Serum protein fractions evaluation in blood donors in Ouagadougou, Burkina Faso
Article in Press
Some endemic conditions lead to a disturbance of the serum protein fractions, an indicator of infection and inflammatory syndrome. Thus, in order to contribute to the assessment of the state of health of the blood donor at the Regional Blood Transfusion Center of Ouagadougou (CRTSO), we undertook to evaluate serum protein fractions in blood donors. The study population consisted of voluntary donors declared fit to donate...
Comparison of DNA Purity Between Males and Females in The Volta Region of Ghana
Article in Press
Buccal swab samples have gained popularity in genetic research due to their speed, painlessness, and low cost. This study aimed at comparing DNA concentrations obtained from buccal swab samples between males and females in the Volta Region of Ghana. To extract DNA for analysis, buccal swab samples were taken from a cohort of 125 males and 115 females in this investigation. A nanodrop spectrophotometer was used to detect...
Article in Press
Profile of Biochemical Markers of Malnutrition and Iron Deficiency in Chronic Kidney Disease Patients Hemodialyzed at Souro Sanou University Hospital Undernutrition and iron deficiency in hemodialysis patients are associated with a high risk of mortality. The aim of this study was to evaluate the profile of biochemical markers of protein undernutrition and iron deficiency in hemodialysis patients. This was a descriptive...
Insecticides Resistance in Anopheles Mosquitoes from Katsina State Nigeria
Article in Press
It has been previously reported that insecticide resistance among the vectors of malaria and lymphatic filariasis (LF) exist in the African continent which could unintentionally affect different species of Anopheles mosquitoes found in Katsina State Nigeria and its insecticides resistance. This study's objectives were to identify the Anopheles mosquito species that can be found in Katsina State Nigeria and its profile...
Antioxidation and Cytoprotection Mechanisms of Ficus asperifolia in Diabetic Rats
Article in Press
Background: The current study tested the hypothesis that Ficus asperifolia from West Africa could be used as an anti-diabetic plant through the antioxidation and cytoprotection mechanism using a diabetic murine model. Methods: An unbiased metabolomics approach applied include: vitamins, mineral contents, ferric reducing-antioxidant power (FRAP), and thiobarbituric acid reactive substance (TBARS) were analyzed...
Article in Press
Obesity is fast becoming an endemic disease associated with various other complications due to nutritional imbalance. The study was set up to assess the plasma levels of glucose, cholesterol and selected electrolytes in obese and normo-weight individuals. The weights and heights of healthy individuals were measured and the body mass indices (BMI) calculated in kg/m2. Individuals with BMI> 30 were considered obese while...
Effect of Dietary Administration of Bixa orellana Seeds on Liver and Kidney Parameters in Rats
Article in Press
Bixa orellana seed powder is used as a natural food colorant in many locally prepared foods of northern Nigeria. This study was conducted to determine the effect of dietary exposure to B. orellana whole seeds on liver and kidney parameters in male rats. Twelve male Wistar rats (4 rats/group) were fed diet mixed with B. orellana seed powder at 0, 0.5 and 5% for four weeks. Animal body weight, food consumption, absolute...
Article in Press
Palm oil has long been incriminated in obesity, and this obesity would be responsible for the development of cardiac fibrosis, several authors have evoked the role of free radicals in the pathophysiological mechanism of the fibrotic response linked to obesity; The aim of this study was therefore to evaluate the profile of NOX2 in the development of cardiac fibrosis in rats subjected to a diet rich in the fat of several...
Dynamics of Ascaridigalli infection and serum retinol level following supplementation with Vitamin A
Article in Press
The present study was conducted to assess the effect of Ascaridia galli infection on vitamin A supplementation and serum retinol concentrations. These were assessed in 100 eight weeks ISA brown chickens experimentally infected with A. galli. The chickens were divided into four equal groups (G1, G2, G3 and G4) of ten chickens (n=10). The chickens were experimentally infected with 350 eggs of A. galli and daily supplemented...
Article in Press
Glutathione transferase is a mutigene family of enzymes catalyzing the conjugation of glutathione with a large variety of xenobiotics. Glutathione transferase acts on different substrates and can protect insects against various plant allelochemicals and chemical insecticides. An investigation of glutathione transferase in the gut of Palm weevil (Rhynchophorus phoenicis) larva, a lethal pest of palm was carried out. This...
