African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12209

Full Length Research Paper

Antibiotic susceptibility pattern of Pseudomonas aeruginosa expressing blaGES and blaPER genes in two different hospitals

Omar B. Ahmed
  • Omar B. Ahmed
  • Department of Environmental and Health Research, The Custodian of the Two Holy Mosques Institute for Hajj and Umrah, Umm Al-Qura University, Makkah, Saudi Arabia.
  • Google Scholar
Atif H. Asghar
  • Atif H. Asghar
  • Department of Environmental and Health Research, The Custodian of the Two Holy Mosques Institute for Hajj and Umrah, Umm Al-Qura University, Makkah, Saudi Arabia.
  • Google Scholar


  •  Received: 07 April 2017
  •  Accepted: 16 May 2017
  •  Published: 24 May 2017

References

Aggarwal R, Chaudhary U, Bala K (2008). Detection of extended-spectrum β-lactamase in Pseudomonas aeruginosa. Indian J. Pathol. Microbiol. 51(2):222-224.
Crossref

 

Ahmed OB, Asghar AH, Elhassan MM (2014) Comparison of three DNA extraction methods for polymerase chain reaction (PCR) analysis of bacterial genomic DNA. Afr. J. Microbiol. Res 8:598-602.
Crossref

 
 

Arya M, Arya P, Biswas D, Prasad R (2005). The antimicrobial susceptibility pattern of the bacterial isolates from post-operative wound infections. Indian J. Pathol. Microbiol. 48(2):266-269.

 
 

Azab M, Shehata A, Mohamed M (2015). OXA- 10 and GES-1 Extended-spectrum β-lactamases Play A Major Role in Causing Antibiotic Resistance of Pseudomonas aeruginosa Isolated from Nosocomial Infections in Ismailia, Egypt. Egypt. J. Med. Microbiol. 24(4):81-88.
Crossref

 
 

Bashir D, Thokar MA, Fomda BA, Bash G, Zahoor D, Ahmad SA, Toboli AS (2011). Detection of metallobeta- lactamases (MBL) producing Pseudomonas aeruginosa at a tertiary care hospital in Kashmir. Afr. J. Microbiol. Res. 5:164-172.

 
 

Bavasheh N, Karmostaji A (2017). Antibiotic Resistance Pattern and Evaluation of blaOXA-10, blaPER-1, blaVEB, blaSHV Genes in Clinical Isolates of Pseudomonas aeruginosa Isolated from Hospital in South of Iran in 2014-2015. Infect. Epidemiol. Med. 3(1):1-5.
Crossref

 
 

Bodey GP, Bolivar R, Fainstein V, Jadeja L (1983). Infections caused by Pseudomonas aeruginosa. Rev. Infect. Dis. 5:279-313.
Crossref

 
 

Castanheira M, Mendes RE, Walsh TR (2004). Emergence of the extended-spectrum beta-lactamase GES-1 in a Pseudomonas aeruginosa strain from Brazil: Report from the SENTRY Antimicrobial Surveillance Program. Antimicrob. Agents Chemother. 48:2344-2345.
Crossref

 
 

Celenza G, Pellegrini C, Caccamo M, Segatore B, Amicosante G, Perilli M (2006). Spread of bla(CTX-M-type) and bla(PER-2) beta-lactamase genes in clinical isolates from Bolivian hospitals. J. Antimicrob. Chemother. 57(5):975-978.
Crossref

 
 

CLSI-Clinical and Laboratory Standards Institute (2012). NCCLS. Performance Standards for Antimicrobial Susceptibility Testing; 15th information supplement. CLSI document M100-S15. Clinical and Laboratory Standards Institute, Wayne, PA.

 
 

Easwaran S, Yerat RC, Ramaswamy R (2016). A study on detection of extended-spectrum beta-lactamases (ESBLs) and comparison of various phenotypic methods of AmpC detection in Pseudomonas aeruginosa from various clinical isolates in a tertiary care teaching hospital. Muller J. Med. Sci. Res. 7(1):35-39.
Crossref

 
 

Empel J, Filczak K, Mro’wka A, Hryniewicz W, Livermore DM, Gniadkowski M (2007). Outbreak of Pseudomonas aeruginosa Infections with PER-1 Extended-Spectrum _-Lactamase in Warsaw, Poland: Further Evidence for an International Clonal Complex. J. Clin. Microbiol. 45(9):2829-2834.
Crossref

 
 

Er H, Altindis M, Asik G, Demir C (2015). Molecular epidemiology of beta-lactamases in ceftazidime resistant Pseudomonas aeruginosa isolates. Mikrobiyol. Bul. 49(2):156-165.
Crossref

