African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5092

Full Length Research Paper

Isolation and phenotypic characterization of actinomycetes from Rabat neighborhood soil and their potential to produce bioactive compounds

Ayoubi Hasnaa
  • Ayoubi Hasnaa
  • Laboratory of Physiopathology and Molecular Genetics, Faculty of Sciences Ben M'Sik, Hassan II University of Casablanca, Avenue Cdt Driss El Harti, PB 7955 Sidi Othman Casablanca, Morocco.
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Mouslim Assia
  • Mouslim Assia
  • Laboratory of Physiopathology and Molecular Genetics, Faculty of Sciences Ben M'Sik, Hassan II University of Casablanca, Avenue Cdt Driss El Harti, PB 7955 Sidi Othman Casablanca, Morocco.
  • Google Scholar
Moujabbir Sara
  • Moujabbir Sara
  • Laboratory of Physiopathology and Molecular Genetics, Faculty of Sciences Ben M'Sik, Hassan II University of Casablanca, Avenue Cdt Driss El Harti, PB 7955 Sidi Othman Casablanca, Morocco.
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Amine Soukaina
  • Amine Soukaina
  • Laboratory of Physiopathology and Molecular Genetics, Faculty of Sciences Ben M'Sik, Hassan II University of Casablanca, Avenue Cdt Driss El Harti, PB 7955 Sidi Othman Casablanca, Morocco.
  • Google Scholar
Azougar Iman
  • Azougar Iman
  • Laboratory of Physiopathology and Molecular Genetics, Faculty of Sciences Ben M'Sik, Hassan II University of Casablanca, Avenue Cdt Driss El Harti, PB 7955 Sidi Othman Casablanca, Morocco.
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Mouslim Jamal
  • Mouslim Jamal
  • Laboratory of Microbiology, Faculty of Sciences Ben M'Sik, Hassan II University of Casablanca, Avenue Cdt Driss El Harti, PB 7955 Sidi Othman Casablanca, Morocco.
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Menggad Mohammed
  • Menggad Mohammed
  • Laboratory of Physiopathology and Molecular Genetics, Faculty of Sciences Ben M'Sik, Hassan II University of Casablanca, Avenue Cdt Driss El Harti, PB 7955 Sidi Othman Casablanca, Morocco.
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  •  Received: 14 November 2017
  •  Accepted: 08 February 2018
  •  Published: 28 February 2018

Abstract

This study aimed to examine the isolation of actinomycetes strains from unexplored Rabat neighbourhood soil followed by phenotypic diversity highlight to access their potential as novel bioactive compounds producers. Twenty nine actinomycetes strains were isolated from southeast of Rabat region. Morphological and cultural characterization, pigment production and antibacterial assay were carried out. All isolates (100%) were able to produce at least one non-diffusible pigment depending on the culture media. Twenty five (86.20%) isolates produce diffusible pigments, 6 (20.69%) produce melanoid diffusible pigments and 5 (17.24%) exhibited antibacterial activities. These results indicate an important potential of the actinomycetes isolated to produce polymorphic secondary metabolites.

Key words: Isolation, actinomycetes, diversity, pigment, bioactive compounds, antibacterial.