African Journal of
Biochemistry Research

  • Abbreviation: Afr. J. Biochem. Res.
  • Language: English
  • ISSN: 1996-0778
  • DOI: 10.5897/AJBR
  • Start Year: 2007
  • Published Articles: 421

Full Length Research Paper

Statistical optimization of L–glutaminase production by Trichoderma species under solid state fermentation using African locust beans as substrate

Musa Olatunji Olarewaju
  • Musa Olatunji Olarewaju
  • Department of Biochemistry, Faculty of Life Sciences, Ahmadu Bello University, Zaria, Nigeria.
  • Google Scholar
Humphrey Chukwuemeka Nzelibe
  • Humphrey Chukwuemeka Nzelibe
  • Department of Biochemistry, Faculty of Life Sciences, Ahmadu Bello University, Zaria, Nigeria.
  • Google Scholar

  •  Received: 24 January 2019
  •  Accepted: 20 February 2019
  •  Published: 31 July 2019


Abdallah NA, Amer SK, Habeeb MK (2013). Production, purification and characterization of L-glutaminase enzyme from Streptomyces avermitilis. African Journal of Microbiology Research 7(14):1184-1190.


Ahmed AM, El-Katatny MH (2007). Entomopathogenic fungi as biopesticides against the Egyptian cotton leaf worm, Spodopteralittoralis: between biocontrol-promise and immune-limitation. Journal of the Egyptian Society of Toxicology 37:39-51.


Binod P, Sindhu R, Madhavan A, Abraham A, Mathew AK, Beevi US, Sukumaran RK, Singh SP, Pandey A (2017). Recent developments in L-glutaminase production and applications - An overview. Bioresource Technology 245:1766-1774.


Bülbül D, KarakuÅŸ E (2013). Production and optimization of L-glutaminase enzyme from Hypocrea jecorina pure culture. Preparative Biochemistry and Biotechnology 43(4):385-97.


Dutt PL, Siddalingeshwara KG, Karthic J, Pramod T, Vishwantha T (2014). Antitumour property L-glutaminase from Aspergillus oryzae through submerged fermentation. International Journal of Current Microbiology and Applied Sciences 3:819-823.


Elemo GN, Elemo BO, Oladunmoye OO, Erukainure OL (2011). Comprehensive investigation into the nutritional composition of dehulled and defatted african locust bean seed (Parkia biglobosa). African Journal of Plant Science 5(5):291-295.


El-Ghonemy DH (2015). Microbial amidases and their industrial applications: A review. Journal of Medical Microbiology and Diagnosis 4:173.


El-Sayed A (2009). L-glutaminase production by Trichoderma koningii under solid state fermentation. Indian Journal of Microbiology (49):243-250.


El-shafei AM, Hassan MM, Abouzeid MA, Mahmoud DA, El-Ghonemy DH (2012). Screening and optimization of l-asparaginase and L-glutaminase production by some filamentous fungi. Advances in Food Sciences 34(3):150-158.


El-Shafei AM, Hassan MM, Abouzeid MA, Mahmoud DA, El-Ghonemy DH (2014). Purification, kinetic properties and antitumor activity of L-glutaminase from Penicillium brevicompactum NRC 829. British Microbiology Research Journal 4:97-115.


Gams W, Bissett J (2002). Morphology and identification of Trichoderma. In: C. P. Kubicek & G. Harman (Eds), Trichoderma and Gliocladium: Basic biology, taxonomy and genetics (vol. 1, pp. 9-30) USA: Taylor and Francis Inc


Hartree EF (1972). Determination of protein: A modification of the lowry method that gives a linear photometric response. Analytical Biochemistry 48(2):422-427.


Imada A, Igarasi S, Nakahama K, Isono M (1973). Asparaginase and glutaminase activities of microorganisms. Microbiology 76:85-99.


Iyer P, Rekha SS, (2010). Production of glutaminase (E.C. from Zygosaccharomyces rouxii in solid-state fermentation and modeling the growth of Z. rouxii therein. Journal of Microbiology and Biotechnology 20(4):737-748.


Jesuraj SA, Praya J, Kingsley R, Kumar LD, Ravikumar M (2013). Bioprocessing of Ar isolates for economical production of l -glutaminase by solid state fermentation. International Journal of ChemTech Research 5(4):1428-1436.


Kashyap P, Sabu A, Pandey A, Szakacs G, Soccol CR (2002). Extra-cellular L-glutaminase production by Zygosaccharomycesrouxii under solid-state fermentation. Process Biochemistry 38(3):307-312.


Kayode JS (2012). African locust bean seed processing: Prospect, status and challenges. Naphtali Prints Nigeria. Ltd Lagos, Nigeria P 13.


Mirkhani F, Alaei H (2015). Species diversity of indigenous Trichoderma from alkaline pistachio soils in Iran. Mycologia Iranica 2:22-37.


Ouoba LI, Rechinger KB, Barkholt V, Diawara B, Traore AS, Jakobsen M (2003). Degradation of proteins during the fermentation of African locust bean (Parkia biglobosa) by strains of Bacillus subtilis and Bacillus pumilus for production of Soumbala. Journal of Applied Microbiology 94(3):396-402.


Sadiku OA (2010). Processing methods influence the quality of fermented african locust bean (Iru/ogiri/dadawa) Parkia biglobosa. Journal of Applied Sciences Research 6(11):1656-1661.


Salihu A, Alam MZ, AbdulKarim MI, Salleh HM (2011). Optimization of lipase production by Candida cylindracea in palm oil mill effluent based medium using statistical experimental design. Journal of Molecular Catalysis B: Enzymatic 69:66-73.


Sarada KV (2013). Production and applications of L-glutaminase using fermentation technology. Asia-Pacific Journal of Operational Research 1:1-4.