African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12218

Full Length Research Paper

Overexpression of key enzymes of the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway for improving squalene production in Escherichia coli

Haiyuan Liu
  • Haiyuan Liu
  • China State Institute of Pharmaceutical Industry, Zhangjiang Insitute, Shanghai 201203, China.
  • Google Scholar
Shu Han
  • Shu Han
  • China State Institute of Pharmaceutical Industry, Zhangjiang Insitute, Shanghai 201203, China.
  • Google Scholar
Liping Xie
  • Liping Xie
  • China State Institute of Pharmaceutical Industry, Zhangjiang Insitute, Shanghai 201203, China.
  • Google Scholar
Jie Pan
  • Jie Pan
  • China State Institute of Pharmaceutical Industry, Zhangjiang Insitute, Shanghai 201203, China.
  • Google Scholar
Wei Zhang
  • Wei Zhang
  • China State Institute of Pharmaceutical Industry, Zhangjiang Insitute, Shanghai 201203, China.
  • Google Scholar
Guihua Gong
  • Guihua Gong
  • China State Institute of Pharmaceutical Industry, Zhangjiang Insitute, Shanghai 201203, China.
  • Google Scholar
Youjia Hu
  • Youjia Hu
  • China State Institute of Pharmaceutical Industry, Zhangjiang Insitute, Shanghai 201203, China.
  • Google Scholar


  •  Received: 07 September 2017
  •  Accepted: 16 November 2017
  •  Published: 13 December 2017

How to cite this article

APA /
Liu, H., Han, S., Xie, L., Pan, J., Zhang, W., Gong, G., & Hu, Y. (2017). Overexpression of key enzymes of the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway for improving squalene production in Escherichia coli. African Journal of Biotechnology , 16(50), 2307-2316.
Chicago /
Haiyuan Liu, Shu Han, Liping Xie, Jie Pan, Wei Zhang, Guihua Gong and Youjia Hu. "Overexpression of key enzymes of the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway for improving squalene production in Escherichia coli." African Journal of Biotechnology 16, no. 50 (2017): 2307-2316.
MLA /
Haiyuan Liu, et al. "Overexpression of key enzymes of the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway for improving squalene production in Escherichia coli." African Journal of Biotechnology 16.50 (2017): 2307-2316.