam FB, Ateugieu GR, Tchamba M, Somo MR, Ngono NRA, Etoa FX (2018). Is Mycobacterium africanum Constitute a Public Health Problem in Douala: The Most Cosmopolite Town of Cameroon. Journal of Molecular Microbiology 2(1):4.

 

Otokunefor K, Otokunefor TV, Omakwele G (2018). Multi-drug resistant Mycobacterium tuberculosis in Port Harcourt, Nigeria. African Journal of Laboratory Medicine 7(2):1-4.
Crossref

 

Page KR, Jedlicka AE, Fakheri B (2005). Mycobacterium-induced Potentiation of type 1 immune response and protection against Malaria. Are Host specific. Infection and immunity 73(12):8369-8380.
Crossref

 

Pokam TB, Yeboah-Manu PM, Teyim PW, Guemdjom (2020). A pilot study on the genetic diversity of Mycobacterium tuberculosis complex strains from tuberculosis patients in the Littoral region of Cameroon. Journal of Clinical Tuberculosis and Other Mycobacterial Diseases 21:100182.
Crossref

 

Quakyi IA, Leke RGF, Befidi-Mengue R, Tsafack M (2000). The epidemiology of Plasmodium falciparum malaria in two Cameroonian villages: Simbok and Etoa. American Journal of Tropical Medecine and Hygiene 63(5-6):222-230.
Crossref

 

Range N, Magnussen PA, Mugomela A (2007). HIV and parasitic co-infections in tuberculosis patients: Across-sectional study in Mwanza, Tanzania. Annals of Tropical Medicine & Parasitology 101(4):343-351.
Crossref

 

Seyoum B, Demissie M, Worku A, Bekele S, Aseffa A (2014). Prevalence and Drug Resistance Patterns of Mycobacterium tuberculosis among New Smear Positive Pulmonary Tuberculosis Patients in Eastern Ethiopia. Tuberculosis Research and Treatment
Crossref

 

Sidze LK, Mouafo Tekwu E, Kuaban C, Assam Assam JP, Tedom JC, Eyangoh S, Fouda FX, Nolna D, Ntoumi F, Frank M, Penlap BNV (2014). Strong Decrease in Streptomycin-Resistance and Absence of XDR 12Years after the Reorganization of the National Tuberculosis Control Program in the Central Region of Cameroon. PLoS ONE 9(6):e98374.
Crossref

 

Simon F, Menard M, Le Mao G, Albert JP (1989). Action antituberculeuse au Burkina faso. L'experience du service de Pneumo-phtisiologie de l'Hôpital National Sanon Souro de Bobo-Dioulasso. Paris, France: Societe? Sante? Industrie Service.

 

Soini H, Musser JM (2001). Molecular diagnosis of mycobacteria. Clinical Chemistry 47(5):809-814.
Crossref

 

Tchatchouang S, Anne L, Wetewale T, Makafé G, Kamgue SL, Tekou ME, Tedom JC, Assam Assam JP, Penlap BV (2015). Mycobacterium tuberculosis complex identification by polymerase chain reaction from positive culture in patients from Jamot and Mbalmayo district hospitals. African Journal of Biotechnology 14(11):971-978.

 

Titanji VPK, Assam JPA (2016). Drug Sensitivity and Molecular Diversity of M. tuberculosis in Cameroon: A Meta-analysis. Journal of Vascular Medicine and Surgery 4:3.

 

Valencia S, Respeito D, Blanco S, Ribeiro RM, Lopez-Varela E, Sequera VG, Saavedra B, Mambuque E, Gomez-Morillo M, Bulo H, Cobelens F, Macete E, Alonso PL, Caminero JA, Garc?a-Basteiro AL (2017). Tuberculosis drug resistance in Southern Mozambique: results of a population-level survey in the district of Manhiça. International Journal of Tuberculosis and Lung Disease 21(4):446-451.
Crossref

 

Vekemans M, Cartoux M, Diagbouga S, Dembele M, Kone B, Delafosse A, Dera A, Van De Perre P (1999). Potential source of human exposure to Mycobacterium bovis in Burkina Faso, in the context of the HIV epidemic. Clinical Microbiology and Infection 5(10):617-21.
Crossref

 

World Health Organization (WHO) (2016). Treatment Guidelines for Drug-Resistant Tuberculosis. (WHO/HTM/TB/2016.04). Geneva, Switzerland.

 

World Health Organization (WHO) (2017). Global Tuberculosis Report 2017. Geneva; 2017. (WHO/HTM/2017/23)

 

World Health Organization (WHO) (2019). Global Tuberculosis Report 2019, World Health Organization, Geneva, Switzerland, 2019

 

World Health Organization (WHO) (2019a). World malaria report 2019: briefing:

View

 

World Health Organization (WHO) (2019b). Global tuberculosis report 2019. Geneva (Switzerland).

 

Warren R, de Kock M, Engelke E, Myburgh R, Gey van Pittius N, Victor T, van Helden P (2006). Safe Mycobacterium tuberculosis DNA extraction method that does not compromise integrity. Journal of Clinical Microbiology 44(1):254-256.
Crossref