 
 

Falagas ME, Kasiakou SK (2005). Colistin: the revival of polymyxins for the management of multidrug-resistant gram-negative bacterial infections. Clin. Infect. Dis. 40:1333-1341.
Crossref

 
 

Frase H, Smith CA, Toth M, Champion MM, Mobashery S, Vakulenko SB (2011). Identification of products of inhibition of GES-2 beta-lactamase by tazobactam by x-ray crystallography and spectrometry. J. Biol. Chem. 286(16):14396-14409.
Crossref

 
 

Garza-Ramos U, Barrios H, Reyna-Flores F, Tamayo-Legorreta E, Catalan-Najera JC, MorfinOtero R, Rodríguez-Noriega E, Volkow P, Cornejo-Juarez P, González A, Gaytan-Martinez J, Del Rocío Gónzalez-Martínez M, Vazquez-Farias M, Silva-Sanchez J (2015). Widespread of ESBL- and carbapenemase GES-type genes on carbapenemresistant Pseudomonas aeruginosa clinical isolates: a multicenter study in Mexican hospitals. Diagn. Microbiol. Infect. Dis. 81(2):135-137.
Crossref

 
 

Gul AA, Ali L, Rahim E, Ahmed S (2007). Chronic suppurative otitis media; frequency of Pseudomonas aeruginosa in patients and its sensitivity to various antibiotics. Prof. Med J. 14:411-415.

 
 

Haider M, Rizvi M, Fatima N, Shukla I, Malik A (2014). Necessity of detection of extended spectrum beta-lactamase, AmpC and metallo-beta-lactamases in gram-negative bacteria isolated from clinical specimens. Muller J. Med. Sci. Res. 5:23-28.
Crossref

 
 

Kontopoulou K, Protonotariou E, Vasilakos K, Kriti M, Koteli A, Antoniadou E, Sofianou D (2010) Hospital outbreak caused by Klebsiella pneumoniae producing KPC-2 β-lactamase resistant to colistin. J. Hosp. Infect. 76:70-73.
Crossref

 
 

Lee S, Park YJ, Kim M, Lee HK, Han K, Kang CS, Kang MW (2005). Prevalence of Ambler class A and D beta-lactamases among clinical isolates of Pseudomonas aeruginosa in Korea. J. Antimicrob. Chemother. 56(1):122-127.
Crossref

 
 

Libisch B, Poirel L, Lepsanovic Z, Mirovic V, Balogh B, Paszti J, Hunyadi Z, Ak AD, Ak MF, Nordmann P (2008). Identi¢cation of PER-1extended-spectrumb-lactamase producing Pseudomonas aeruginosa clinical isolates oftheinternational clonal complex CC11from Hungary and Serbia. FEMS Immunol. Med. Microbiol. 54:330-338.
Crossref

 
 

Linden PK, Kusne S, Coley K, Fontes P, Kramer DJ, Paterson D (2003). Use of parenteral colistin for the treatment of serious infection due to antimicrobial-resistant Pseudomonas aeruginosa. Clin. Infect. Dis. 37:e154-e160.
Crossref

 
 

Lister PD, Wolter DJ, Hanson ND (2009). Antibacterial-Resistant Pseudomonas aeruginosa: Clinical Impact and Complex Regulation of Chromosomally Encoded Resistance Mechanisms. Clin. Microbiol. Rev. 22(4):582-610.
Crossref

 
 

Livermore DM (1995). Beta-lactamases in laboratory and clinical resistance. Clin. Microbiol. Rev. 8:557-584.

 
 

Livermore DM (2002). Multiple mechanisms of antimicrobial resistance in Pseudomonas aeruginosa: our worst nightmare? Clin. Infect. Dis.
Crossref

 
 

Luzzaro F, Mantengoli E, Perilli M, Lombardi G, Orlandi V, Orsatti A, Amicosante G, Rossolini GM, Toniolo A (2001). Dynamics of a nosocomial outbreak of multidrug-resistant Pseudomonas aeruginosa producing the PER-1 extended-spectrum beta-lactamase. J Clin Microbiol. 39(5):1865-1870.
Crossref

 
 

Mirsalehian A, Feizabadi M, Nakhjavani FA, Jabalameli F, Goli H, Kalantari N (2010). Detection of VEB-1, OXA-10 and PER-1 genotypes in extended-spectrum β-lactamase-producing Pseudomonas aeruginosa strains isolated from burn patients. Burns 36(1):70-74,
Crossref

 
 

Obritsch MD, Fish DN, Maclaren R, Jung R (2004). The national surveillance of antimicrobial resistance in the Pseudomonas aeruginosa isolates obtained from intensive care unit patients from 1993 to 2002. Antimicrob. Agents Chemother. 48:4606-4610.
Crossref

 
 

Olowe OA, Adefioye S (2014). Understanding extended spectrum betalactamases in clinical settings. Review update. Int. J. Med. Appl. Sci. 3(3):51-61.