Article in Press
The present study examined the roles of ascorbic acid (AA) on hematological indices, hepatic function and lipid profile, and liver histology in rats co-treated with Atrazine (ATZ) and sodium nitrate (NaNO3). The hematological indices, liver function tests, lipid profile, and liver histology were performed using standard protocols. The [ATZ + NaNO3] significantly (p < 0.05) reduced the levels of hemoglobin, red blood cells,...
Tamoxifen treatment improves serum lipid profile with possible cardio-protective effect.
Article in Press
Breast cancer is the most widely recognized cancer in women worldwide and it is the main source of cancer demise in less created nations. Dyslipidemia in breast cancer patients has been considered as a hazard factor for cardiovascular diseases. Tamoxifen is basically hostile to estrogenic and its estrogenic action is fundamentally liable for the adjustments in lipid parameters. Investigation of lipid profiles among breast...
IN VITRO ANTIOXIDANT ACTIVITIES OF Carissa edulis VAHL AND Caesalpinia volkensii HARMS EXTRACTS
Article in Press
Carissa edulis and Caesalpinia volkensii have been used through ages by herbalists in many parts of the world to treat various ailments. Although these medicinal plants have been widely used traditionally in treating diseases associated with oxidative stress, there is limited literature to validate their use. This study therefore, sought to determine the ethnobotanical efficacy of the plants as alternatives in the...
Article in Press
The study was focused on the quantitative determination of some selected essential and heavy metals in avocado, banana and mango samples with their respective supported soil samples collected from 8 kebeles of Yeki woreda. The investigated metals were Ca, Cd, Cr, Cu, Ni, Pb and Zn. Acid digestion was used for sample digestion. Flame atomic absorption spectrometer (FAAS) was used to determine the concentration of metals....
Article in Press
The global malaria control and elimination strategies are constrained by the emergence and spread of multi-drug resistant Plasmodium falciparum, Plasmodium vivax and Plasmodium malariae strains to most antimalarials. Currently, studies reveal rising incidences of reduced parasite susceptibility to the artemisinin-based combination therapies (ACTs), the recommended first-line treatment regimen for uncomplicated P....
Acute oral toxicity study of Acacia nilotica bark of aqueous methanolic extract in albino mice
Article in Press
The beneficial use of medicinal plant among rural communities has been reported over century’s medicinal properties and toxicity of the plant varies depending on the part of the plant taken like leaves, roots, stem and bark as well as geographical distribution, climate change and nature of the soil. This study aimed to assess the acute toxicity of Tanzania Acacia nilotica extracts in mice. The information generated is...
Article in Press
Lannea acida plants belong to the family Anacardiaceae. It has been used locally to treat and manage diseases that are contagious. Due to the recent increase in the resistance of malaria parasite to synthetic drugs the search for alternative treatment approach from plant sources is in urgent dimension. The antiplasmodial activity of mice was investigated with L. acida bark extracts. The study of the acute toxicity of the...
Article in Press
This study evaluated the effect of methanol extract of mango (Magnifera indica) seed flour on acetaminophen-induced cardiotoxicity in albino rats. Twenty four (24) male and female albino rats were divided into 6 groups consisted of 4 rats: a)Group1: Control group (no induction and treated with distilled water only);b) Group 2 (acetaminophen-induced and untreated); c) Group 3 (acetaminophen-induced and pre-treated with...
Article in Press
The objective of our study was to develop 96 well-microtiter plate 2, 2’-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) based decolorization assay method for analysis of large number of samples in a single run for the screening of antioxidant activity of various extracts such as food extracts, plasma antioxidants and synthetic antioxidants and optimization was carried out for parameters like concentration,...
Article in Press
This study focused on the integrity retention profile of hematological disorder indices on exposure to ethanol extract of Corchorus olitorus leaf. Seventy two apparently healthy rats were obtained from the animal farm of the Department of Zoology and Environmental Biology University of Nigeria, Nsukka and used for this study. These indices include assessed were Red blood cell distribution width standard deviation, Red...
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