African Journal of
Medical and Health Sciences

OFFICIAL PUBLICATION OF THE FEDERAL TEACHING HOSPITAL, ABAKALIKI, NIGERIA
  • Abbreviation: Afr. J. Med. Health Sci.
  • Language: English
  • ISSN: 2384-5589
  • DOI: 10.5897/AJMHS
  • Start Year: 2017
  • Published Articles: 83

Full Length Research Paper

Rectal versus intramuscular diclofenac for pain relief following elective caesarean section at Alex Ekwueme Federal University Teaching Hospital Abakaliki: A randomized controlled trial

Ifeoma C. Uche-Omovoh
  • Ifeoma C. Uche-Omovoh
  • Department of Obstetrics and Gynaecology, Alex Ekwueme Federal University Teaching Hospital, Abakaliki; Ebonyi State, Nigeria
  • Google Scholar
Arinze Ikeotuonye
  • Arinze Ikeotuonye
  • Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra State
  • Google Scholar
Assumpta N. Nweke
  • Assumpta N. Nweke
  • Department of Obstetrics and Gynaecology, Alex Ekwueme Federal University Teaching Hospital, Abakaliki; Ebonyi State, Nigeria
  • Google Scholar
Uzoma E. Ogbo
  • Uzoma E. Ogbo
  • Department of Obstetrics and Gynaecology, Alex Ekwueme Federal University Teaching Hospital, Abakaliki; Ebonyi State, Nigeria
  • Google Scholar
Chinomnso S. Marcel-Onwudiwe
  • Chinomnso S. Marcel-Onwudiwe
  • Department of Obstetrics and Gynaecology, Alex Ekwueme Federal University Teaching Hospital, Abakaliki; Ebonyi State, Nigeria
  • Google Scholar
Chukwudi Olughu Oru
  • Chukwudi Olughu Oru
  • Department of Obstetrics and Gynaecology, Alex Ekwueme Federal University Teaching Hospital, Abakaliki; Ebonyi State, Nigeria
  • Google Scholar
Emmanuel C. Uwakwe
  • Emmanuel C. Uwakwe
  • Department of Obstetrics and Gynaecology, Alex Ekwueme Federal University Teaching Hospital, Abakaliki; Ebonyi State, Nigeria
  • Google Scholar
Cletus Onwe
  • Cletus Onwe
  • Department of Anaesthesia and critical car, Alex Ekwueme Federal University Teaching Hospital Abakaliki, Ebonyi State
  • Google Scholar
Clement Mbanefo
  • Clement Mbanefo
  • Department of Obstetrics and Gynaecology, Alex Ekwueme Federal University Teaching Hospital, Abakaliki; Ebonyi State, Nigeria
  • Google Scholar
Justus N. Eze
  • Justus N. Eze
  • Department of Obstetrics and Gynaecology, Alex Ekwueme Federal University Teaching Hospital, Abakaliki; Ebonyi State, Nigeria
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  •  Received: 02 March 2025
  •  Accepted: 22 May 2025
  •  Published: 30 June 2025

Abstract

Caesarean section (CS) is one of the most common major obstetric surgeries worldwide. Pain control is an integral part of recovery after caesarean section, and NSAIDs have been used in combination with opioids for postoperative pain management in recent times. This study was conceived to compare the efficacy of rectal diclofenac and intramuscular diclofenac as an adjunct to intramuscular pentazocine in the management of postoperative pain in women who had undergone elective caesarean section. The objective was to compare the efficacy of rectal diclofenac with intramuscular diclofenac as pain relief among women after elective Caesarean section at Alex-Ekwueme Federal University Teaching Hospital, Abakaliki (AEFUTHA). This was a randomized controlled trial conducted among pregnant women booked for elective Caesarean section at AEFUTHA, comparing the efficacy of rectal diclofenac with intramuscular diclofenac as pain relief among women after elective caesarean section at term. One arm received a 100mg diclofenac suppository, and the other arm received 75mg of intramuscular diclofenac. These drugs were repeated every 12 h for 24 h. Data were analyzed using IBM SPSS and the intention-to-treat concept. A P-value of < 0.05 was taken to be statistically significant. There was a statistically significant difference in the mean pain scores between the two groups. The number of times maternal request for additional analgesia was also statistically significant. Rectal diclofenac in addition to intramuscular pentazocine was more effective in pain control compared to intramuscular diclofenac in addition to intramuscular pentazocine.
 
Key words: Rectal diclofenac, intramuscular diclofenac, caesarean section, pain relief.