African Journal of
Biochemistry Research

  • Abbreviation: Afr. J. Biochem. Res.
  • Language: English
  • ISSN: 1996-0778
  • DOI: 10.5897/AJBR
  • Start Year: 2007
  • Published Articles: 401

Full Length Research Paper

Correlation between glycated hemoglobin and venous blood sugar in diabetic patients monitored in Abidjan

MONDE Aké Absalome
  • MONDE Aké Absalome
  • Félix HOUPHOUËT-BOIGNY University, Cocody, Abidjan, Côte d’Ivoire.
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CAMARA-CISSE Massara
  • CAMARA-CISSE Massara
  • Biochemistry Laboratory, Abidjan Medical School, Félix HOUPHOUËT BOIGNY University, Côte D'ivoire.
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KOFFI Konan Gervais
  • KOFFI Konan Gervais
  • Biochemistry Laboratory, Abidjan Medical School, Félix HOUPHOUËT BOIGNY University, Côte D'ivoire.
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DIALLO Issiagha
  • DIALLO Issiagha
  • Biochemistry Laboratory, University Hospital Center of Treichville, Côte D'ivoire.
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AKE AKE Alexandre
  • AKE AKE Alexandre
  • Laboratory of Medical Biochemistry, Faculty of Medical Sciences, Félix HOUPHOUËT-BOIGNY University, Côte D'ivoire.
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YAPO-AKE Bénédicte
  • YAPO-AKE Bénédicte
  • Laboratory of Medical Biochemistry, Faculty of Medical Sciences, Félix HOUPHOUËT-BOIGNY University, Côte D'ivoire.
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ECRABEY Yann Christian
  • ECRABEY Yann Christian
  • Biochemistry Laboratory, University Hospital Center of Treichville, Côte D'ivoire.
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KOUAKOU Francisk
  • KOUAKOU Francisk
  • Biochemistry Laboratory, University Hospital Center of Treichville, Côte D'ivoire.
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BENE YAO Roger Espérance
  • BENE YAO Roger Espérance
  • Laboratory of Medical Biochemistry, Faculty of Medical Sciences, Félix HOUPHOUËT-BOIGNY University, Côte D'ivoire.
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TIAHOU Georges
  • TIAHOU Georges
  • Laboratory of Medical Biochemistry, Faculty of Medical Sciences, Alassane OUATTARA University, Bouaké, Côte D'ivoire.
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  •  Received: 23 August 2020
  •  Accepted: 02 October 2020
  •  Published: 31 October 2020

Abstract

The aim of this study was to determine the correlation between glycated hemoglobin and blood sugar levels in diabetic subjects carried out in Abidjan. This cross-sectional study included 100 patients with diabetes monitored, for three months, for whom glycated blood glucose and hemoglobin were performed, this after informed consent of the patients. Pearson and Spearman correlation tests were used, at the 5% threshold. The patients with normal HbA1C and normal blood glucose accounted for 55.34 and 32%, respectively. A sedentary lifestyle and body mass index > 25 kg/m² were associated with a significant increase in the risk of increased blood glucose and HbA1C. The presence of a complication was associated with a 3.06-fold higher risk of high glycated hemoglobin (p= 0.0073), while blood glucose was not significantly associated with the onset of complications. Glycated hemoglobin was significantly correlated with blood glucose with a correlation coefficient of 0.4412 (p 0.0001). In multivariate analysis, hyperglycemia was significantly associated with alcohol consumption and non-compliance with antidiabetic treatment. Poor compliance was significantly associated with increased glycated hemoglobin (>7%) and tobacco consumption. The glycated hemoglobin was highly correlated with blood sugar, and was found to be a better predictor of diabetes complications than glycemia.

 

Key words: Diabetes mellitus, glycated hemoglobin, blood sugar, Abidjan, Côte d’Ivoire.