 
 

Picao RC, Poirel L, Gales AC, Nordmann P (2009). Diversity of beta-lactamases produced by ceftazidime-resistant pseudomonas aeruginosa isolates causing bloodstream infections in Brazil. Antimicrob. Agents Chemother. 53:3908-3913.
Crossref

 
 

Poirel L, Thomas IL, Naas T, Karim A, Nordmann P (2000). Biochemical sequence analyses of GES-1, a novel class A extended-spectrum betalactamase, and the class 1 integron In52 from Klebsiella pneumoniae. Antimicrob. Agents Chemother. 44:622-632.
Crossref

 
 

Poirel L, Weldhagen GF, Naas T, Champs C, Dove MG, Nordmann P (2001). GES-2, a class A β- lactamase from Pseudomonas aeruginosa with increased hydrolysis of imipenem. Antimicrob. Agents Chemother. 45(1):2598-2603.
Crossref

 
 

Shacheraghi F, Shakibaie MR, Noveiri H (2010). Molecular Identification of ESBL Genes blaGES-1, blaVEB-1, blaCTX-M blaOXA-1, blaOXA-4, blaOXA-10 and blaPER-1 in Pseudomonas aeruginosa Strains Isolated from Burn Patients by PCR, RFLP and Sequencing Techniques. Int. Sch. Sci. Res. Innov. 4(1):1009-1013.

 
 

Shaikh S, Fatima J, Shakil S, Mohd S. Rizvi D, Kamal M A (2015). Prevalence of multidrug resistant and extended spectrum beta-lactamase producing Pseudomonas aeruginosa in a tertiary care hospital. Saudi J. Biol. Sci. 22:62-64.
Crossref

 
 

Sidjabat HE, Paterson D L., Adams-Haduch J M, Ewan L, Pasculle AW, Muto CA, Tian G-B, Doi Y (2009). Molecular Epidemiology of CTX-M-Producing Escherichia coli Isolates at a Tertiary Medical Center in Western Pennsylvania. Antimicrob. Agents Chemother. 53(11):4733-4739.
Crossref

 
 

Tavajjohi Z, Moniri R, Zarrabi M (2013). Detection of GES-2, a Class A β-Lactamase Produced by Pseudomonas aeruginosa in a Teaching Hospital in Iran. Jundishapur J. Microbiol. 6(10):e8166.
Crossref

 
 

Tawfik AF, Shibl AM, Aljohi MA, Altammami MA, Al-Agamy MH (2012). Distribution of Ambler class A, B and D beta-lactamases among Pseudomonas aeruginosa isolates. Burns 38(6):855-860.
Crossref

 
 

Umadevi S, Joseph NM, Kumari K, Easow JM, Kumar S, Stephen S, Srirangaraj S, Raj S (2011). Detection of extended spectrum beta lactamases, ampc beta lactamases and Metallobetalactamases in clinical isolates of ceftazidime resistant Pseudomonas Aeruginosa. Braz. J. Microbiol. 42:1284-1288.
Crossref

 
 

Vahaboglu H, Oztürk R, Aygün G, Co┼čkunkan F, Yaman A, Kaygusuz A, Leblebicioglu H, Balik I, Aydin K, Otkun M (1997). Widespread detection of PER-1type extended-spectrum β-lactamases among nosocomial Acinetobacter and Pseudomonas aeruginosa isolates in Turkey: a nationwide multicenter study. Antimicrob. Agents Chemother. 41:2265-2269.

 
 

Weldhagen GF, Poirel L, Nordmann P (2003). Ambler class A extendedspectrum beta-lactamases in Pseudomonas aeruginosa: novel developments and clinical impact. Antimicrob. Agents Chemother. 47(8):2385-2392.
Crossref

 
 

Yetkin G, Otlu B, Cicek A, Kuzucu C, Durmaz R (2006). Clinical, microbiologic, and epidemiologic characteristics of Pseudomonas aeruginosa infections in a university hospital, Malatya, Turkey. Am. J. Infect. Control 34:188-192.
Crossref